NOT-NS-24-061: Notice of Intent to Publish a Funding Opportunity Announcement for Morris K. Udall Discovery Centers without Walls (DCWoW) for Parkinson's Disease Research (RM1 - Clinical Trial Optional)
Forecast
This forecast is out of date. Its expected dates have passed and the agency has not posted the opportunity on Grants.gov. It may be delayed or cancelled; check the program's other opportunities below.
National Institutes of Health plans to offer grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It is a forecast: the notice is expected around October 6, 2025, with applications due around February 6, 2026.
From the official notice on Grants.gov, last changed May 27, 2025. Checked November 7, 2026.
- Award amountsNot given on Grants.gov
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeRM1
- Clinical trialsOptional
- RM1, Research Project with Complex Structure. A large research project with several connected parts under one award. Other open RM1 notices.
Key dates
| Forecast posted | August 26, 2024 |
|---|---|
| Expected posting | October 6, 2025 |
| Expected deadline | February 6, 2026 |
| Expected award date | October 6, 2026 |
Add the deadline to your calendar or it to My grants.
Who can apply
This opportunity is open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 11 applicant types the notice lists
- State governments
- County governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
Is this a realistic fit?
- Most of the program's money (76% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The National Institute of Neurological Disorders and Stroke (NINDS) intends to promote team science research to discover the causes of Parkinson's Disease by publishing a Notice of Funding Opportunity (NOFO) to solicit applications for Morris K. Udall Discovery Centers without Walls (DCWoW) for Parkinson's Disease Research. Parkinson’s disease (PD) is a chronic, progressive movement disorder that affects the lives of at least half a million people across the United States (US), as well as having significant impact on the relatives and friends who care for them. The average onset of characteristic motor symptoms, which are initially subtle and increasingly impact purposeful movement, most often occurs in the sixth decade of life; onset at much younger ages is also possible. Persons with PD also experience a broad range of non-motor symptoms including autonomic dysfunction (e.g. constipation, urinary incontinence, orthostatic hypotension, sexual dysfunction), sleep disturbances, pain, changes in mood, and cognitive dysfunction potentially leading to dementia. Available pharmacological and surgical treatments provide limited relief from some motor symptoms but fail to address non-motor symptoms or attenuate the ultimate progression of the disease. A clear cause and definitive cure have remained elusive despite important biomedical research advances, such as the identification of environmental and genetic risk factors. As our population ages, the number of persons with PD is projected to increase significantly; mounting evidence suggests that global burden, including disability and mortality due to PD, are increasing at a more rapid rate compared with other neurological diseases. In recognition of the impact of PD on our society, and to advance innovative research into the causes of PD, this initiative will promote biomedical discovery through an integrated team science approach. Established in 1998 via the Morris K. Udall Parkinson's Disease Research Act (P.L. 105-78), the NINDS Udall Centers of Excellence for PD Research program is a central component of NINDS-supported PD research. This new initiative will extend the Udall Centers program in novel directions and enable applicants to focus on discovery research not possible via other grant mechanisms. This Notice encourages investigators with expertise, insights, and innovative approaches in the area of Parkinson's disease and related synucleinopathies to begin to consider applying for this new NOFO.
Who has won Extramural Research Programs in the Neurosciences and Neurological Disorders grants before
From fiscal 2021 to 2025, Extramural Research Programs in the Neurosciences and Neurological Disorders (93.853) awarded $9.1 billion across 8,641 grant awards, an average of $1.0 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The General Hospital Corporation | Massachusetts | 203 | $288 million |
| The Regents of the University of California, San Francisco | California | 248 | $277 million |
| The Johns Hopkins University | Maryland | 230 | $276 million |
| The Trustees of Columbia University in the City of New York | New York | 188 | $226 million |
| Regents of the University of Michigan | Michigan | 179 | $221 million |
How to apply
- Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
- Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
- Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.
Questions go to Beth Anne Sieber, PhD, National Institute of Neurological Disorders and Stroke (NINDS), Beth-Anne.Sieber@nih.gov, 301-827-3587.
Questions people ask
Is NOT-NS-24-061 still open?
Not yet. It is a forecast: expected deadline February 6, 2026.
Who can apply for Notice of Intent to Publish a Funding Opportunity Announcement for Morris K. Udall Discovery Centers without Walls (DCWoW) for Parkinson's Disease Research (RM1 - Clinical Trial Optional)?
National Institutes of Health accepts applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
What is the deadline for Notice of Intent to Publish a Funding Opportunity Announcement for Morris K. Udall Discovery Centers without Walls (DCWoW) for Parkinson's Disease Research (RM1 - Clinical Trial Optional)?
Expected deadline February 6, 2026. Confirm the date and time in the official notice on Grants.gov.
Who has won Extramural Research Programs in the Neurosciences and Neurological Disorders grants before?
The largest recipients over five fiscal years were The General Hospital Corporation, The Regents of the University of California, San Francisco, The Johns Hopkins University. The program made 8,641 awards worth $9.1 billion in that time.
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