DE-FOA-0002381: FY2021 SBIR/STTR Phase II Release 2
Closed
This grant is closed. A newer notice from the same program is open now: Genesis Mission Graduate Fellowship Pilot (DE-FOA-0003673). Status: Closes January 12, 2027 (66 days left). It is in our archive of Office of Science notices from 2021.
Office of Science offered grants of up to $1.6 million (at least $1) to small businesses. It expected to make about 100 awards worth $115 million in total. Applications closed on May 14, 2021.
From the official notice on Grants.gov, last changed May 12, 2021. Checked November 7, 2026.
- Award ceiling$1.6 million
- Award floor$1
- Total funding$115 million
- Expected awards100
- Cost sharingNot required
- Funding typeCooperative Agreement, Grant
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| DE-FOA-0002572 | February 28, 2022 | Closed April 29, 2022 | Closed |
Key dates
| Posted | March 4, 2021 |
|---|---|
| Deadline | May 14, 2021 |
| Archived by Grants.gov | July 20, 2021 |
Who can apply
This opportunity was open to small businesses.
- Small businesses
Is this a realistic fit?
- Past Office of Science Financial Assistance Program awards averaged $1.2 million; this notice allows up to $1.6 million per award.
- Most of the program's money (69% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The DOE invites eligible Phase I and Phase II awardees to apply for Phase II awards (grants and cooperative agreements) (both initial and second and third) under this Funding Opportunity Announcement (FOA). Topic descriptions for this FOA can be found on the DOE SBIR/STTR web site at https://science.osti.gov/sbir/Funding-Opportunities.
Who has won Office of Science Financial Assistance Program grants before
From fiscal 2021 to 2025, Office of Science Financial Assistance Program (81.049) awarded $7.7 billion across 6,205 grant awards, an average of $1.2 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Michigan State University Foundation | Michigan | 84 | $573 million |
| General Atomics | California | 30 | $495 million |
| University of Wisconsin System | Wisconsin | 101 | $275 million |
| Massachusetts Institute of Technology | Massachusetts | 118 | $238 million |
| University of Illinois | Illinois | 61 | $201 million |
Applying now
This notice no longer takes applications. Apply under the newer notice, DE-FOA-0003673, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is DE-FOA-0002381 still open?
No. It closed on May 14, 2021. A newer notice is open: DE-FOA-0003673, closes January 12, 2027 (66 days left).
Who can apply for FY2021 SBIR/STTR Phase II Release 2?
Office of Science accepted applications from small businesses.
What is the deadline for FY2021 SBIR/STTR Phase II Release 2?
Closed May 14, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $1.6 million each. About $115 million in total across about 100 awards.
Who has won Office of Science Financial Assistance Program grants before?
The largest recipients over five fiscal years were Michigan State University Foundation, General Atomics, University of Wisconsin System. The program made 6,205 awards worth $7.7 billion in that time.