| 1 | Health & Human Svc Commn TX · Austin | State and local governments | 261 | $189 billion |
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| 2 | TX Education Agency · Austin | State and local governments | 103 | $37 billion |
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| 3 | Texas Department of Transportation · Austin | State and local governments | 8,533 | $29 billion |
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| 4 | Texas Department of Agriculture · Austin | State and local governments | 184 | $17 billion |
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| 5 | Texas Workforce Commission · Austin | State and local governments | 145 | $16 billion |
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| 6 | Texas Division of Emergency Management · Austin | State and local governments | 69 | $14 billion |
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| 7 | Texas General Land Office · Austin | State and local governments | 71 | $5.7 billion |
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| 8 | Department of State Health Services · Austin | State and local governments | 162 | $3.6 billion |
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| 9 | Southwest Key Programs Inc · Austin | Nonprofits | 38 | $3.6 billion |
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| 10 | Texas Comptroller of Public Accounts · Austin | State and local governments | 3 | $3.4 billion |
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| 11 | Texas Department of Housing & Community Affairs · Austin | State and local governments | 54 | $2.4 billion |
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| 12 | Texas Water Development Board · Austin | State and local governments | 85 | $2.4 billion |
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| 13 | Dept Family & Protective SER · Austin | State and local governments | 73 | $2.3 billion |
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| 14 | University of Texas at Austin · Austin | Colleges and universities | 2,051 | $2.2 billion |
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| 15 | Baylor College of Medicine · Houston | Colleges and universities | 1,319 | $1.7 billion |
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| 16 | Attorney General of Texas · Austin | State and local governments | 38 | $1.7 billion |
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| 17 | The University of Texas Southwestern Medical Center · Dallas | Colleges and universities | 1,211 | $1.6 billion |
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| 18 | Compass Connections · San Antonio | Nonprofits | 20 | $1.4 billion |
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| 19 | Texas Office of the Governor · Austin | State and local governments | 70 | $1.4 billion |
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| 20 | Comptroller of Public Accounts · Austin | State and local governments | 11 | $1.3 billion |
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| 21 | Catholic Charities Diocese of Fort Worth Endowment, Inc. · Fort Worth | Nonprofits | 15 | $1.2 billion |
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| 22 | BCFS Health and Human Services · San Antonio | Nonprofits | 24 | $1.2 billion |
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| 23 | The Univeristy of Texas M.D. Anderson Cancer Center · Houston | Colleges and universities | 830 | $1.1 billion |
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| 24 | Metropolitan Transit Authority of Harris County · Houston | State and local governments | 36 | $1.1 billion |
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| 25 | Dallas Area Rapid Transit Inc · Dallas | Tribal governments and organizations | 32 | $1.1 billion |
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| 26 | University of Texas Health Science Center at Houston · Houston | Colleges and universities | 758 | $918 million |
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| 27 | Dallas/Fort Worth International Airport · Dallas | State and local governments | 34 | $882 million |
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| 28 | The University of Texas Health Science Center at San Antonio · San Antonio | Colleges and universities | 532 | $756 million |
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| 29 | Harris County · Houston | State and local governments | 112 | $741 million |
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| 30 | Texas a & M University · College Station | Colleges and universities | 718 | $704 million |
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| 31 | City of San Antonio · San Antonio | State and local governments | 108 | $694 million |
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| 32 | San Antonio Metropolitan Transit · San Antonio | Other | 20 | $620 million |
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| 33 | University of Texas Medical Branch at Galveston · Galveston | Colleges and universities | 362 | $612 million |
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| 34 | University of Houston System · Houston | Colleges and universities | 651 | $612 million |
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| 35 | Capital Metropolitan Transportation Authority · Austin | State and local governments | 37 | $581 million |
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| 36 | William Marsh Rice University · Houston | Colleges and universities | 756 | $534 million |
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| 37 | Texas Parks and Wildlife Department · Austin | State and local governments | 502 | $527 million |
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| 38 | Texas A&m Agrilife Research · College Station | Colleges and universities | 526 | $522 million |
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| 39 | Heidelberg Materials Us Inc · Irving | Businesses | 3 | $509 million |
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| 40 | Texas Commission on Environmental Quality · Austin | State and local governments | 82 | $485 million |
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| 41 | City of Houston · Houston | State and local governments | 59 | $480 million |
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| 42 | City of Houston · Houston | State and local governments | 39 | $464 million |
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| 43 | Lutheran Social Services of the South, Inc · Austin | Nonprofits | 32 | $463 million |
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| 44 | The University of Texas Rio Grande Valley · Edinburg | Colleges and universities | 380 | $462 million |
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| 45 | Texas Office of the Governor · Austin | State and local governments | 6 | $453 million |
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| 46 | Texas A&m Engineering Experiment Station · College Station | Colleges and universities | 655 | $447 million |
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| 47 | City of El Paso · El Paso | State and local governments | 99 | $445 million |
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| 48 | City of Houston · Houston | State and local governments | 40 | $444 million |
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| 49 | The University of Texas at San Antonio · San Antonio | Colleges and universities | 454 | $423 million |
