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PAR-23-049: NIDA Core "Center of Excellence" Grant Program (P30 Clinical Trial Optional)

Closed Closed November 17, 2025 Opportunity PAR-23-049

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2022.

National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on November 17, 2025.

From the official notice on Grants.gov, last changed December 28, 2022. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-23-049 were run by National Institute on Drug Abuse (NIDA, 9 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-23-049 in the NIH Guide.

Key dates

PostedDecember 28, 2022
DeadlineNovember 17, 2025
Archived by Grants.govDecember 23, 2025

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

NIDA Core Center of Excellence Grants (P30) are intended to bring together investigators currently funded by NIH or other Federal or non-Federal sources, to enhance the effectiveness of existing research and also to extend the focus of research to drug abuse and addiction. It is expected that a Center will transform knowledge in the sciences it is studying. Incremental work should not be the focus of Center activities; rather, new and creative directions are encouraged. An application should integrate and promote research in existing funded projects, to achieve new and creative directions. It is expected that individual core activities reflect a relationship to the integrating theme of the Center and the Center is expected to provide research opportunities and experiences to new investigators , and share findings, data and their resources, consistent with achieving the goals of the program.

Category: Education, Health.

Funded under PAR-23-049 so far

NIH funded 9 projects under PAR-23-049 in fiscal 2024 to 2026, at 9 institutions. The median yearly award was $349,182.

Recently funded projects
ProjectInstitutionFiscal yearAward
Bioinformatics and Biostatistics Core P30Yale University2026$357,945
Bioanalytical Core P30Virginia Commonwealth University2026$252,714
Administrative Core P30Dartmouth College2026$519,610
SAM Core P30University of Colorado Denver2026$316,619
Neurometabolomics and Neuroproteomics Center on Cell-Cell Signaling P30University of Illinois at Urbana-Champaign2026$1.1 million
Administrative Core P30University of Minnesota2026$393,031
Center for Integrative Addiction Neurobiology (CIAN) P30Temple Univ of the Commonwealth2026$2.0 million
Core A P30University of California, San Diego2026$338,204

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Drug Use and Addiction Research Programs grants before

From fiscal 2021 to 2025, Drug Use and Addiction Research Programs (93.279) awarded $7.3 billion across 5,071 grant awards, an average of $1.4 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Yale UnivConnecticut150$305 million
The Johns Hopkins UniversityMaryland156$262 million
University of California, San DiegoCalifornia120$242 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania100$182 million
New York UniversityNew York62$173 million

Top states: California ($1.1 billion), New York ($773 million), Massachusetts ($613 million), Pennsylvania ($488 million), Maryland ($434 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-23-049 still open?

No. It closed on November 17, 2025.

Who can apply for NIDA Core "Center of Excellence" Grant Program (P30 Clinical Trial Optional)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for NIDA Core "Center of Excellence" Grant Program (P30 Clinical Trial Optional)?

Closed November 17, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under PAR-23-049?

NIH RePORTER lists 9 projects funded under PAR-23-049 in fiscal 2024 to 2026, at 9 institutions. The most were at Yale University, Virginia Commonwealth University, Dartmouth College.

Who has won Drug Use and Addiction Research Programs grants before?

The largest recipients over five fiscal years were Yale Univ, The Johns Hopkins University, University of California, San Diego. The program made 5,071 awards worth $7.3 billion in that time.

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