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Grants / Department of Defense / Defense Health Agency Contracting Activity - DHACA

HT942525AZRPTRRA: Alzheimer’s Research Program Transforming Research Award

Closed Closed August 29, 2025 Opportunity HT942525AZRPTRRA

This grant is closed. A newer notice from the same program is open now: DoW Breast Cancer, Clinical Research Extension Award (HT942526BCRPCREA2). Status: Closes November 18, 2026 (11 days left). It is in our archive of Defense Health Agency Contracting Activity - DHACA notices from 2025.

Defense Health Agency Contracting Activity - DHACA offered grants to any type of organization. It expected to make about 4 awards worth $4.0 million in total. Applications closed on August 29, 2025.

From the official notice on Grants.gov, last changed April 18, 2025. Checked November 7, 2026.

Key dates

PostedApril 18, 2025
DeadlineAugust 29, 2025
Archived by Grants.govSeptember 28, 2025

Who can apply

This opportunity was open to any type of organization.

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Is this a realistic fit?

What the grant funds

Summary: Supports non-incremental research designed to reduce risk of or prevent the development of Alzheimer’s disease and/or Alzheimer's disease related dementias (AD/ADRD). Allowable research includes projects utilizing animal models as well as clinical research projects. Distinctive Features: This funding opportunity allows for multiple principal investigators (PIs) under the Career Initiation or Transition (CIT) Partnership Option. If utilizing this option, only the initiating PI will submit a pre-application, but each PI will need to submit a full application. Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn. Community collaboration is required for projects proposing clinical research. Leveraging existing resources and cohorts, particularly those that address critical health challenges and facilitate applicability to military health, is strongly encouraged.

Category: Science and Technology and other Research and Development.

Who has won Military Medical Research and Development grants before

From fiscal 2021 to 2025, Military Medical Research and Development (12.420) awarded $6.9 billion across 5,470 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.Maryland81$546 million
The Univeristy of Texas M.D. Anderson Cancer CenterTexas139$166 million
The Johns Hopkins UniversityMaryland157$153 million
The Regents of the University of California, San FranciscoCalifornia113$147 million
Duke UniversityNorth Carolina86$123 million

Top states: Maryland ($793 million), California ($751 million), Texas ($598 million), Massachusetts ($586 million), New York ($508 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, HT942526BCRPCREA2, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is HT942525AZRPTRRA still open?

No. It closed on August 29, 2025. A newer notice is open: HT942526BCRPCREA2, closes November 18, 2026 (11 days left).

Who can apply for Alzheimer’s Research Program Transforming Research Award?

Defense Health Agency Contracting Activity - DHACA accepted applications from any type of organization.

What is the deadline for Alzheimer’s Research Program Transforming Research Award?

Closed August 29, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

About $4.0 million in total across about 4 awards.

Who has won Military Medical Research and Development grants before?

The largest recipients over five fiscal years were The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., The Univeristy of Texas M.D. Anderson Cancer Center, The Johns Hopkins University. The program made 5,470 awards worth $6.9 billion in that time.

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