HR001121S0037: Assessing Immune Memory (AIM)
Closed
This grant is closed. A newer notice from the same program is open now: Young Faculty Award (YFA) 2027 (DARPARA2701). Status: Closes January 13, 2027 (67 days left). It is in our archive of DARPA - Biological Technologies Office notices from 2021.
DARPA - Biological Technologies Office offered grants to the applicants described in the notice. Applications closed on October 26, 2021.
From the official notice on Grants.gov, last changed September 7, 2021. Checked November 7, 2026.
- Award amountsNot given on Grants.gov
- Cost sharingNot required
- Funding typeCooperative Agreement, Other, Procurement Contract
Key dates
| Posted | August 20, 2021 |
|---|---|
| Deadline | October 26, 2021 |
| Archived by Grants.gov | November 25, 2021 |
Who can apply
This opportunity was open to the applicants described in the notice.
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
All responsible sources capable of satisfying the Government's needs may submit a proposal that shall be considered by DARPA. See the Eligibility Information section of the BAA for more information.
Is this a realistic fit?
- Most of the program's money (93% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
Military service members rely on effective vaccination for the prevention of communicable disease as well as to guard against biothreat exposure. Many current vaccines lack durability (i.e., do not provide effective protection over long periods of time), and there are multiple pathogens and threats that lack prophylactic options altogether. It is currently impossible to predict vaccine durability from early response profiles, largely owing to ignorance of mechanisms underlying immune memory as well as an inability to measure the cellular contributors that invoke long-lasting immune protection. Formation of immune memory is a complex physiological process characterized by a diverse array of cellular interactions and signaling processes. AIM seeks to develop a platform capability to predict immune memory informed by a systems-level view of the host response to vaccination and its mechanisms.
Who has won Research and Technology Development grants before
From fiscal 2021 to 2025, Research and Technology Development (12.910) awarded $1.5 billion across 739 grant awards, an average of $2.1 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| University of Southern California | California | 26 | $84.5 million |
| Clemson University | South Carolina | 2 | $82.2 million |
| Massachusetts Institute of Technology | Massachusetts | 29 | $63.1 million |
| Regents of the University of Michigan | Michigan | 21 | $59.6 million |
| The Regents of the University of California, San Francisco | California | 5 | $44.4 million |
Applying now
This notice no longer takes applications. Apply under the newer notice, DARPARA2701, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is HR001121S0037 still open?
No. It closed on October 26, 2021. A newer notice is open: DARPARA2701, closes January 13, 2027 (67 days left).
Who can apply for Assessing Immune Memory (AIM)?
DARPA - Biological Technologies Office accepted applications from the applicants described in the notice. The notice adds further conditions, so read its eligibility section.
What is the deadline for Assessing Immune Memory (AIM)?
Closed October 26, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.
Who has won Research and Technology Development grants before?
The largest recipients over five fiscal years were University of Southern California, Clemson University, Massachusetts Institute of Technology. The program made 739 awards worth $1.5 billion in that time.