Well Told Grants

Grants / Department of Health and Human Services / National Institutes of Health

PAR-22-071: Toward Translation of Nanotechnology Cancer Interventions (TTNCI) (R01 Clinical Trial Not Allowed)

Closed Closed November 17, 2024 Opportunity PAR-22-071

This grant is closed. A newer notice from the same program is open now: Toward Translation of Nanotechnology Cancer Interventions (TTNCI; R01 Clinical Trial Not Allowed) (PAR-25-336). Status: Due dates in the notice, expires November 15, 2027. It is in our archive of National Institutes of Health notices from 2021.

National Institutes of Health offered grants of up to $475,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on November 17, 2024.

From the official notice on Grants.gov, last changed November 23, 2021. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-22-071 were run by National Cancer Institute (NCI, 10 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-22-071 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PAR-25-336December 16, 2024Due dates in the notice, expires November 15, 2027Open

Key dates

PostedNovember 23, 2021
DeadlineNovember 17, 2024
Archived by Grants.govDecember 23, 2024

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

This Funding Opportunity Announcement (FOA), entitled "Toward Translation of Nanotechnology Cancer Interventions" (TTNCI), encourages applications for advanced pre-clinical research, supporting translation of nanotechnology-based cancer diagnostics and therapeutics. TTNCI awards are designed to mature experimental nanomedicines relying on nanoparticles and nano-devices which demonstrate strong potential to improve cancer treatment effectiveness due to the combination of nanoparticle/nano-device structural design and/or therapeutic/diagnostic cargo which is delivered. TTNCI awards are expected to enable further development of proposed nanotechnology-based interventions to the stage in which they could continue on a developmental path towards the NCI Experimental Therapeutics (NExT) and other NCI translational programs.

Category: Education, Health.

Funded under PAR-22-071 so far

NIH funded 10 projects under PAR-22-071 in fiscal 2023 to 2026, at 10 institutions. The median yearly award was $625,191.

Recently funded projects
ProjectInstitutionFiscal yearAward
Chip-Scale Intraoperative Optical Navigation with Immunotargeted Upconverting Nanoparticles R01University of California, San Francisco2026$637,402
Development of novel nanotherapeutics to overcome therapy resistance using canine brain tumor as a spontaneous model R01University of California at Davis2026$634,743
Interstitial Chemophototherapy as an Intervention in Locally Advanced Pancreatic Cancer R01State University of New York at Buffalo2026$625,191
Next Gen Targeted nanoparticles for Inhibiting Gli2 in Bone Metastatic Tumors R01Vanderbilt University Medical Center2026$647,445
Targeting tumor microenvironment by nanoimmunodrugs for glioma treatment R01Cedars-Sinai Medical Center2026$539,533
Designer extracellular vesicles for cancer therapy R01University of Pennsylvania2026$637,676
Targeted RNA delivery using ribonucleoprotein R01University of Washington2026$604,082
Engineering In Vivo Chimeric Antigen Receptor Macrophages (CARMs) using mRNA-exosomes for Cancer Immunotherapy R01University of TX MD Anderson Can Ctr2025$1.1 million

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Cancer Detection and Diagnosis Research grants before

From fiscal 2021 to 2025, Cancer Detection and Diagnosis Research (93.394) awarded $2.7 billion across 1,944 grant awards, an average of $1.4 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Regents of the University of California, San FranciscoCalifornia56$114 million
Fred Hutchinson Cancer CenterWashington37$96.7 million
The Leland Stanford Junior UniversityCalifornia62$89.1 million
Sloan-Kettering Institute for Cancer ResearchNew York52$88.7 million
The Johns Hopkins UniversityMaryland63$86.5 million

Top states: California ($490 million), New York ($238 million), Massachusetts ($234 million), Pennsylvania ($213 million), Texas ($186 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, PAR-25-336, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-22-071 still open?

No. It closed on November 17, 2024. A newer notice is open: PAR-25-336, due dates in the notice, expires November 15, 2027.

Who can apply for Toward Translation of Nanotechnology Cancer Interventions (TTNCI) (R01 Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Toward Translation of Nanotechnology Cancer Interventions (TTNCI) (R01 Clinical Trial Not Allowed)?

Closed November 17, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $475,000 each.

Who has been funded under PAR-22-071?

NIH RePORTER lists 10 projects funded under PAR-22-071 in fiscal 2023 to 2026, at 10 institutions. The most were at University of California, San Francisco, University of California at Davis, State University of New York at Buffalo.

Who has won Cancer Detection and Diagnosis Research grants before?

The largest recipients over five fiscal years were The Regents of the University of California, San Francisco, Fred Hutchinson Cancer Center, The Leland Stanford Junior University. The program made 1,944 awards worth $2.7 billion in that time.

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