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Grants / Department of Health and Human Services / National Institutes of Health

PAR-21-166: Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Not Allowed)

Closed Closed December 30, 2024 Opportunity PAR-21-166

This grant is closed. A newer notice from the same program is open now: Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Not Allowed) (PAR-25-338). Status: Due dates in the notice, expires January 7, 2028. It is in our archive of National Institutes of Health notices from 2021.

National Institutes of Health offered grants of up to $499,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on December 30, 2024.

From the official notice on Grants.gov, last changed December 31, 2024. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-21-166 were run by National Cancer Institute (NCI, 23 projects) and National Institute of Biomedical Imaging and Bioengineering (NIBIB, 1 project). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-21-166 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PAR-25-338December 31, 2024Due dates in the notice, expires January 7, 2028Open

Key dates

PostedMarch 25, 2021
DeadlineDecember 30, 2024
Archived by Grants.govJanuary 29, 2025

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

The purpose of this Funding Opportunity Announcement (FOA) is to stimulate efforts to translate scientific discoveries and engineering developments into methods or tools that address problems in basic research to understand disease, or in applied research to assess risk, detect, prevent, diagnose, treat, and/or manage disease. The rationale is to deliver new capabilities to meet evolving requirements for technologies and methods relevant to the advance of research and delivery of care in pre-clinical, clinical and non-clinical settings, domestic or foreign, for conditions and diseases within the missions of participating institutes.

Category: Education, Health.

Funded under PAR-21-166 so far

NIH funded 24 projects under PAR-21-166 in fiscal 2022 to 2026, at 20 institutions. The median yearly award was $606,391.

Most projects: University of Southern California (California), 2, Massachusetts General Hospital (Massachusetts), 2, University of Texas HLTH Science Center (Texas), 2, Johns Hopkins University (Maryland), 2, Baylor College of Medicine (Texas), 1.

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Cancer Treatment Research grants before

From fiscal 2021 to 2025, Cancer Treatment Research (93.395) awarded $5.6 billion across 3,622 grant awards, an average of $1.5 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Univeristy of Texas M.D. Anderson Cancer CenterTexas144$188 million
Dana-Farber Cancer Institute, Inc.Massachusetts68$185 million
Icahn School of Medicine at Mount SinaiNew York35$179 million
Public Health InstituteCalifornia4$168 million
Fred Hutchinson Cancer CenterWashington57$156 million

Top states: California ($843 million), New York ($604 million), Massachusetts ($568 million), Texas ($444 million), Pennsylvania ($417 million).

Who has won Cancer Detection and Diagnosis Research grants before

From fiscal 2021 to 2025, Cancer Detection and Diagnosis Research (93.394) awarded $2.7 billion across 1,944 grant awards, an average of $1.4 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Regents of the University of California, San FranciscoCalifornia56$114 million
Fred Hutchinson Cancer CenterWashington37$96.7 million
The Leland Stanford Junior UniversityCalifornia62$89.1 million
Sloan-Kettering Institute for Cancer ResearchNew York52$88.7 million
The Johns Hopkins UniversityMaryland63$86.5 million

Top states: California ($490 million), New York ($238 million), Massachusetts ($234 million), Pennsylvania ($213 million), Texas ($186 million).

Who has won Oral Diseases and Disorders Research grants before

From fiscal 2021 to 2025, Oral Diseases and Disorders Research (93.121) awarded $1.9 billion across 2,263 grant awards, an average of $818,037 per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Regents of the University of MichiganMichigan76$89.2 million
The Regents of the University of California, San FranciscoCalifornia84$80.5 million
University of Southern CaliforniaCalifornia41$78.6 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania58$55.9 million
The Trustees of the University of PennsylvaniaPennsylvania66$51.5 million

Top states: California ($330 million), Massachusetts ($159 million), Pennsylvania ($147 million), Texas ($137 million), New York ($136 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, PAR-25-338, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-21-166 still open?

No. It closed on December 30, 2024. A newer notice is open: PAR-25-338, due dates in the notice, expires January 7, 2028.

Who can apply for Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Not Allowed)?

Closed December 30, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $499,000 each.

Who has been funded under PAR-21-166?

NIH RePORTER lists 24 projects funded under PAR-21-166 in fiscal 2022 to 2026, at 20 institutions. The most were at University of Southern California, Massachusetts General Hospital, University of Texas HLTH Science Center.

Who has won Oral Diseases and Disorders Research grants before?

The largest recipients over five fiscal years were Regents of the University of Michigan, The Regents of the University of California, San Francisco, University of Southern California. The program made 2,263 awards worth $1.9 billion in that time.

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