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| 50 | The University of Texas at El Paso · El Paso | Colleges and universities | 381 | $409 million |
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| 51 | Prairie View A&m University · Prairie View | Colleges and universities | 187 | $398 million |
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| 52 | University of Texas at Arlington · Arlington | Colleges and universities | 488 | $383 million |
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| 53 | University of Texas at Dallas · Richardson | Colleges and universities | 509 | $378 million |
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| 54 | Texas State University · San Marcos | Colleges and universities | 307 | $375 million |
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| 55 | Texas Military Department · Austin | State and local governments | 111 | $372 million |
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| 56 | Texas Tech University System · Lubbock | Colleges and universities | 468 | $365 million |
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| 57 | Texas Southern University · Houston | Colleges and universities | 89 | $350 million |
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| 58 | Fort Worth Transportation Authority · Fort Worth | State and local governments | 30 | $339 million |
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| 59 | Exxon Mobil Corporation · Spring | Businesses | 1 | $332 million |
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| 60 | Texas Railroad Comm · Austin | State and local governments | 49 | $328 million |
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| 61 | Texas a & M Research Foundation · College Station | Colleges and universities | 7 | $325 million |
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| 62 | Family Endeavors, Inc. · San Antonio | Nonprofits | 51 | $319 million |
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| 63 | University of North Texas · Denton | Colleges and universities | 290 | $296 million |
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| 64 | Killeen Independent School District · Killeen | State and local governments | 6 | $282 million |
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| 65 | City of Austin Aviation Department · Austin | State and local governments | 19 | $281 million |
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| 66 | Sunnova Energy Corporation · Houston | Businesses | 1 | $281 million |
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| 67 | Housing Authority of the City of San Antonio · San Antonio | Tribal governments and organizations | 308 | $277 million |
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| 68 | Sunny Glen Children's Home · San Benito | Nonprofits | 5 | $264 million |
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| 69 | The University of North Texas Health Science Center at Fort Worth · Fort Worth | Colleges and universities | 112 | $262 million |
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| 70 | City of Dallas · Dallas | State and local governments | 67 | $248 million |
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| 71 | Region 19 Education Service Center · El Paso | Nonprofits | 5 | $243 million |
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| 72 | Texas a & M University System Health Science Center · College Station | Colleges and universities | 282 | $229 million |
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| 73 | Dallas County Texas · Dallas | State and local governments | 50 | $228 million |
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| 74 | Dallas College · Dallas | State and local governments | 32 | $223 million |
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| 75 | Houston City College · Houston | State and local governments | 20 | $206 million |
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| 76 | Bakerripley · Houston | Nonprofits | 21 | $205 million |
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| 77 | North Central Texas Council of Governments · Arlington | State and local governments | 58 | $204 million |
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| 78 | Technip Energies USA, Inc. · Houston | Businesses | 1 | $200 million |
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| 79 | The Methodist Hospital Research Institute · Houston | Nonprofits | 164 | $196 million |
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| 80 | Housing Authority of City of Houston · Houston | Tribal governments and organizations | 122 | $193 million |
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| 81 | Texas Department of Public Safety · Austin | State and local governments | 27 | $193 million |
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| 82 | Head Start of Greater Dallas Inc · Dallas | Nonprofits | 5 | $193 million |
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| 83 | San Miguel Electric Coop · Jourdanton | Nonprofits | 1 | $190 million |
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| 84 | Lone Star College System District · Spring | Colleges and universities | 9 | $188 million |
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| 85 | City of Dallas · Dallas | State and local governments | 15 | $188 million |
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| 86 | Alamo Community College District · San Antonio | State and local governments | 14 | $187 million |
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| 87 | City of Lubbock · Lubbock | State and local governments | 58 | $177 million |
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| 88 | Hidalgo County Headstart Program · Mcallen | State and local governments | 3 | $172 million |
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| 89 | Tarrant County College District · Fort Worth | Colleges and universities | 20 | $158 million |
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| 90 | Avance-Houston, Inc. · Houston | Nonprofits | 9 | $157 million |
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| 91 | Tarrant County · Fort Worth | State and local governments | 98 | $156 million |
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| 92 | Clean Energy Fund of Texas, Inc. · Missouri City | Nonprofits | 1 | $156 million |
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| 93 | Texas A&m Forest Service · College Station | Colleges and universities | 63 | $156 million |
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| 94 | City of Fort Worth · Fort Worth | State and local governments | 56 | $155 million |
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| 95 | Southwest Research Institute · San Antonio | Nonprofits | 214 | $152 million |
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| 96 | The Onestar National Service Commission, Inc. · Austin | State and local governments | 18 | $151 million |
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| 97 | South Texas College · Mcallen | State and local governments | 18 | $150 million |
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| 98 | Texas Biomedical Research Institute · San Antonio | Nonprofits | 61 | $149 million |
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| 99 | Motivation Education & Training Inc · New Caney | Nonprofits | 48 | $148 million |
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| 100 | Texas A&m Agrilife Extension Service · College Station | Colleges and universities | 134 | $147 million |
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