DE-FOA-0002532: Advancing Novel Medical Isotopes for Clinical Trials
Closed
This grant is closed. A newer notice from the same program is open now: Genesis Mission Graduate Fellowship Pilot (DE-FOA-0003673). Status: Closes January 12, 2027 (66 days left). It is in our archive of Office of Science notices from 2021.
Office of Science offered grants of up to $500,000 (at least $100,000) to colleges and universities. Applications closed on July 23, 2021.
From the official notice on Grants.gov, last changed June 1, 2021. Checked November 7, 2026.
- Award ceiling$500,000
- Award floor$100,000
- Cost sharingNot required
- Funding typeGrant
Key dates
| Posted | June 1, 2021 |
|---|---|
| Deadline | July 23, 2021 |
| Archived by Grants.gov | August 22, 2021 |
Who can apply
This opportunity was open to colleges and universities.
- Public and State controlled institutions of higher education
- Private institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Refer to page 9 of the FOA.
Is this a realistic fit?
- Past Office of Science Financial Assistance Program awards averaged $1.2 million; this notice allows up to $500,000 per award.
- Most of the program's money (69% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The DOE SC program in Isotope R&D and Production (DOE IP) hereby announces its interest in receiving applications for research to facilitate, streamline, and accelerate the translation of novel radioisotopes and their associated chelating agents and linker/ligands, for both diagnosis and treatment, from the laboratory bench to evaluation for potential usage in clinical and pre-clinical trials. Evaluating these materials for use in clinical and pre-clinical trials is beyond the scope of this FOA as well as outside the mission of the DOE IP: Applications requesting support for such evaluations will be declined without merit review. Successful applications would benefit the public by leveraging the scientific and technical capabilities of existing facilities at institutions of higher education, non-profit research institutions, and DOE/National Nuclear Security Administration (NNSA) National Laboratories to accelerate the development process for new diagnostic and therapeutic agents. Applications focused on aspects of isotope R&D not associated with translational research are outside the scope of this FOA and will be declined without merit review. Applications are restricted to recently-developed medical isotopes by the DOE IP (listed on the next page) but are not restricted in chelator/ligand technology. Applications incorporating effective ways to train personnel with essential knowledge and skills related to the production, processing, purification, and distribution of enriched stable and radioactive isotopes are strongly encouraged. While this FOA is administered by the DOE IP, the assessment of submitted proposals will be in coordination with the National Institutes of Health.
Who has won Office of Science Financial Assistance Program grants before
From fiscal 2021 to 2025, Office of Science Financial Assistance Program (81.049) awarded $7.7 billion across 6,205 grant awards, an average of $1.2 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Michigan State University Foundation | Michigan | 84 | $573 million |
| General Atomics | California | 30 | $495 million |
| University of Wisconsin System | Wisconsin | 101 | $275 million |
| Massachusetts Institute of Technology | Massachusetts | 118 | $238 million |
| University of Illinois | Illinois | 61 | $201 million |
Applying now
This notice no longer takes applications. Apply under the newer notice, DE-FOA-0003673, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is DE-FOA-0002532 still open?
No. It closed on July 23, 2021. A newer notice is open: DE-FOA-0003673, closes January 12, 2027 (66 days left).
Who can apply for Advancing Novel Medical Isotopes for Clinical Trials?
Office of Science accepted applications from colleges and universities. The notice adds further conditions, so read its eligibility section.
What is the deadline for Advancing Novel Medical Isotopes for Clinical Trials?
Closed July 23, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $500,000 each.
Who has won Office of Science Financial Assistance Program grants before?
The largest recipients over five fiscal years were Michigan State University Foundation, General Atomics, University of Wisconsin System. The program made 6,205 awards worth $7.7 billion in that time.