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Grants / Department of Health and Human Services / National Institutes of Health

PAR-22-039: Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R01 Clinical Trial Not Allowed)

Closed Closed January 7, 2025 Opportunity PAR-22-039

This grant is closed. A newer notice from the same program is open now: Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R01 Clinical Trial Not Allowed) (PAR-25-287). Status: Due dates in the notice, expires January 7, 2028. It is in our archive of National Institutes of Health notices from 2021.

National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on January 7, 2025.

From the official notice on Grants.gov, last changed October 12, 2021. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-22-039 were run by National Institute of Mental Health (NIMH, 1 project). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

This notice replaced PAR-18-942.

Application due dates, page limits and budget limits are set in the notice. Read PAR-22-039 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PAR-25-287November 21, 2024Due dates in the notice, expires January 7, 2028Open

Key dates

PostedOctober 12, 2021
DeadlineJanuary 7, 2025
Archived by Grants.govFebruary 12, 2025

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

Reissue of PAR-18-942. The purpose of this funding opportunity announcement (FOA) is to encourage applications seeking to develop the next generation of brain stimulation devices for treating mental health disorders. Applications are sought that will either 1) develop novel brain stimulation devices or 2) significantly enhance, by means of hardware/software improvements, the effectiveness of brain stimulation devices that are currently U.S. Food and Drug Administration (FDA)-approved or cleared. Novel devices should move beyond existing electrical/magnetic stimulation and develop new stimulation techniques capable of increased spatiotemporal precision as well as multi-focal, closed-loop approaches. Applications seeking to develop new capabilities should focus on significant enhancement of the spatial resolution, depth of delivery, and/or precision of the device. Incremental changes to existing devices (e.g., software updates) are not withinthe scope of this announcement.

Category: Health.

Funded under PAR-22-039 so far

NIH funded 1 project under PAR-22-039 in fiscal 2023 to 2026, at 1 institution. The median yearly award was $777,418.

Recently funded projects
ProjectInstitutionFiscal yearAward
Next generation transcranial ultrasound-based neuromodulation using phase shift nanoemulsions R01Vanderbilt University Medical Center2026$765,144

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Mental Health Research Grants grants before

From fiscal 2021 to 2025, Mental Health Research Grants (93.242) awarded $8.8 billion across 6,785 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Yale UnivConnecticut185$371 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania200$297 million
University of California, Los AngelesCalifornia176$234 million
Icahn School of Medicine at Mount SinaiNew York144$212 million
The Washington UniversityMissouri149$211 million

Top states: California ($1.4 billion), Massachusetts ($1.1 billion), New York ($1.1 billion), Pennsylvania ($667 million), Connecticut ($422 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, PAR-25-287, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-22-039 still open?

No. It closed on January 7, 2025. A newer notice is open: PAR-25-287, due dates in the notice, expires January 7, 2028.

Who can apply for Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R01 Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R01 Clinical Trial Not Allowed)?

Closed January 7, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under PAR-22-039?

NIH RePORTER lists 1 project funded under PAR-22-039 in fiscal 2023 to 2026, at 1 institution.

Who has won Mental Health Research Grants grants before?

The largest recipients over five fiscal years were Yale Univ, University of Pittsburgh - of the Commonwealth System of Higher Education, University of California, Los Angeles. The program made 6,785 awards worth $8.8 billion in that time.

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