DE-FOA-0003264: Advancements in Artificial Intelligence for Science
Closed
This grant is closed. A newer notice from the same program is open now: Genesis Mission Graduate Fellowship Pilot (DE-FOA-0003673). Status: Closes January 12, 2027 (66 days left). It is in our archive of Office of Science notices from 2024.
Office of Science offered grants of up to $7.0 million (at least $750,000) to any type of organization. It expected to make $36.0 million in total. Applications closed on May 22, 2024.
From the official notice on Grants.gov, last changed May 10, 2024. Checked November 7, 2026.
- Award ceiling$7.0 million
- Award floor$750,000
- Total funding$36.0 million
- Cost sharingNot required
- Funding typeCooperative Agreement, Grant, Other
Key dates
| Posted | February 13, 2024 |
|---|---|
| Deadline | May 22, 2024 |
| Archived by Grants.gov | June 20, 2024 |
Who can apply
This opportunity was open to any type of organization.
- Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"
All types of applicants are eligible to apply, except nonprofit organizations described in section 501(c)(4) of the Internal Revenue Code of 1986 that engaged in lobbying activities after December 31, 1995.
Is this a realistic fit?
- Past Office of Science Financial Assistance Program awards averaged $1.2 million; this notice allows up to $7.0 million per award.
- Most of the program's money (69% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The DOE SC program in Advanced Scientific Computing Research (ASCR) hereby announces its interest in basic computer science and applied mathematics research in the fundamentals of Artificial Intelligence (AI) for science. Specifically, advancements in this area are sought that can enable the development of: · Foundation models for computational science; · Automated scientific workflows and laboratories; · Scientific programming and scientific-knowledge-management systems; · Federated and privacy-preserving training for foundation and other AI models for science; and · Energy-efficient AI algorithms and hardware for science. The development of new AI techniques applicable to multiple scientific domains can accelerate progress, increase transparency, and open new areas of exploration across the scientific enterprise. SUPPLEMENTARY INFORMATION AI is one of the most powerful technologies of our time[1] and DOE is at the forefront of research and development in AI technologies for enabling scientific discovery and innovation. Core components of the scientific method remain unchanged: Observation, Hypothesis, Experiments, and Analysis. However, DOE recognizes that abundant sources of data, high-performance computing (HPC) and networking, energy-efficient algorithms, and AI-related technologies can be harnessed to significantly accelerate and expand the impact of scientific research. The breadth of applications spans climate science, cybersecurity and electric grid resilience, biotechnology, microelectronics, disaster response, and beyond. Research to address national priorities will require advances and AI innovations in high-level capabilities such as: monitoring and predicting the onset of real-world anomalies and extreme events; adaptive strategies to control the real-time behavior of complex systems, infrastructure, and processes; approaches for the optimal development and design of physical systems; decision-support for planning, risk, and policy formulation; and tools that synthesize scientific knowledge and accelerate the design, manufacturing, testing, and optimization of new technologies. The focus of ASCR research and development investments is on the underlying approaches for AI-enhanced scientific and engineering capabilities and to significantly transform the scientific method for accelerated discovery and innovation. Realizing the next generation of AI for science will require innovations in both hardware and algorithms.
Who has won Office of Science Financial Assistance Program grants before
From fiscal 2021 to 2025, Office of Science Financial Assistance Program (81.049) awarded $7.7 billion across 6,205 grant awards, an average of $1.2 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Michigan State University Foundation | Michigan | 84 | $573 million |
| General Atomics | California | 30 | $495 million |
| University of Wisconsin System | Wisconsin | 101 | $275 million |
| Massachusetts Institute of Technology | Massachusetts | 118 | $238 million |
| University of Illinois | Illinois | 61 | $201 million |
Applying now
This notice no longer takes applications. Apply under the newer notice, DE-FOA-0003673, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is DE-FOA-0003264 still open?
No. It closed on May 22, 2024. A newer notice is open: DE-FOA-0003673, closes January 12, 2027 (66 days left).
Who can apply for Advancements in Artificial Intelligence for Science?
Office of Science accepted applications from any type of organization. The notice adds further conditions, so read its eligibility section.
What is the deadline for Advancements in Artificial Intelligence for Science?
Closed May 22, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $7.0 million each. About $36.0 million in total.
Who has won Office of Science Financial Assistance Program grants before?
The largest recipients over five fiscal years were Michigan State University Foundation, General Atomics, University of Wisconsin System. The program made 6,205 awards worth $7.7 billion in that time.