HR001124S0025: Hermes
Closed
This grant is closed. A newer notice from the same program is open now: Young Faculty Award (YFA) 2027 (DARPARA2701). Status: Closes January 13, 2027 (67 days left). It is in our archive of DARPA - Biological Technologies Office notices from 2024.
DARPA - Biological Technologies Office offered grants to the applicants described in the notice. Applications closed on June 11, 2024.
From the official notice on Grants.gov, last changed May 14, 2024. Checked November 7, 2026.
- Award amountsNot given on Grants.gov
- Cost sharingNot required
- Funding typeCooperative Agreement, Grant, Other, Procurement Contract
Key dates
| Posted | April 19, 2024 |
|---|---|
| Deadline | June 11, 2024 |
| Archived by Grants.gov | July 4, 2024 |
Who can apply
This opportunity was open to the applicants described in the notice.
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
All responsible sources capable of satisfying the Government's needs may submit a proposal that shall be considered by DARPA. See the Eligibility Information section of the BAA for more information.
Is this a realistic fit?
- Most of the program's money (93% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals to develop systemic drug delivery platforms for medical countermeasures (MCMs). The Hermes program is explicitly seeking transformative approaches enabling the development of delivery platforms with systemic biodistribution, exceptional endosomal escape efficiency, and minimal toxicity. Successful proposals will include a detailed description of the proposed delivery platform including 1) screening pipeline, 2) reporter systems for monitoring biodistribution and expression in animal models, 3) methods to monitor immunogenicity/toxicity, and 4) chosen therapeutic cargo and justification. Systemic delivery platforms developed under the Hermes effort will be transferred to U.S. Government stakeholders for further development.
Who has won Research and Technology Development grants before
From fiscal 2021 to 2025, Research and Technology Development (12.910) awarded $1.5 billion across 739 grant awards, an average of $2.1 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| University of Southern California | California | 26 | $84.5 million |
| Clemson University | South Carolina | 2 | $82.2 million |
| Massachusetts Institute of Technology | Massachusetts | 29 | $63.1 million |
| Regents of the University of Michigan | Michigan | 21 | $59.6 million |
| The Regents of the University of California, San Francisco | California | 5 | $44.4 million |
Applying now
This notice no longer takes applications. Apply under the newer notice, DARPARA2701, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is HR001124S0025 still open?
No. It closed on June 11, 2024. A newer notice is open: DARPARA2701, closes January 13, 2027 (67 days left).
Who can apply for Hermes?
DARPA - Biological Technologies Office accepted applications from the applicants described in the notice. The notice adds further conditions, so read its eligibility section.
What is the deadline for Hermes?
Closed June 11, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.
Who has won Research and Technology Development grants before?
The largest recipients over five fiscal years were University of Southern California, Clemson University, Massachusetts Institute of Technology. The program made 739 awards worth $1.5 billion in that time.