Well Told Grants

Grants / Department of Health and Human Services / National Institutes of Health

PA-25-246: Small Research Grant Program for the Next Generation of Researchers in AD/ADRD Research (R03 Clinical Trial Optional)

Closed Closed March 16, 2026 Opportunity PA-25-246

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2024.

National Institutes of Health offered grants of up to $100,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It expected to make $100,000 in total. Applications closed on March 16, 2026.

From the official notice on Grants.gov, last changed November 18, 2024. Checked November 7, 2026.

About this NIH notice

Projects funded under PA-25-246 were run by National Institute on Aging (NIA, 28 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PA-25-246 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PAR-23-179April 24, 2023Closed November 17, 2024Closed

Key dates

PostedNovember 18, 2024
DeadlineMarch 16, 2026
Archived by Grants.govApril 21, 2026

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

This Small Research Grant (R03) will support meritorious projects to provide needed scientific insight to improve the prevention, diagnosis, treatment, and/or care for individuals with Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD). Specifically, this NOFO will support projects covering a wide range of topics related to AD/ADRD. The overall goal of this NOFO is (i) to encourage the next generation of researchers to pursue research and academic careers in AD/ADRD research; and (ii) to stimulate established researchers who have not had a major award in AD/ADRD research to perform pilot studies to develop new, innovative AD/ADRD research programs that leverage and build upon their existing expertise.

Category: Health.

Funded under PA-25-246 so far

NIH funded 28 projects under PA-25-246 in fiscal 2026, at 25 institutions. The median yearly award was $312,000.

Most projects: University of Texas HLTH Sci Ctr Houston (Texas), 2, Massachusetts General Hospital (Massachusetts), 2, Utah State Higher Education System--University of Utah (Utah), 2, Boston University Medical Campus (Massachusetts), 1, Virginia Polytechnic Inst and St Univ (Virginia), 1.

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Aging Research grants before

From fiscal 2021 to 2025, Aging Research (93.866) awarded $19 billion across 11,026 grant awards, an average of $1.7 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Regents of the University of California, San FranciscoCalifornia337$575 million
The Trustees of Columbia University in the City of New YorkNew York242$574 million
University of Southern CaliforniaCalifornia203$572 million
The Washington UniversityMissouri210$556 million
Regents of the University of MichiganMichigan232$538 million

Top states: California ($3.4 billion), New York ($2.0 billion), Massachusetts ($1.8 billion), Pennsylvania ($1.0 billion), Texas ($912 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PA-25-246 still open?

No. It closed on March 16, 2026.

Who can apply for Small Research Grant Program for the Next Generation of Researchers in AD/ADRD Research (R03 Clinical Trial Optional)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Small Research Grant Program for the Next Generation of Researchers in AD/ADRD Research (R03 Clinical Trial Optional)?

Closed March 16, 2026. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $100,000 each. About $100,000 in total.

Who has been funded under PA-25-246?

NIH RePORTER lists 28 projects funded under PA-25-246 in fiscal 2026, at 25 institutions. The most were at University of Texas HLTH Sci Ctr Houston, Massachusetts General Hospital, Utah State Higher Education System--University of Utah.

Who has won Aging Research grants before?

The largest recipients over five fiscal years were The Regents of the University of California, San Francisco, The Trustees of Columbia University in the City of New York, University of Southern California. The program made 11,026 awards worth $19 billion in that time.

Similar open grants