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NSF 18-590: Plant Biotic Interactions

Closed Closed Opportunity NSF 18-590

This grant is closed. A newer notice from the same program is open now: Major Research Instrumentation Program: (MRI) (NSF 27-500). Status: Closes January 29, 2027 (83 days left). It is in our archive of U.S. National Science Foundation notices from 2025.

U.S. National Science Foundation offered grants to the applicants described in the notice. It expected to make about 30 awards worth $18.5 million in total. It is no longer open on Grants.gov.

From the official notice on Grants.gov, last changed June 7, 2025. Checked November 7, 2026.

Other notices with this title

U.S. National Science Foundation has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
NSF 20-576May 14, 2020Closes October 5, 2076 (18230 days left)Open

Key dates

PostedJune 6, 2025
Archived by Grants.govJune 7, 2025

Who can apply

This opportunity was open to the applicants described in the notice.

*Who May Submit Proposals: Proposals may only be submitted by the following: -Non-profit, non-academic organizations: Independent museums, observatories, research laboratories, professional societies and similar organizations located in the U.S. that are directly associated with educational or research activities. -Institutions of Higher Education (IHEs): Two- and four-year IHEs (including community colleges) accredited in, and having a campus located in the US, acting on behalf of their faculty members. Special Instructions for International Branch Campuses of US IHEs: If the proposal includes funding to be provided to an international branch campus of a US institution of higher education (including through use of sub-awards and consultant arrangements), the proposer must explain the benefit(s) to the project of performance at the international branch campus, and justify why the project activities cannot be performed at the US campus. - USDA/NIFA Eligible applicants include: (1) State agricultural experiment stations; (2) colleges and universities (including community colleges offering associate degrees or higher); (3) university research foundations; (4) other research institutions and organizations; (5) Federal agencies, (6) national laboratories; (7) private organizations or corporations; (8) individuals who are U.S. citizens, nationals, or permanent residents; and (9) any group consisting of 2 or more entities identified in (1) through (8). Eligible institutions do not include foreign and international organizations.

Is this a realistic fit?

What the grant funds

The Plant Biotic Interactions (PBI) program supports research on the processes that mediate beneficial and antagonistic interactions between plants and their viral, bacterial, oomycete, fungal, plant, and invertebrate symbionts, pathogens and pests. This joint NSF/NIFA program supports projects focused on current and emerging model and non-model systems, and agriculturally relevant plants. The program’s scope extends from fundamental mechanisms to translational efforts, with the latter seeking to put into agricultural practice insights gained from basic research on the mechanisms that govern plant biotic interactions. Projects must be strongly justified in terms of fundamental biological processes and/or relevance to agriculture and may be purely fundamental or applied or include aspects of both perspectives. All types of symbiosis are appropriate, including commensalism, mutualism, parasitism, and host-pathogen interactions. Research may focus on the biology of the plant host, its pathogens, pests or symbionts, interactions among these, or on the function of plant-associated microbiomes. The program welcomes proposals on the dynamics of initiation, transmission, maintenance and outcome of these complex associations, includingstudies of metabolic interactions, immune recognition and signaling, host-symbiont regulation, reciprocal responses among interacting species and mechanisms associated with self/non-self recognition such as those in pollen-pistil interactions. Explanatory frameworks shouldinclude molecular, genomic, metabolic, cellular, network and organismal processes, with projects guided by hypothesis and/or discovery driven experimental approaches. Strictly ecological projects that do not address underlying mechanisms are not appropriate for this program. Quantitative modeling in concert with experimental work is encouraged. Overall, the program seeks to support research that will deepen our understanding of the fundamental processes that mediate interactions between plants and the organisms with which they intimately associate and advance the application of that knowledge to benefit agriculture.

Category: Science and Technology and other Research and Development.

Who has won Biological Sciences grants before

From fiscal 2021 to 2025, Biological Sciences (47.074) awarded $4.2 billion across 6,885 grant awards, an average of $609,810 per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Battelle Memorial InstituteOhio8$381 million
Arizona State UniversityArizona57$108 million
Cornell UniversityNew York85$85.6 million
University of FloridaFlorida100$70.6 million
Michigan State University FoundationMichigan105$67.9 million

Top states: California ($471 million), Ohio ($463 million), New York ($288 million), Massachusetts ($180 million), Texas ($176 million).

Who has won Agriculture and Food Research Initiative (AFRI) grants before

From fiscal 2021 to 2025, Agriculture and Food Research Initiative (AFRI) (10.310) awarded $2.1 billion across 3,639 grant awards, an average of $580,234 per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
University of California, DavisCalifornia100$85.6 million
Purdue UniversityIndiana92$76.8 million
Iowa State University of Science and TechnologyIowa87$76.4 million
Texas A&m Agrilife ResearchTexas92$76.1 million
The Ohio State UniversityOhio72$70.1 million

Top states: California ($172 million), Texas ($134 million), Ohio ($85.8 million), Indiana ($85.5 million), Iowa ($79.4 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, NSF 27-500, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is NSF 18-590 still open?

No. It is no longer open on Grants.gov. A newer notice is open: NSF 27-500, closes January 29, 2027 (83 days left).

Who can apply for Plant Biotic Interactions?

U.S. National Science Foundation accepted applications from the applicants described in the notice. The notice adds further conditions, so read its eligibility section.

What is the deadline for Plant Biotic Interactions?

Closed. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

About $18.5 million in total across about 30 awards.

Who has won Agriculture and Food Research Initiative (AFRI) grants before?

The largest recipients over five fiscal years were University of California, Davis, Purdue University, Iowa State University of Science and Technology. The program made 3,639 awards worth $2.1 billion in that time.

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