NSF 24-561: Foundations for Digital Twins as Catalyzers of Biomedical Technological Innovation
Closed
This grant is closed. A newer notice from the same program is open now: Major Research Instrumentation Program: (MRI) (NSF 27-500). Status: Closes January 29, 2027 (83 days left). It is in our archive of U.S. National Science Foundation notices from 2024.
U.S. National Science Foundation offered grants to the applicants described in the notice. It expected to make about 10 awards worth $5.0 million in total. Applications closed on May 4, 2026.
From the official notice on Grants.gov, last changed May 28, 2025. Checked November 7, 2026.
- Total funding$5.0 million
- Expected awards10
- Cost sharingNot required
- Funding typeGrant
Key dates
| Posted | March 23, 2024 |
|---|---|
| Deadline | May 4, 2026 |
| Archived by Grants.gov | June 3, 2026 |
Who can apply
This opportunity was open to the applicants described in the notice.
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
*Who May Submit Proposals: Proposals may only be submitted by the following: -Institutions of Higher Education (IHEs): Two- and four-year IHEs (including community colleges) accredited in, and having a campus located in the US, acting on behalf of their faculty members. Special Instructions for International Branch Campuses of US IHEs: If the proposal includes funding to be provided to an international branch campus of a US institution of higher education (including through use of sub-awards and consultant arrangements), the proposer must explain the benefit(s) to the project of performance at the international branch campus, and justify why the project activities cannot be performed at the US campus.
Is this a realistic fit?
- Most of the money in the 3 programs behind this notice (82% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The Foundations for Digital Twins as Catalyzers of Biomedical Technological Innovation (FDT-BioTech) program supports inherently interdisciplinary research projects that underpin the mathematical and engineering foundations behind the development and use of digital twins and synthetic data in biomedical and healthcare applications, with a particular focus on digital, in silico models used in the evaluation of medical devices and the relevance of the developed models in addressing current and emerging challenges affecting the development and assessment of biomedical technologies. The goal of the FDT-BioTech initiative is to catalyze biomedical technological innovation through new foundational development of methods and algorithms relevant to digital twins and synthetic humans.
Who has won Mathematical and Physical Sciences grants before
From fiscal 2021 to 2025, Mathematical and Physical Sciences (47.049) awarded $8.5 billion across 14,898 grant awards, an average of $568,976 per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Association of Universities for Research in Astronomy, Inc. | Arizona | 22 | $725 million |
| Associated Universities Inc | Virginia | 18 | $646 million |
| California Institute of Technology | California | 148 | $316 million |
| Cornell University | New York | 179 | $256 million |
| Florida State University | Florida | 92 | $228 million |
Who has won Trans-NIH Research Support grants before
From fiscal 2021 to 2025, Trans-NIH Research Support (93.310) awarded $5.9 billion across 4,433 grant awards, an average of $1.3 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Duke University | North Carolina | 66 | $219 million |
| The Leland Stanford Junior University | California | 104 | $176 million |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Pennsylvania | 82 | $154 million |
| The Johns Hopkins University | Maryland | 95 | $152 million |
| Yale Univ | Connecticut | 85 | $149 million |
Who has won Computer and Information Science and Engineering grants before
From fiscal 2021 to 2025, Computer and Information Science and Engineering (47.070) awarded $5.3 billion across 10,918 grant awards, an average of $481,712 per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| University of Texas at Austin | Texas | 168 | $379 million |
| University of California, San Diego | California | 201 | $222 million |
| University of Illinois | Illinois | 208 | $208 million |
| Carnegie-Mellon University | Pennsylvania | 296 | $153 million |
| Georgia Tech Research Corp | Georgia | 211 | $142 million |
Applying now
This notice no longer takes applications. Apply under the newer notice, NSF 27-500, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is NSF 24-561 still open?
No. It closed on May 4, 2026. A newer notice is open: NSF 27-500, closes January 29, 2027 (83 days left).
Who can apply for Foundations for Digital Twins as Catalyzers of Biomedical Technological Innovation?
U.S. National Science Foundation accepted applications from the applicants described in the notice. The notice adds further conditions, so read its eligibility section.
What is the deadline for Foundations for Digital Twins as Catalyzers of Biomedical Technological Innovation?
Closed May 4, 2026. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
About $5.0 million in total across about 10 awards.
Who has won Mathematical and Physical Sciences grants before?
The largest recipients over five fiscal years were Association of Universities for Research in Astronomy, Inc., Associated Universities Inc, California Institute of Technology. The program made 14,898 awards worth $8.5 billion in that time.