Grants / Department of Defense / Defense Health Agency Contracting Activity - DHACA

HT9425-23-PRARP-TDA: DOD, Peer Reviewed Alzheimer’s, Transforming Diagnosis Award

Closed Closed July 25, 2023 Opportunity HT9425-23-PRARP-TDA ☆ Save

This grant is closed. A newer notice from the same program is open now: DoW Breast Cancer, Clinical Research Extension Award (HT942526BCRPCREA2). Status: Closes November 18, 2026 (11 days left). It is in our archive of Defense Health Agency Contracting Activity - DHACA notices from 2023.

• Total funding$5.0 million
• Expected awards2
• Cost sharingNot required
• Funding typeCooperative Agreement, Grant

Key dates

Who can apply

This opportunity was open to any type of organization.

• Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses, individuals.

Is this a realistic fit?

• Most of the program's money (59% over five years) went to colleges and universities.
• No cost sharing or match is required.

What the grant funds

The TDA is intended to improve diagnosis now. Proposed projects must build knowledge, capacity, and research to reduce important barriers to obtaining a diagnosis, meaningful disease monitoring, and accurate prognosis. Barriers could include but are not limited to cost, patient access and education, clinical implementation, relationship to clinical outcome measures, biomarker validation, diagnosis technologies, lack of longitudinal data to inform prediction/prognosis, health equity barriers including structural and social determinants of health, and more. The investigator must clearly attune their project to provide true benefit to the intended end user – the person with dementia and their families. Key elements of this mechanism are: • Near term applicability: To meet the intent of this mechanism, applications should be focused on addressing diagnosis now. Near term, for the FY23 PRARP TDA, means acceleration within three to five years, focusing on implementation to the community as soon as possible. • Person-focused research: For diagnostic/prognostic outcomes proposed by the research to be successful, those impacted by AD/ADRD need to buy into the approach. This means researchers should design their projects to focus on the people who need the outcomes most, and the best way to do this is to partner with those stakeholders. Therefore, the FY23 PRARP TDA requires all projects to include collaborative community partner approaches. For this mechanism, there is an expectation that the investigator will host a community meeting with a facilitated discussion, to occur within the first three quarters of the period of performance that will help inform the execution of the research. This meeting should involve the intended research population and their community. The intent of this meeting is to gather feedback and input that will inform the execution of the research, optimize and refine research questions and execution therefore as well as help inform the dissemination strategy of the research outcomes. • Prospective recruitment of study participants: To meet the intent of the mechanism, the TDA requires an element of prospective human subjects’ data collection. The proposed project should leverage existing resources where possible; however, the study must ensure the advances proposed by the project aims are representative and applicable to a diverse population.

Category: Science and Technology and other Research and Development.

Applying now

This notice no longer takes applications. Apply under the newer notice, HT942526BCRPCREA2, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.