PA-21-221: NICHD Small Research Grant Program (R03 Clinical Trial Required)
Closed
This grant is closed. A newer notice from the same program is open now: NICHD Small Research Grant Program (R03 Clinical Trial Required) (PA-25-125). Status: Due dates in the notice, expires January 7, 2028. It is in our archive of National Institutes of Health notices from 2021.
National Institutes of Health offered grants of up to $50,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on January 7, 2025.
From the official notice on Grants.gov, last changed April 11, 2024. Checked November 7, 2026.
- Award ceiling$50,000
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeR03
- Clinical trialsRequired
- Funded byNICHD
- Median yearly award$148,449
- Typical project length2 years
- R03, Small Grant. A small, short project such as pilot work, a feasibility study, secondary data analysis or a new method, usually for up to two years. Other open R03 notices.
Projects funded under PA-21-221 were run by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD, 8 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read PA-21-221 in the NIH Guide.
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| PA-25-125 | November 18, 2024 | Due dates in the notice, expires January 7, 2028 | Open |
Key dates
| Posted | April 21, 2021 |
|---|---|
| Deadline | January 7, 2025 |
| Archived by Grants.gov | February 6, 2025 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Is this a realistic fit?
- Projects NIH funded under this notice had a median yearly award of $148,449; it allows up to $50,000 per award.
- Most of the program's money (72% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The NICHD Small Research Grant Program (Clinical Trial Required) supports clinical trials that fall within the NICHD mission.
Funded under PA-21-221 so far
NIH funded 8 projects under PA-21-221 in fiscal 2022 to 2025, at 8 institutions. The median yearly award was $148,449.
Who has won Child Health and Human Development Extramural Research grants before
From fiscal 2021 to 2025, Child Health and Human Development Extramural Research (93.865) awarded $6.0 billion across 6,026 grant awards, an average of $1.0 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Regents of the University of Michigan | Michigan | 167 | $178 million |
| The Johns Hopkins University | Maryland | 133 | $146 million |
| University of Washington | Washington | 114 | $131 million |
| Baylor College of Medicine | Texas | 116 | $124 million |
| The Leland Stanford Junior University | California | 104 | $116 million |
Applying now
This notice no longer takes applications. Apply under the newer notice, PA-25-125, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is PA-21-221 still open?
No. It closed on January 7, 2025. A newer notice is open: PA-25-125, due dates in the notice, expires January 7, 2028.
Who can apply for NICHD Small Research Grant Program (R03 Clinical Trial Required)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for NICHD Small Research Grant Program (R03 Clinical Trial Required)?
Closed January 7, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $50,000 each.
Who has been funded under PA-21-221?
NIH RePORTER lists 8 projects funded under PA-21-221 in fiscal 2022 to 2025, at 8 institutions. The most were at Miami University Oxford, University of Pittsburgh at Pittsburgh, University of Central Florida.
Who has won Child Health and Human Development Extramural Research grants before?
The largest recipients over five fiscal years were Regents of the University of Michigan, The Johns Hopkins University, University of Washington. The program made 6,026 awards worth $6.0 billion in that time.
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