Well Told Grants

Grants / Department of Health and Human Services / National Institutes of Health

PAR-22-069: High Impact, Interdisciplinary Science in NIDDK Research Areas (RC2 Clinical Trial Optional)

Closed Closed October 30, 2024 Opportunity PAR-22-069

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2021.

National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on October 30, 2024.

From the official notice on Grants.gov, last changed November 30, 2021. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-22-069 were run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK, 13 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-22-069 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PAR-25-277December 11, 2024Closed January 22, 2026Closed

Key dates

PostedNovember 30, 2021
DeadlineOctober 30, 2024
Archived by Grants.govDecember 5, 2024

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

The purpose of the High Impact, Interdisciplinary Science grants program is to support high impact ideas that may lay the foundation for new fields of investigation within the mission of NIDDK. The interdisciplinary approach encouraged by this FOA is envisioned to generate a research resource and/or foster discovery-based or hypothesis-generating science that can have a significant impact on the broader scientific community. This FOA seeks novel approaches in areas that address specific knowledge gaps, scientific opportunities, new technologies, data generation, or research methods that will advance the area in significant ways designed to accelerate scientific progress in the understanding, treatment, and prevention of diseases within the mission of the NIDDK.

Category: Food and Nutrition, Health.

Funded under PAR-22-069 so far

NIH funded 13 projects under PAR-22-069 in fiscal 2023 to 2026, at 11 institutions. The median yearly award was $1.7 million.

Most projects: Beth Israel Deaconess Medical Center (Massachusetts), 2, University of Washington (Washington), 2, University of California, San Francisco (California), 1, University of California Los Angeles (California), 1, Joslin Diabetes Center (Massachusetts), 1.

Recently funded projects
ProjectInstitutionFiscal yearAward
A database of indirect calorimetry experiments for the study of energy homeostasis RC2Beth Israel Deaconess Medical Center2026$830,288
Establishing patient-derived iPSCs as a platform for discovery research in NAFLD RC2University of California, San Francisco2026$1.6 million
Investigating Human Adipocyte Heterogeneity RC2Beth Israel Deaconess Medical Center2026$2.1 million
AI-designed mini-proteins as drivers of pancreatic islet production from pluripotent stem cells RC2University of Washington2026$1.7 million
COngenital Diarrhea and Enteropathy (PediCODE) Consortium and BioRepository RC2University of California Los Angeles2026$1.7 million
Epitranscriptomics in human obesity and type 2 diabetes RC2Joslin Diabetes Center2026$2.0 million
Resources to interpret genetic signals and multi-tissue mechanisms for type 2 diabetes and related traits RC2Univ of North Carolina Chapel Hill2026$1.6 million
Spatial and temporal resolution to dissect cellular circuits controlling intestinal physiology, immunity, and inflammatory pathologies RC2Broad Institute, Inc.2026$2.0 million

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Diabetes, Digestive, and Kidney Diseases Extramural Research grants before

From fiscal 2021 to 2025, Diabetes, Digestive, and Kidney Diseases Extramural Research (93.847) awarded $9.6 billion across 7,877 grant awards, an average of $1.2 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Regents of the University of MichiganMichigan273$345 million
The Trustees of the University of PennsylvaniaPennsylvania187$272 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania209$238 million
The Washington UniversityMissouri187$227 million
The Regents of the University of California, San FranciscoCalifornia176$208 million

Top states: California ($1.2 billion), Massachusetts ($932 million), New York ($798 million), Pennsylvania ($762 million), Texas ($482 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-22-069 still open?

No. It closed on October 30, 2024.

Who can apply for High Impact, Interdisciplinary Science in NIDDK Research Areas (RC2 Clinical Trial Optional)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for High Impact, Interdisciplinary Science in NIDDK Research Areas (RC2 Clinical Trial Optional)?

Closed October 30, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under PAR-22-069?

NIH RePORTER lists 13 projects funded under PAR-22-069 in fiscal 2023 to 2026, at 11 institutions. The most were at Beth Israel Deaconess Medical Center, University of Washington, University of California, San Francisco.

Who has won Diabetes, Digestive, and Kidney Diseases Extramural Research grants before?

The largest recipients over five fiscal years were Regents of the University of Michigan, The Trustees of the University of Pennsylvania, University of Pittsburgh - of the Commonwealth System of Higher Education. The program made 7,877 awards worth $9.6 billion in that time.

Similar open grants