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Grants / Department of Health and Human Services / Health Resources and Services Administration

HRSA-22-091: Early Childhood Developmental Health Systems: Evidence to Impact

Closed Closed May 10, 2022 Opportunity HRSA-22-091

This grant is closed. A newer notice from the same program is open now: Women's Initiative for Screening and Health (WISH) (HRSA-27-072). Status: Closes January 8, 2027 (62 days left). It is in our archive of Health Resources and Services Administration notices from 2022.

Health Resources and Services Administration offered grants of up to $4.3 million to nonprofits, state and local governments, tribes and businesses. It expected to make one award worth $4.3 million in total. Applications closed on May 10, 2022.

From the official notice on Grants.gov, last changed March 29, 2022. Checked November 7, 2026.

Key dates

PostedFebruary 9, 2022
DeadlineMay 10, 2022

Who can apply

This opportunity was open to nonprofits, state and local governments, tribes and businesses.

All 10 applicant types the notice lists

Eligible applicants include any domestic public or private entity, including an Indian tribe or tribal organization (as those terms are defined at 25 U.S.C. § 5304 (formerly cited as 25 U.S.C. § 450b)). See 42 CFR § 51a.3(a). Domestic faith-based and community- based organizations are also eligible to apply. If funded, for-profit organizations are prohibited from earning profit from the federal award (see 45 CFR § 75.216(b)).

More grants for nonprofits, state and local governments, tribes, businesses.

Is this a realistic fit?

What the grant funds

This notice announces the opportunity to apply for funding under the Early Childhood Developmental Health Systems (ECDHS): Evidence to Impact program. The purpose of this program is to advance statewide systems of comprehensive early childhood developmental promotion, screenings, and interventions that improve outcomes and reduce disparities in early developmental health and family well-being for communities with high levels of childhood poverty. These statewide systems will be referred to as early childhood development (ECD) systems throughout this notice of funding opportunity (NOFO). One award will be made, in the form of a cooperative agreement, to establish an Early Childhood Evidence to Impact Center, hereby referred to as the Center. The goals of the Center are to: 1) increase the implementation and evaluation of evidence-informed, equity-focused strategies among states by providing national technical assistance (TA) and supporting the implementation and evaluation of ECD systems-building efforts; and 2) strengthen the evidence base in support of ECD systems-building. In pursuit of these goals, the Center will advance the following objectives: 1. Build, compile, and disseminate the ECD systems evidence base through the development and advancement of a learning agenda. 2. Advance statewide reach and impact of ECD systems through support of implementation and evaluation of evidence-informed, equity-focused strategies in at least three states with Early Childhood Comprehensive Systems (ECCS) initiatives. 3. Increase the number of early childhood and health system leaders in at least 25 states receiving targeted or universal TA, to build capacity to implement and evaluate statewide ECD systems. 4. Improve the adaptability and ease of use of at least 10 resources and/or tools to accelerate ECD systems development. 5. Generate at least one comprehensive model for ECD systems-building for testing and use. This NOFO also describes an opportunity for additional funding to advance the specific strategy of improving delivery of high-quality ECD promotion and support services in pediatric settings. With this funding, the recipient will expand activities under the core ECDHS: Evidence to Impact program to provide national leadership, TA, and coordination in support of the anticipated Transforming Pediatrics for Early Childhood (TPEC) program (see Appendix D and HRSA-22-141 for details). Through this additional TPEC TA Activity, the Center will: 1.

Category: Health.

Who has won Special Projects of Regional and National Significance grants before

From fiscal 2021 to 2025, Special Projects of Regional and National Significance (93.110) awarded $1.4 billion across 842 grant awards, an average of $1.6 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Zero to Three National Center for Infants, Toddlers & FamiliesDistrict of Columbia2$54.3 million
University Hospitals Cleveland Medical CenterOhio1$51.5 million
Children's National Medical CenterDistrict of Columbia1$37.2 million
University of North Carolina at Chapel HillNorth Carolina8$29.1 million
American Academy of PediatricsIllinois8$26.4 million

Top states: District of Columbia ($165 million), California ($82.5 million), Ohio ($75.1 million), Maryland ($73.5 million), Massachusetts ($52.6 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, HRSA-27-072, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is HRSA-22-091 still open?

No. It closed on May 10, 2022. A newer notice is open: HRSA-27-072, closes January 8, 2027 (62 days left).

Who can apply for Early Childhood Developmental Health Systems: Evidence to Impact?

Health Resources and Services Administration accepted applications from nonprofits, state and local governments, tribes and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Early Childhood Developmental Health Systems: Evidence to Impact?

Closed May 10, 2022. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $4.3 million each. About $4.3 million in total for one award.

Who has won Special Projects of Regional and National Significance grants before?

The largest recipients over five fiscal years were Zero to Three National Center for Infants, Toddlers & Families, University Hospitals Cleveland Medical Center, Children's National Medical Center. The program made 842 awards worth $1.4 billion in that time.

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