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Grants / Department of Defense / DARPA - Biological Technologies Office

HR001122S0044: Smart Non-invasive Assays of Physiology (SNAP)

Closed Closed September 15, 2022 Opportunity HR001122S0044

This grant is closed. A newer notice from the same program is open now: Young Faculty Award (YFA) 2027 (DARPARA2701). Status: Closes January 13, 2027 (67 days left). It is in our archive of DARPA - Biological Technologies Office notices from 2022.

DARPA - Biological Technologies Office offered grants to the applicants described in the notice. Applications closed on September 15, 2022.

From the official notice on Grants.gov, last changed September 1, 2022. Checked November 7, 2026.

Key dates

PostedJuly 12, 2022
DeadlineSeptember 15, 2022
Archived by Grants.govOctober 15, 2022

Who can apply

This opportunity was open to the applicants described in the notice.

All responsible sources capable of satisfying the Government's needs may submit a proposal that shall be considered by DARPA. See the Eligibility Information section of the BAA for more information.

Is this a realistic fit?

What the grant funds

The Smart Non-invasive Assays of Physiology (SNAP) program aims to develop a portable, multi-omic, multiplexed sensor prototype capable of implementing models that assess warfighter physiological states based on molecular biomarkers. SNAP will be rapidly adaptable to diverse DoD end user needs for readiness assessment and training, providing warfighters with a personalized view into their performance state. Recent research demonstrates that bodily fluids such as saliva carry signatures of physiological states in both health and disease, and in particular, physical and cognitive exertion. Ultimately, models of readiness or other physiological states will require point-of-person tools to process samples, analyze different classes of biomarkers in a single device, and implement these predictive models in real-world settings and on operationally relevant time frames.

Category: Science and Technology and other Research and Development.

Who has won Research and Technology Development grants before

From fiscal 2021 to 2025, Research and Technology Development (12.910) awarded $1.5 billion across 739 grant awards, an average of $2.1 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
University of Southern CaliforniaCalifornia26$84.5 million
Clemson UniversitySouth Carolina2$82.2 million
Massachusetts Institute of TechnologyMassachusetts29$63.1 million
Regents of the University of MichiganMichigan21$59.6 million
The Regents of the University of California, San FranciscoCalifornia5$44.4 million

Top states: California ($334 million), Massachusetts ($188 million), New York ($103 million), Pennsylvania ($87.8 million), Illinois ($83.3 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, DARPARA2701, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is HR001122S0044 still open?

No. It closed on September 15, 2022. A newer notice is open: DARPARA2701, closes January 13, 2027 (67 days left).

Who can apply for Smart Non-invasive Assays of Physiology (SNAP)?

DARPA - Biological Technologies Office accepted applications from the applicants described in the notice. The notice adds further conditions, so read its eligibility section.

What is the deadline for Smart Non-invasive Assays of Physiology (SNAP)?

Closed September 15, 2022. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has won Research and Technology Development grants before?

The largest recipients over five fiscal years were University of Southern California, Clemson University, Massachusetts Institute of Technology. The program made 739 awards worth $1.5 billion in that time.

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