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Grants / Department of Energy / Advanced Research Projects Agency Energy

DE-FOA-0003505: CATALYTIC APPLICATION TESTING FOR ACCELERATED LEARNING CHEMISTRIES VIA HIGH-THROUGHPUT EXPERIMENTATION AND MODELING EFFICIENTLY (CATALCHEM-E)

Closed Closed February 25, 2026 Opportunity DE-FOA-0003505

This grant is closed. A newer notice from the same program is open now: Unlocking New Levels of Output and Capacity for Key Subsurface Resources (UNLOCK) (DE-FOA-0003630). Status: Closes November 20, 2026 (13 days left). It is in our archive of Advanced Research Projects Agency Energy notices from 2024.

Advanced Research Projects Agency Energy offered grants of up to $3.5 million (at least $2.5 million) to any type of organization. It expected to make about 12 awards worth $35.0 million in total. Applications closed on February 25, 2026.

From the official notice on Grants.gov, last changed February 10, 2026. Checked November 7, 2026.

Key dates

PostedNovember 14, 2024
DeadlineFebruary 25, 2026
Archived by Grants.govMay 25, 2026

Who can apply

This opportunity was open to any type of organization.

See Section II.A. of the NOFO

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses, individuals.

Is this a realistic fit?

What the grant funds

This is modification 03 to the NOFO: • Removed indirect cost cap at 15% of Total Project Costs (Section I.G.15). NOFO Number: DE-FOA-0003505 - CATALYTIC APPLICATION TESTING FOR ACCELERATED LEARNING CHEMISTRIES VIA HIGH-THROUGHPUT EXPERIMENTATION AND MODELING EFFICIENTLY (CATALCHEM-E) To obtain a copy of the Notice of Funding Opportunity (NOFO) please go to ARPA-E eXCHANGE at https://arpa-e-foa.energy.gov. To apply to this NOFO, Applicants must register with and submit application materials through ARPA-E eXCHANGE (https://arpa-e-foa.energy.gov/Registration.aspx). For detailed guidance on using ARPA-E eXCHANGE, please refer to the ARPA-E eXCHANGE User Guide (https://arpa-e-foa.energy.gov/Manuals.aspx). ARPA-E will not review or consider application materials submitted through other means. For problems with ARPA-E eXCHANGE, email ExchangeHelp@hq.doe.gov (with NOFO name and number in the subject line). Questions about this NOFO? Check the Frequently Asked Questions available at http://arpa-e.energy.gov/faq. For questions that have not already been answered, email ARPA-E-CO@hq.doe.gov. Agency Overview: The Advanced Research Projects Agency – Energy (ARPA-E), an organization within the Department of Energy (DOE), is chartered by Congress in the America COMPETES Act of 2007 (P.L. 110-69), as amended by the America COMPETES Reauthorization Act of 2010 (P.L. 111-358), as further amended by the Energy Act of 2020 (P.L. 116-260): “(A) to enhance the economic and energy security of the United States through the development of energy technologies that— (i) reduce imports of energy from foreign sources; (ii) reduce energy-related emissions, including greenhouse gases; (iii) improve the energy efficiency of all economic sectors; (iv) provide transformative solutions to improve the management, clean-up, and disposal of radioactive waste and spent nuclear fuel; and (v) improve the resilience, reliability, and security of infrastructure to produce, deliver, and store energy; and (B) to ensure that the United States maintains a technological lead in developing and deploying advanced energy technologies.” ARPA-E issues this Notice of Funding Opportunity (NOFO) under its authorizing statute codified at 42 U.S.C. § 16538. The NOFO and any cooperative agreements or grants made under this NOFO are subject to 2 C.F.R. Part 200 as supplemented by 2 C.F.R. Part 910.

Category: Opportunity Zone Benefits, Science and Technology and other Research and Development.

Who has won Advanced Research Projects Agency - Energy grants before

From fiscal 2021 to 2025, Advanced Research Projects Agency - Energy (81.135) awarded $1.4 billion across 729 grant awards, an average of $1.9 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
RTX CorporationConnecticut15$33.9 million
Massachusetts Institute of TechnologyMassachusetts16$31.4 million
BWXT Advanced Technologies LLCVirginia1$30.9 million
Ge Vernova Operations LLCNew York8$26.4 million
University of Maryland, College ParkMaryland11$23.6 million

Top states: California ($231 million), Massachusetts ($148 million), Texas ($122 million), New York ($107 million), Maryland ($82.5 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, DE-FOA-0003630, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is DE-FOA-0003505 still open?

No. It closed on February 25, 2026. A newer notice is open: DE-FOA-0003630, closes November 20, 2026 (13 days left).

Who can apply for CATALYTIC APPLICATION TESTING FOR ACCELERATED LEARNING CHEMISTRIES VIA HIGH-THROUGHPUT EXPERIMENTATION AND MODELING EFFICIENTLY (CATALCHEM-E)?

Advanced Research Projects Agency Energy accepted applications from any type of organization. The notice adds further conditions, so read its eligibility section.

What is the deadline for CATALYTIC APPLICATION TESTING FOR ACCELERATED LEARNING CHEMISTRIES VIA HIGH-THROUGHPUT EXPERIMENTATION AND MODELING EFFICIENTLY (CATALCHEM-E)?

Closed February 25, 2026. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $3.5 million each. About $35.0 million in total across about 12 awards.

Who has won Advanced Research Projects Agency - Energy grants before?

The largest recipients over five fiscal years were RTX Corporation, Massachusetts Institute of Technology, BWXT Advanced Technologies LLC. The program made 729 awards worth $1.4 billion in that time.

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