Grants / Department of Health and Human Services / Centers for Disease Control - NCIPC

CDC-RFA-CE-26-0208: Drug-Free Communities (DFC) Support Program - (Year 6 - FY25 Cohort)

Closed Closed February 12, 2026 Opportunity CDC-RFA-CE-26-0208 ☆ Save

This grant is closed. A newer notice from the same program is forecast: Drug-Free Communities (DFC) Support Program – Competing Continuation (Year 6) (CDC-RFA-CE22-22050601CONT27). Status: Expected deadline March 31, 2027. It is in our archive of Centers for Disease Control - NCIPC notices from 2025.

• Award ceiling$125,000
• Total funding$50.0 million
• Expected awards80
• Cost sharingRequired
• Funding typeGrant

Key dates

Who can apply

This opportunity was open to any type of organization.

Eligible applicants are community-based coalitions addressing youth substance use that have previously received a DFC grant (Year 1–5), have experienced a lapse in funding, or have concluded the first five-year funding cycle and are applying for a second five-year funding cycle. Applicants must be a nonprofit (as defined by the IRS as a 501(c) organization); or an entity that the Administrator determines to be appropriate; or part of, or is associated with an established legally recognized domestic, public or private nonprofit organization. For example, state and local governments, federally recognized tribes, state-recognized tribes, urban Indian organizations (as defined in Pub. L. No. 94-437), public or private universities and colleges, professional associations, voluntary organizations, self-help groups, consumer and provider services-oriented constituency groups, community- and faith-based organizations, and tribal organizations. (Pub. L. No. 114-198 Sec 103). For the purposes of this NOFO and the DFC Support Program, a coalition is defined as a community-based formal arrangement for cooperation and collaboration among groups or sectors of a community in which each group retains its identity, but all agree to work together toward a common goal of building a safe, healthy, and drug-free community. In furtherance of the Trump Administration's Statement of Drug Policy Priorities, the DFC Support Program is committed to protecting American youth from the dangers of drug use. DFC Support Program applicants are expected to support applicable Executive Orders, including but not limited to: Executive Order 14168: Defending Women From Gender Ideology Extremism and Restoring Biological Truth to the Federal Government, Executive Order 14159: Protecting the American People from Invasion, Executive Order 14173: Ending Illegal Discrimination and Restoring Merit-Based Opportunity, Executive Order 13768: Enhancing Public Safety in the Interior of the United States, Executive Order 14182: Enforcing the Hyde Amendment.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses, individuals.

Is this a realistic fit?

• Past Drug-Free Communities Support Program Grants awards averaged $312,548; this notice allows up to $125,000 per award.
• Most of the program's money (71% over five years) went to nonprofits.
• The notice requires cost sharing or matching funds, so you must contribute part of the project cost.

What the grant funds

The Drug-Free Communities (DFC) Support Program was created by the Drug-Free Communities Act of 1997 (Public Law 105-20). The Executive Office of the President, Office of National Drug Control Policy (ONDCP), and the Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC), National Center for Injury Prevention and Control (NCIPC) are accepting applications for Fiscal Year (FY) 2026 Drug-Free Communities (DFC) Support Program Grants. The purpose of the DFC Support Program is to establish and strengthen collaborations to support the efforts of community coalitions working to prevent and reduce substance use among youth. By statute, the DFC Support Program has two goals: 1) Establish and strengthen the collaboration among communities, public and private non-profit agencies, as well as federal, state, local, and tribal governments to support the efforts of community coalitions working to prevent and reduce substance use among youth (individuals 18 years of age and younger). 2) Reduce substance use among youth and, over time, reduce substance use among adults by addressing the factors in a community that increases the risk of substance use and promoting the factors that minimize the risk of substance use. This funding opportunity will fund applicants who have concluded the first (Year 1 – 5) funding cycle or have experienced a lapse in funding.

Category: Health.

Applying now

This notice no longer takes applications. Apply under the newer notice, CDC-RFA-CE22-22050601CONT27, which is forecast.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.