| 1 | Ohio Department of Medicaid · Columbus | State and local governments | 21 | $125 billion |
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| 2 | Ohio Department of Education · Columbus | State and local governments | 147 | $18 billion |
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| 3 | Ohio Department of Job & Family Services · Columbus | State and local governments | 273 | $12 billion |
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| 4 | Ohio Department of Transportation · Columbus | State and local governments | 11,508 | $11 billion |
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| 5 | Ohio Department of Development · Columbus | State and local governments | 113 | $3.4 billion |
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| 6 | Ohio Department of Health · Columbus | State and local governments | 199 | $2.8 billion |
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| 7 | The Ohio State University · Columbus | Colleges and universities | 2,457 | $2.3 billion |
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| 8 | The State of Ohio Office of Budget and Management · Columbus | State and local governments | 146 | $1.7 billion |
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| 9 | Ohio Department Mental Health · Columbus | State and local governments | 44 | $1.2 billion |
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| 10 | Case Western Reserve University · Cleveland | Colleges and universities | 967 | $1.1 billion |
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| 11 | Ohio Department of Children and Youth · Columbus | State and local governments | 40 | $1.0 billion |
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| 12 | Childrens Hospital Medical Center · Cincinnati | Nonprofits | 647 | $948 million |
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| 13 | Ohio Department of Public Safety, Emergency Managment Agency · Columbus | State and local governments | 58 | $932 million |
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| 14 | Greater Cleveland Regional Transit Authority · Cleveland | State and local governments | 32 | $790 million |
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| 15 | Cincinnati Univ of · Cincinnati | Colleges and universities | 755 | $789 million |
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| 16 | Opportunities for Ohioans with Disabilities Agency · Columbus | State and local governments | 28 | $684 million |
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| 17 | Battelle Memorial Institute · Columbus | Businesses | 45 | $631 million |
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| 18 | Executive Office State of Ohio · Columbus | State and local governments | 5 | $625 million |
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| 19 | Cleveland Clinic Lerner College of Medicine of Case Western Reserve University · Cleveland | Colleges and universities | 447 | $599 million |
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| 20 | Cleveland-Cliffs Steel Corporation · West Chester | Businesses | 2 | $574 million |
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| 21 | National Youth Advocate Program, Inc. · Columbus | Nonprofits | 14 | $533 million |
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| 22 | Department of Natural Resources · Columbus | State and local governments | 172 | $451 million |
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| 23 | Cuyahoga Metropolitan Housing Authority · Cleveland | State and local governments | 159 | $418 million |
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| 24 | Ohio Department of Aging · Columbus | State and local governments | 83 | $396 million |
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| 25 | Central Ohio Transit Authority · Columbus | State and local governments | 21 | $383 million |
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| 26 | Research Institute at Nationwide Children's Hospital · Columbus | Nonprofits | 255 | $374 million |
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| 27 | Attorney General of Ohio · Columbus | State and local governments | 31 | $290 million |
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| 28 | Southwest Ohio Regional Transit Authority · Cincinnati | Nonprofits | 27 | $272 million |
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| 29 | National Guard Ohio · Columbus | State and local governments | 73 | $262 million |
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| 30 | Greater Dayton Regional Transit Authority · Dayton | Other | 12 | $219 million |
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| 31 | Cincinnati Metropolitan Housing Authority · Cincinnati | State and local governments | 185 | $209 million |
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| 32 | Kent State University · Kent | Colleges and universities | 188 | $197 million |
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| 33 | Ohio University · Athens | Colleges and universities | 173 | $194 million |
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| 34 | Akron Metropolitan Housing Authority · Akron | State and local governments | 207 | $189 million |
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| 35 | Miami Valley Child Development Centers, Inc. · Dayton | Nonprofits | 6 | $188 million |
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| 36 | The Ohio State University · Columbus | Colleges and universities | 7 | $182 million |
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| 37 | City of Cleveland · Cleveland | State and local governments | 26 | $180 million |
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| 38 | Central State University · Wilberforce | Colleges and universities | 87 | $178 million |
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| 39 | Natural Resources, Ohio Department of, Division of Wildlife · Columbus | State and local governments | 56 | $159 million |
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| 40 | Growth Opportunity Partners, Inc · Cleveland | Nonprofits | 1 | $156 million |
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| 41 | Ohio Air Quality Development Authority · Columbus | State and local governments | 1 | $156 million |
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| 42 | City of Cincinnati · Cincinnati | State and local governments | 62 | $154 million |
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| 43 | Columbus Regional Airport Authority · Columbus | State and local governments | 32 | $151 million |
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| 44 | Child Development Council of Franklin County, Inc. · Columbus | Nonprofits | 3 | $144 million |
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| 45 | Emerald Development & Economic Network Inc · Cleveland | State and local governments | 48 | $141 million |
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| 46 | First Student, Inc. · Cincinnati | Businesses | 6 | $141 million |
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| 47 | Cuyahoga County · Cleveland | State and local governments | 6 | $140 million |
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| 48 | Metro Regional Transit Authority · Akron | Other | 8 | $138 million |
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| 49 | Great Lakes Community Action Partnership · Fremont | Nonprofits | 40 | $136 million |
