HT9425-23-ALSRP-CBDA: DOD Amyotrophic Lateral Sclerosis, Clinical Biomarker Development Award
Closed
This grant is closed. A newer notice from the same program is open now: DoW Breast Cancer, Clinical Research Extension Award (HT942526BCRPCREA2). Status: Closes November 18, 2026 (11 days left). It is in our archive of Defense Health Agency Contracting Activity - DHACA notices from 2023.
Defense Health Agency Contracting Activity - DHACA offered grants to any type of organization. It expected to make about 10 awards worth $7.2 million in total. Applications closed on July 13, 2023.
From the official notice on Grants.gov, last changed February 8, 2023. Checked November 7, 2026.
- Total funding$7.2 million
- Expected awards10
- Cost sharingNot required
- Funding typeCooperative Agreement, Grant
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| W81XWH-22-ALSRP-CBDA | March 16, 2022 | Closed July 28, 2022 | Closed |
Key dates
| Posted | February 8, 2023 |
|---|---|
| Deadline | July 13, 2023 |
| Archived by Grants.gov | August 12, 2023 |
Who can apply
This opportunity was open to any type of organization.
- Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"
Is this a realistic fit?
- Most of the program's money (59% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The intent of the FY23 ALSRP Clinical Biomarker Development Award is to support the development of biomarkers to enrich clinical trials in Amyotrophic Lateral Sclerosis (ALS). Biomarker development projects can be relevant to a specific therapy, a class of therapeutics, or to a specific ALS subtype (such as a particular genetic mutation) and do not have to broadly apply to all patients. A description of the biomarker category and intended context of use (COU) in ALS therapeutic development, including regulatory considerations for use in ALS clinical trials or clinical practice, is an important component. Examples of studies appropriate for submission to the FY23 ALSRP Clinical Biomarker Development Award include, but are not limited to: Using patient-based resources to link biosamples to rigorous molecular data. Collecting and analyzing biospecimens as a companion to an anticipated/ongoing clinical trial. Correlation of clinical trial-related data (e.g., biosample analysis, imaging, or epidemiological data) with clinical outcomes or responses to therapies. Strategies to better measure disease progression, including the development or use of digital biomarkers.
Who has won Military Medical Research and Development grants before
From fiscal 2021 to 2025, Military Medical Research and Development (12.420) awarded $6.9 billion across 5,470 grant awards, an average of $1.3 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. | Maryland | 81 | $546 million |
| The Univeristy of Texas M.D. Anderson Cancer Center | Texas | 139 | $166 million |
| The Johns Hopkins University | Maryland | 157 | $153 million |
| The Regents of the University of California, San Francisco | California | 113 | $147 million |
| Duke University | North Carolina | 86 | $123 million |
Applying now
This notice no longer takes applications. Apply under the newer notice, HT942526BCRPCREA2, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is HT9425-23-ALSRP-CBDA still open?
No. It closed on July 13, 2023. A newer notice is open: HT942526BCRPCREA2, closes November 18, 2026 (11 days left).
Who can apply for DOD Amyotrophic Lateral Sclerosis, Clinical Biomarker Development Award?
Defense Health Agency Contracting Activity - DHACA accepted applications from any type of organization.
What is the deadline for DOD Amyotrophic Lateral Sclerosis, Clinical Biomarker Development Award?
Closed July 13, 2023. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
About $7.2 million in total across about 10 awards.
Who has won Military Medical Research and Development grants before?
The largest recipients over five fiscal years were The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., The Univeristy of Texas M.D. Anderson Cancer Center, The Johns Hopkins University. The program made 5,470 awards worth $6.9 billion in that time.