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Grants / Department of Health and Human Services / National Institutes of Health

PA-25-126: NICHD Small Research Grant Program (R03 Basic Experimental Studies with Humans Required)

Closed Closed May 24, 2026 Opportunity PA-25-126

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2024.

National Institutes of Health offered grants of up to $50,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It expected to make $50,000 in total. Applications closed on May 24, 2026.

From the official notice on Grants.gov, last changed April 21, 2026. Checked November 7, 2026.

About this NIH notice

Application due dates, page limits and budget limits are set in the notice. Read PA-25-126 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PA-21-231April 21, 2021Closed January 7, 2025Closed

Key dates

PostedNovember 18, 2024
DeadlineMay 24, 2026
Archived by Grants.govJune 23, 2026

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

The NICHD Small Research Grant Program (R03Basic Experimental Studies with HumansRequired) supports clinical trials that fall within the NICHD mission and also meet the criteria for basic science experimental studies involving humans (BESH), referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should submit under this NOFO include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind.

Category: Health, Income Security and Social Services.

Who has won Child Health and Human Development Extramural Research grants before

From fiscal 2021 to 2025, Child Health and Human Development Extramural Research (93.865) awarded $6.0 billion across 6,026 grant awards, an average of $1.0 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Regents of the University of MichiganMichigan167$178 million
The Johns Hopkins UniversityMaryland133$146 million
University of WashingtonWashington114$131 million
Baylor College of MedicineTexas116$124 million
The Leland Stanford Junior UniversityCalifornia104$116 million

Top states: California ($726 million), Massachusetts ($579 million), New York ($456 million), Pennsylvania ($419 million), North Carolina ($365 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PA-25-126 still open?

No. It closed on May 24, 2026.

Who can apply for NICHD Small Research Grant Program (R03 Basic Experimental Studies with Humans Required)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for NICHD Small Research Grant Program (R03 Basic Experimental Studies with Humans Required)?

Closed May 24, 2026. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $50,000 each. About $50,000 in total.

Who has won Child Health and Human Development Extramural Research grants before?

The largest recipients over five fiscal years were Regents of the University of Michigan, The Johns Hopkins University, University of Washington. The program made 6,026 awards worth $6.0 billion in that time.

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