NOT-CA-25-105: Forecast to Publish a Notice of Funding Opportunity for Paul Calabresi Career Development Award in Clinical Oncology (K12 Clinical Trial Optional)
Forecast
This forecast is out of date. Its expected dates have passed and the agency has not posted the opportunity on Grants.gov. It may be delayed or cancelled; check the program's other opportunities below.
National Institutes of Health plans to offer grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It expects to make about 15 awards. It is a forecast: the notice is expected around December 1, 2025, with applications due around February 18, 2026.
From the official notice on Grants.gov, last changed July 1, 2025. Checked November 7, 2026.
- Expected awards15
- Award amountsNot given on Grants.gov
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeK12
- Clinical trialsOptional
- K12, Institutional Career Development Program. An institution's program that places early-career researchers in mentored career development. Other open K12 notices.
Key dates
| Forecast posted | July 1, 2025 |
|---|---|
| Expected posting | December 1, 2025 |
| Expected deadline | February 18, 2026 |
| Expected award date | January 6, 2027 |
Add the deadline to your calendar or it to My grants.
Who can apply
This opportunity is open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 11 applicant types the notice lists
- State governments
- County governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
Is this a realistic fit?
- Most of the program's money (72% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The National Cancer Institute (NCI) intends to publish a Notice of Funding Opportunity (NOFO), the Paul Calabresi Career Development Award for Clinical Oncology (K12). The NOFO will invite applications for institutional research career development programs to support the training of clinical scientists in cancer research. The purpose of the Paul Calabresi Career Development Award for Clinical Oncology, is to increase the number of clinician-scientists trained in clinical and translational cancer research, promote their career development, and prepare them to be effective scientific partners with basic research scientists. NCI Calabresi K12 programs are required to have at least two oncology specialties represented among the included faculty and the pool of K12 appointees (Scholars). The programs are expected to leverage the institution’s unique strengths in these oncology specialties and to incorporate the latest research and technology advancements in designing cutting-edge career development curricula. And the programs must establish individualized career development plans to accommodate Scholars with different levels of prior research training/experience and assign two mentors, a clinician conducting patient-oriented research and a basic science cancer researcher, to each Scholar. The award budgets may include salary support for the PD(s)/PI(s) and Scholars, research and development support, and administrative support costs. The application must clearly indicate the number of Scholar appointments proposed for each year. Candidates must have a full-time appointment at the applicant institution or a partnering institution. Scholar support is provided for a minimum of two years and a maximum of three years of consecutive funding for each scholar, consisting of 12-month appointments, provided their progress towards an independent academic career is on track and satisfactory. The program will allow the appointment of Scholars proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary study to an existing trial; or proposing to gain research experience in a clinical trial led by another investigator as part of their research and career development.
Who has won Cancer Research Manpower grants before
From fiscal 2021 to 2025, Cancer Research Manpower (93.398) awarded $1.0 billion across 2,913 grant awards, an average of $359,612 per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Sloan-Kettering Institute for Cancer Research | New York | 92 | $52.8 million |
| Dana-Farber Cancer Institute, Inc. | Massachusetts | 100 | $38.4 million |
| The Univeristy of Texas M.D. Anderson Cancer Center | Texas | 65 | $35.5 million |
| The General Hospital Corporation | Massachusetts | 58 | $35.4 million |
| The Johns Hopkins University | Maryland | 69 | $33.7 million |
How to apply
- Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
- Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
- Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.
Questions go to Mark Damico, Ph.D., National Cancer Institute (NCI), damicomw@nih.gov, 240-276-5630.
Questions people ask
Is NOT-CA-25-105 still open?
Not yet. It is a forecast: expected deadline February 18, 2026.
Who can apply for Forecast to Publish a Notice of Funding Opportunity for Paul Calabresi Career Development Award in Clinical Oncology (K12 Clinical Trial Optional)?
National Institutes of Health accepts applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
What is the deadline for Forecast to Publish a Notice of Funding Opportunity for Paul Calabresi Career Development Award in Clinical Oncology (K12 Clinical Trial Optional)?
Expected deadline February 18, 2026. Confirm the date and time in the official notice on Grants.gov.
Who has won Cancer Research Manpower grants before?
The largest recipients over five fiscal years were Sloan-Kettering Institute for Cancer Research, Dana-Farber Cancer Institute, Inc., The Univeristy of Texas M.D. Anderson Cancer Center. The program made 2,913 awards worth $1.0 billion in that time.
Similar open grants
- NIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional)
- Limited Competition: Mentored Research Career Development Program Award in Clinical and Translational Science Awards (CTSA) Program (K12 Clinical Trial Optional)
- R3PEATS Rigor Scholar Cohort Awards (K12)
- Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
- Paul Calabresi Career Development Award for Clinical Oncology (K12 Clinical Trial Not Allowed)
- Institutional Mentored Career Development Award (Parent K12) (Clinical Trials Not Allowed)