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EPA-G2022-STAR-A2: Early Career: Development of Innovative Approaches to Assess the Toxicity of Chemical Mixtures

Closed Closed December 8, 2021 Opportunity EPA-G2022-STAR-A2

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of Environmental Protection Agency notices from 2021.

Environmental Protection Agency offered grants of up to $600,000 to the applicants described in the notice. It expected to make about 2 awards worth $4.2 million in total. Applications closed on December 8, 2021.

From the official notice on Grants.gov, last changed October 8, 2021. Checked November 7, 2026.

Key dates

PostedOctober 8, 2021
DeadlineDecember 8, 2021
Archived by Grants.govJanuary 7, 2022

Who can apply

This opportunity was open to the applicants described in the notice.

Please see Section III of the announcement for eligibility information.

Is this a realistic fit?

What the grant funds

This Request for Applications (RFA) solicits research focused on the development and evaluation of innovative methods and approaches to inform human health risk assessment of environmental chemical mixtures. Because most of the human chemical body burden involves concurrent or sequential exposures to mixtures of chemicals, methods to make better-informed, timelier evaluations of chemical mixtures of known, or partially-known, composition have long been needed. A challenge in conducting mixtures assessment is the lack of useful hazard and dose response data and other information on chemical mixtures. Potential chemical mixtures exposures of public health concern typically encountered in environmental media may include classes or subclasses of compounds (for example, per- and polyfluoroalkyl substances [PFAS], phthalates, polycyclic aromatic hydrocarbons [PAHs], disinfection by-products [DBPs]), or any other well-characterized mixtures. Applications are being sought that propose approaches and strategies that integrate in vitro, in silico, and/or non-mammalian in vivo methods that can contribute to decision-making science associated with toxicity evaluation and human health assessment of chemical mixtures.

Category: Environment.

Who has won Science To Achieve Results (STAR) Research Program grants before

From fiscal 2021 to 2025, Science To Achieve Results (STAR) Research Program (66.509) awarded $125 million across 117 grant awards, an average of $1.1 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Regents of the University of CaliforniaCalifornia5$5.0 million
Texas Tech University SystemTexas2$4.1 million
University of North Carolina at Chapel HillNorth Carolina4$4.0 million
University of WashingtonWashington3$3.7 million
University of California, DavisCalifornia3$3.5 million

Top states: California ($23.3 million), North Carolina ($8.5 million), Texas ($7.9 million), New York ($7.3 million), Georgia ($6.0 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is EPA-G2022-STAR-A2 still open?

No. It closed on December 8, 2021.

Who can apply for Early Career: Development of Innovative Approaches to Assess the Toxicity of Chemical Mixtures?

Environmental Protection Agency accepted applications from the applicants described in the notice. The notice adds further conditions, so read its eligibility section.

What is the deadline for Early Career: Development of Innovative Approaches to Assess the Toxicity of Chemical Mixtures?

Closed December 8, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $600,000 each. About $4.2 million in total across about 2 awards.

Who has won Science To Achieve Results (STAR) Research Program grants before?

The largest recipients over five fiscal years were The Regents of the University of California, Texas Tech University System, University of North Carolina at Chapel Hill. The program made 117 awards worth $125 million in that time.

Similar open grants