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Grants / Department of Defense / Defense Health Agency Contracting Activity - DHACA

HT942524MSRPEHDA: DoD Multiple Sclerosis, Exploration - Hypothesis Development Award

Closed Closed October 7, 2024 Opportunity HT942524MSRPEHDA

This grant is closed. A newer notice from the same program is open now: DoW Breast Cancer, Clinical Research Extension Award (HT942526BCRPCREA2). Status: Closes November 18, 2026 (11 days left). It is in our archive of Defense Health Agency Contracting Activity - DHACA notices from 2024.

Defense Health Agency Contracting Activity - DHACA offered grants to any type of organization. It expected to make about 8 awards worth $2.0 million in total. Applications closed on October 7, 2024.

From the official notice on Grants.gov, last changed April 19, 2024. Checked November 7, 2026.

Other notices with this title

Defense Health Agency Contracting Activity - DHACA has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
HT9425-23-MSRP-EHDAApril 14, 2023Closed October 6, 2023Closed
W81XWH-22-MSRP-EHDAApril 29, 2022Closed October 7, 2022Closed
W81XWH-21-MSRP-EHDAMay 10, 2021Closed October 1, 2021Closed

Key dates

PostedApril 19, 2024
DeadlineOctober 7, 2024
Archived by Grants.govNovember 6, 2024

Who can apply

This opportunity was open to any type of organization.

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Is this a realistic fit?

What the grant funds

The MSRP EHDA supports the initial exploration of innovative, high-risk, high-gain, and potentially groundbreaking concepts in the MS research field. The studies supported by this award mechanism are expected to lay the groundwork for future avenues of scientific investigation. The proposed research project should include a well-formulated, testable hypothesis based on strong scientific rationale and study design. The presentation of preliminary and/or published data is not required. The proposed research project must be innovative. Innovative research may examine a novel paradigm, challenge current paradigms, look at existing problems from novel perspectives, or exhibit other highly creative qualities. Research that is an incremental advance beyond ongoing research or published data is not considered innovative and is not consistent with the intent of this award mechanism. It is the responsibility of the Principal Investigator (PI) to clearly and explicitly articulate how the proposed research project is innovative in the field of MS research. For the “Correlates of Disease Activity and Progression in MS” Focus Area, applications must demonstrate access to the relevant specimens and/or data of the proposed cohort. Refer to Attachment 9: Letter(s) Confirming Access to Specimens and/or Data for more details. Note for projects involving animal models of MS: Applicants should be prudent in the choice of animal model(s) for their proposed research project. Applicants must justify the relevance of their proposed animal model(s) to the specific aspect of human MS to be studied. New Investigator option: The FY24 MSRP EHDA mechanism encourages applications from investigators in the early stages of their MS research career. The New Investigator option is designed to support the continued development of promising independent investigators that are early in their faculty appointments. Applications from Established Investigators and New Investigators will be peer- and programmatically reviewed in separate groups. PIs applying under the New Investigator option are encouraged to strengthen their applications through collaboration with investigators experienced in MS research and/or possess other relevant expertise as demonstrated by a record of funding and publications.

Category: Science and Technology and other Research and Development.

Who has won Military Medical Research and Development grants before

From fiscal 2021 to 2025, Military Medical Research and Development (12.420) awarded $6.9 billion across 5,470 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.Maryland81$546 million
The Univeristy of Texas M.D. Anderson Cancer CenterTexas139$166 million
The Johns Hopkins UniversityMaryland157$153 million
The Regents of the University of California, San FranciscoCalifornia113$147 million
Duke UniversityNorth Carolina86$123 million

Top states: Maryland ($793 million), California ($751 million), Texas ($598 million), Massachusetts ($586 million), New York ($508 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, HT942526BCRPCREA2, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is HT942524MSRPEHDA still open?

No. It closed on October 7, 2024. A newer notice is open: HT942526BCRPCREA2, closes November 18, 2026 (11 days left).

Who can apply for DoD Multiple Sclerosis, Exploration - Hypothesis Development Award?

Defense Health Agency Contracting Activity - DHACA accepted applications from any type of organization.

What is the deadline for DoD Multiple Sclerosis, Exploration - Hypothesis Development Award?

Closed October 7, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

About $2.0 million in total across about 8 awards.

Who has won Military Medical Research and Development grants before?

The largest recipients over five fiscal years were The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., The Univeristy of Texas M.D. Anderson Cancer Center, The Johns Hopkins University. The program made 5,470 awards worth $6.9 billion in that time.

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