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Grants / Department of Energy / Office of Science

DE-FOA-0002381: FY2021 SBIR/STTR Phase II Release 2

Closed Closed May 14, 2021 Opportunity DE-FOA-0002381

This grant is closed. A newer notice from the same program is open now: Genesis Mission Graduate Fellowship Pilot (DE-FOA-0003673). Status: Closes January 12, 2027 (66 days left). It is in our archive of Office of Science notices from 2021.

Office of Science offered grants of up to $1.6 million (at least $1) to small businesses. It expected to make about 100 awards worth $115 million in total. Applications closed on May 14, 2021.

From the official notice on Grants.gov, last changed May 12, 2021. Checked November 7, 2026.

Other notices with this title

Office of Science has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
DE-FOA-0002572February 28, 2022Closed April 29, 2022Closed

Key dates

PostedMarch 4, 2021
DeadlineMay 14, 2021
Archived by Grants.govJuly 20, 2021

Who can apply

This opportunity was open to small businesses.

More grants for small businesses.

Is this a realistic fit?

What the grant funds

The DOE invites eligible Phase I and Phase II awardees to apply for Phase II awards (grants and cooperative agreements) (both initial and second and third) under this Funding Opportunity Announcement (FOA). Topic descriptions for this FOA can be found on the DOE SBIR/STTR web site at https://science.osti.gov/sbir/Funding-Opportunities.

Category: Science and Technology and other Research and Development.

Who has won Office of Science Financial Assistance Program grants before

From fiscal 2021 to 2025, Office of Science Financial Assistance Program (81.049) awarded $7.7 billion across 6,205 grant awards, an average of $1.2 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Michigan State University FoundationMichigan84$573 million
General AtomicsCalifornia30$495 million
University of Wisconsin SystemWisconsin101$275 million
Massachusetts Institute of TechnologyMassachusetts118$238 million
University of IllinoisIllinois61$201 million

Top states: California ($1.5 billion), Michigan ($707 million), Massachusetts ($509 million), Illinois ($461 million), New York ($445 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, DE-FOA-0003673, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is DE-FOA-0002381 still open?

No. It closed on May 14, 2021. A newer notice is open: DE-FOA-0003673, closes January 12, 2027 (66 days left).

Who can apply for FY2021 SBIR/STTR Phase II Release 2?

Office of Science accepted applications from small businesses.

What is the deadline for FY2021 SBIR/STTR Phase II Release 2?

Closed May 14, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $1.6 million each. About $115 million in total across about 100 awards.

Who has won Office of Science Financial Assistance Program grants before?

The largest recipients over five fiscal years were Michigan State University Foundation, General Atomics, University of Wisconsin System. The program made 6,205 awards worth $7.7 billion in that time.

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