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| 50 | Cleveland Cuyahoga County Port Authority · Cleveland | State and local governments | 6 | $135 million |
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| 51 | City of Columbus · Columbus | State and local governments | 48 | $134 million |
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| 52 | City of Dayton · Dayton | State and local governments | 65 | $131 million |
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| 53 | Step Forward · Cleveland | Nonprofits | 3 | $131 million |
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| 54 | Strategies to End Homelessness Inc · Cincinnati | State and local governments | 13 | $130 million |
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| 55 | University of Toledo · Toledo | Colleges and universities | 150 | $127 million |
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| 56 | Cincinnati Hamilton County · Cincinnati | Nonprofits | 5 | $126 million |
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| 57 | Ohio Office of Criminal Justice Services · Columbus | State and local governments | 55 | $119 million |
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| 58 | Lucas Metropolitan Housing Authority · Toledo | State and local governments | 64 | $118 million |
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| 59 | Cleveland State University · Cleveland | Colleges and universities | 94 | $116 million |
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| 60 | University Hospitals Cleveland Medical Center · Cleveland | Nonprofits | 24 | $115 million |
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| 61 | The University of Akron · Akron | Colleges and universities | 116 | $113 million |
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| 62 | Miami University · Oxford | Colleges and universities | 149 | $111 million |
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| 63 | Community Shelter Board · Columbus | State and local governments | 12 | $109 million |
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| 64 | Executive Office State of Ohio · Columbus | State and local governments | 11 | $109 million |
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| 65 | Columbus State Community College · Columbus | Colleges and universities | 23 | $108 million |
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| 66 | Ohio Department of Agriculture · Reynoldsburg | State and local governments | 146 | $107 million |
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| 67 | Toledo Area Regional Transit Authority · Toledo | Other | 17 | $104 million |
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| 68 | Public Utilities Commission Ohio · Columbus | State and local governments | 25 | $103 million |
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| 69 | University of Dayton · Dayton | Colleges and universities | 77 | $101 million |
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| 70 | Stark Metropolitan Housing Aut · Canton | State and local governments | 106 | $100 million |
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| 71 | Wright State University · Dayton | Colleges and universities | 73 | $99.3 million |
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| 72 | Ohio Department of Public Safety, State Highway Patrol · Columbus | State and local governments | 41 | $95.2 million |
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| 73 | City of Toledo · Toledo | State and local governments | 36 | $94.2 million |
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| 74 | Bowling Green State University · Bowling Green | Colleges and universities | 80 | $93.7 million |
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| 75 | Cuyahoga Community College · Cleveland | State and local governments | 34 | $93.1 million |
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| 76 | Dayton Metropolitan Housing Authority · Dayton | State and local governments | 92 | $92.6 million |
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| 77 | The Centers for Families and Children · Cleveland | Nonprofits | 7 | $90.4 million |
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| 78 | State of Ohio · Sandusky | State and local governments | 5 | $89.4 million |
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| 79 | Akron Summit Community Action Inc · Akron | Nonprofits | 13 | $85.9 million |
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| 80 | Cleveland, City of · Cleveland | State and local governments | 17 | $83.9 million |
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| 81 | University of Toledo · Toledo | Colleges and universities | 86 | $82.9 million |
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| 82 | Sinclair Community College · Dayton | Nonprofits | 35 | $82.8 million |
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| 83 | Council on Rural Service Programs, Inc. · Piqua | Nonprofits | 3 | $81.6 million |
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| 84 | Stark Area Regional Transit Authority · Canton | Other | 15 | $76.4 million |
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| 85 | Toledo Public Schools · Toledo | State and local governments | 13 | $76.1 million |
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| 86 | The Ohio State University · Columbus | Colleges and universities | 15 | $72.2 million |
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| 87 | Northeast Ohio Neighborhood Health Services Inc · Cleveland | Other | 7 | $69.3 million |
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| 88 | Laketran · Painesville | Other | 19 | $68.2 million |
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| 89 | Real Alloy Recycling, LLC. · Beachwood | Businesses | 1 | $67.3 million |
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| 90 | Lorain Metropolitan Housing Authority · Lorain | Tribal governments and organizations | 41 | $66.9 million |
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| 91 | Ironton and Lawrence County Area Community Action Organization · Ironton | Nonprofits | 13 | $62.5 million |
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| 92 | Ohio Commission on Service and Volunteerism · Columbus | State and local governments | 16 | $62.2 million |
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| 93 | Butler County Educational Service Center · Hamilton | Nonprofits | 7 | $61.8 million |
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| 94 | The Cleveland Clinic Foundation · Cleveland | Nonprofits | 63 | $61.8 million |
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| 95 | Alta Care Group, Inc · Youngstown | Nonprofits | 3 | $61.2 million |
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| 96 | Rail Development Commission Ohio · Columbus | State and local governments | 10 | $61.0 million |
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| 97 | Cuyahoga County Board of Health · Cleveland | State and local governments | 13 | $59.6 million |
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| 98 | Lorain County Community College District · Elyria | State and local governments | 19 | $59.2 million |
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| 99 | Community Action Agency of Columbiana County, Inc. · Lisbon | Nonprofits | 36 | $59.2 million |
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| 100 | Youngstown State University · Youngstown | Colleges and universities | 23 | $57.9 million |
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