PA-25-163: Alcohol Treatment, Pharmacotherapy, and Recovery Research (R01 Clinical Trial Required)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2024.
National Institutes of Health offered grants of up to $500,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It expected to make $500,000 in total. Applications closed on September 7, 2026.
From the official notice on Grants.gov, last changed November 27, 2024. Checked November 7, 2026.
- Award ceiling$500,000
- Total funding$500,000
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeR01
- Clinical trialsRequired
- Funded byNIAAA
- Median yearly award$688,500
- Typical project length5 years
- R01, Research Project Grant. NIH's standard grant for a defined research project led by a named investigator, usually for up to five years. Other open R01 notices.
Projects funded under PA-25-163 were run by National Institute on Alcohol Abuse and Alcoholism (NIAAA, 3 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read PA-25-163 in the NIH Guide.
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| PAR-23-250 | August 9, 2023 | Closed November 26, 2024 | Closed |
Key dates
| Posted | November 27, 2024 |
|---|---|
| Deadline | September 7, 2026 |
| Archived by Grants.gov | October 13, 2026 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Is this a realistic fit?
- Projects NIH funded under this notice had a median yearly award of $688,500; it allows up to $500,000 per award.
- Most of the program's money (73% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The National Institute on Alcohol Abuse and Alcoholism solicits applications for an R01 Clinical Trial Required mechanism focusing on alcohol treatment and recovery research. This NOFO will focus broadly on topics relevant for treatment of and recovery from alcohol use disorder (AUD), including: medications development, precision medicine, behavioral therapies and mechanisms of behavioral change (MOBC), recovery, translational research, and innovative methods and technologies for AUD treatment and recovery.
Funded under PA-25-163 so far
NIH funded 3 projects under PA-25-163 in fiscal 2026, at 3 institutions. The median yearly award was $688,500.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| Daridorexant for the treatment of sleep amongst those with an alcohol use disorder using the addictions neuroclinical assessment framework | Washington State University | 2026 | $688,500 |
| N-acetylcysteine for restoring glutamate/glutathione homeostasis and reducing heavy drinking in co-occurring bipolar and alcohol use disorders | Medical University of South Carolina | 2026 | $674,482 |
| The effects of psilocybin and brain stimulation on the treatment of alcohol use disorder | Johns Hopkins University | 2026 | $689,697 |
Who has won Alcohol Research Programs grants before
From fiscal 2021 to 2025, Alcohol Research Programs (93.273) awarded $2.2 billion across 2,255 grant awards, an average of $974,579 per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Yale Univ | Connecticut | 75 | $86.5 million |
| University of North Carolina at Chapel Hill | North Carolina | 76 | $60.7 million |
| Trustees of Indiana University | Indiana | 47 | $54.8 million |
| University of California, San Diego | California | 47 | $54.5 million |
| The Medical University of South Carolina | South Carolina | 57 | $45.8 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is PA-25-163 still open?
No. It closed on September 7, 2026.
Who can apply for Alcohol Treatment, Pharmacotherapy, and Recovery Research (R01 Clinical Trial Required)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Alcohol Treatment, Pharmacotherapy, and Recovery Research (R01 Clinical Trial Required)?
Closed September 7, 2026. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $500,000 each. About $500,000 in total.
Who has been funded under PA-25-163?
NIH RePORTER lists 3 projects funded under PA-25-163 in fiscal 2026, at 3 institutions. The most were at Washington State University, Medical University of South Carolina, Johns Hopkins University.
Who has won Alcohol Research Programs grants before?
The largest recipients over five fiscal years were Yale Univ, University of North Carolina at Chapel Hill, Trustees of Indiana University. The program made 2,255 awards worth $2.2 billion in that time.
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