DE-FOA-0003530: Research, Development, and Training in Isotope Production
Closed
This grant is closed. A newer notice from the same program is open now: Genesis Mission Graduate Fellowship Pilot (DE-FOA-0003673). Status: Closes January 12, 2027 (66 days left). It is in our archive of Office of Science notices from 2025.
Office of Science offered grants of up to $1.5 million (at least $200,000) to the applicants described in the notice. Applications closed on April 17, 2025.
From the official notice on Grants.gov, last changed January 17, 2025. Checked November 7, 2026.
- Award ceiling$1.5 million
- Award floor$200,000
- Cost sharingNot required
- Funding typeGrant, Other
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| DE-FOA-0003063 | May 5, 2023 | Closed July 5, 2023 | Closed |
Key dates
| Posted | January 17, 2025 |
|---|---|
| Deadline | April 17, 2025 |
| Archived by Grants.gov | May 17, 2025 |
Who can apply
This opportunity was open to the applicants described in the notice.
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Please refer to page 3 of the NOFO.
Is this a realistic fit?
- Past Office of Science Financial Assistance Program awards averaged $1.2 million; this notice allows up to $1.5 million per award.
- Most of the program's money (69% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
Isotopes are high-priority commodities of strategic importance for the Nation and are essential in medical diagnosis and treatment, discovery science, national security, industrial processes, advanced manufacturing, space exploration, communications, biology, archaeology, quantum information science, clean energy, environmental science, and other fields. Isotopes can directly enable emerging technologies and contribute to the economic, technical, and scientific strength of the United States. The DOE Office of Science Program for Isotope R&D and Production (also referred to as the DOE Isotope Program or DOE IP) routinely funds research and development (R&D) in isotope science to advance fundamental understanding and develop cutting edge and efficient technologies for enriching, producing, processing, recycling, and purifying radioactive and stable isotopes in short supply. This Notice of Funding Opportunity (NOFO) is narrowly focused on topics involving AI/ML, enhanced processing chemistry used in matter phase changes, and separation science. Applications incorporating effective ways to train the next generation of personnel with essential knowledge and skills related to the production, processing, and purification of radioactive and enriched stable isotopes are strongly encouraged.
Who has won Office of Science Financial Assistance Program grants before
From fiscal 2021 to 2025, Office of Science Financial Assistance Program (81.049) awarded $7.7 billion across 6,205 grant awards, an average of $1.2 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Michigan State University Foundation | Michigan | 84 | $573 million |
| General Atomics | California | 30 | $495 million |
| University of Wisconsin System | Wisconsin | 101 | $275 million |
| Massachusetts Institute of Technology | Massachusetts | 118 | $238 million |
| University of Illinois | Illinois | 61 | $201 million |
Applying now
This notice no longer takes applications. Apply under the newer notice, DE-FOA-0003673, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is DE-FOA-0003530 still open?
No. It closed on April 17, 2025. A newer notice is open: DE-FOA-0003673, closes January 12, 2027 (66 days left).
Who can apply for Research, Development, and Training in Isotope Production?
Office of Science accepted applications from the applicants described in the notice. The notice adds further conditions, so read its eligibility section.
What is the deadline for Research, Development, and Training in Isotope Production?
Closed April 17, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $1.5 million each.
Who has won Office of Science Financial Assistance Program grants before?
The largest recipients over five fiscal years were Michigan State University Foundation, General Atomics, University of Wisconsin System. The program made 6,205 awards worth $7.7 billion in that time.