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Grants / National Science Foundation / U.S. National Science Foundation

NSF 20-505: Transitions to Excellence in Molecular and Cellular Biosciences Research

Closed Closed Opportunity NSF 20-505

This grant is closed. A newer notice from the same program is open now: Major Research Instrumentation Program: (MRI) (NSF 27-500). Status: Closes January 29, 2027 (83 days left). It is in our archive of U.S. National Science Foundation notices from 2025.

U.S. National Science Foundation offered grants to any type of organization. It expected to make about 8 awards worth $6.0 million in total. It is no longer open on Grants.gov.

From the official notice on Grants.gov, last changed June 7, 2025. Checked November 7, 2026.

Key dates

PostedJune 6, 2025
Archived by Grants.govJune 7, 2025

Who can apply

This opportunity was open to any type of organization.

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Is this a realistic fit?

What the grant funds

The Division of Molecular and Cellular Biosciences (MCB) has developed a new opportunity to enable researchers with a strong track record of prior accomplishment to pursue a new avenue of research or inquiry. This funding mechanism is designed to facilitate and promote a PI’s ability to effectively adopt empowering technologies that might not be readily accessible in the PI’s current research environment or collaboration network. Transformative research likely spans disciplines and minimizing the practical barriers to doing so will strengthen research programs poised to make significant contributions. The award is intended to allow mid-career or later-stage researchers (Associate or Full Professor, or equivalent) to expand or make a transition in their research programs via a sabbatical leave or similar mechanism of professional development and then develop that research program in their own lab. This award will also enable the PI to acquire new scientific or technical expertise, facilitate the investigator’s competitiveness, and potentially lead to transformational impacts in molecular and cellular bioscience. The award would fund up to six months of PI salary during the first sabbatical or professional development year, followed by support for continued research for two subsequent years upon the PI’s return to normal academic duties. Through this solicitation MCB and NSF hope to develop a novel mechanism that will encourage investigators to expand and/or transition to new research areas aligned with MCB priorities, to increase retention of investigators in science, and to ensure a diverse scientific workforce that remains engaged in active research. Highest funding priority is given to proposals that have outstanding intellectual merit and broader impacts, while proposals with weaknesses in either category (or those that are perceived as likely to have an incremental impact) will not be competitive. Proposals should also demonstrate a strong record of prior accomplishment, a compelling plan for professional development that will enable the PI to forge a new direction in their scholarship, and a strong rationale for why this support is needed for the PI to become competitive in the new research area. Support for the proposed transition from the PI’s department, described in a letter from the department chair or equivalent, will also be required. Proposals that do not describe a plan for a transition in research direction will be considered unresponsive.

Category: Science and Technology and other Research and Development.

Who has won Biological Sciences grants before

From fiscal 2021 to 2025, Biological Sciences (47.074) awarded $4.2 billion across 6,885 grant awards, an average of $609,810 per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Battelle Memorial InstituteOhio8$381 million
Arizona State UniversityArizona57$108 million
Cornell UniversityNew York85$85.6 million
University of FloridaFlorida100$70.6 million
Michigan State University FoundationMichigan105$67.9 million

Top states: California ($471 million), Ohio ($463 million), New York ($288 million), Massachusetts ($180 million), Texas ($176 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, NSF 27-500, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is NSF 20-505 still open?

No. It is no longer open on Grants.gov. A newer notice is open: NSF 27-500, closes January 29, 2027 (83 days left).

Who can apply for Transitions to Excellence in Molecular and Cellular Biosciences Research?

U.S. National Science Foundation accepted applications from any type of organization.

What is the deadline for Transitions to Excellence in Molecular and Cellular Biosciences Research?

Closed. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

About $6.0 million in total across about 8 awards.

Who has won Biological Sciences grants before?

The largest recipients over five fiscal years were Battelle Memorial Institute, Arizona State University, Cornell University. The program made 6,885 awards worth $4.2 billion in that time.

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