Well Told Grants

Federal grant recipients / Massachusetts

Federal grants to Syntis Bio Inc

Dorchester, Massachusetts · Small businesses · UEI NG1VDVGBHC87

Syntis Bio Inc in Dorchester, Massachusetts received $3.8 million in federal grants from fiscal 2021 to 2025, across 5 awards. Its largest program was Diabetes, Digestive, and Kidney Diseases Extramural Research, with $3.5 million. In fiscal 2025 it was awarded $3.2 million.

From USAspending.gov award records, updated November 7, 2026.

By year

Federal grants to Syntis Bio Inc by fiscal year
Fiscal yearAwardsAmount
FY 20210$0
FY 20220$0
FY 20230$0
FY 20242$671,947
FY 20255$3.2 million

An award funded in several years counts in each of them, so yearly awards add up to more than the five-year total.

Programs that fund Syntis Bio Inc

Every program, fiscal 2021 to 2025
ProgramAwardsAmount
Diabetes, Digestive, and Kidney Diseases Extramural Research 93.8474$3.5 million
Child Health and Human Development Extramural Research 93.8651$347,016

Awarding agencies

AgencyAwardsAmount
Department of Health and Human Services5$3.8 million

Largest awards

The 5 largest awards by money obligated in fiscal 2021 to 2025
AwardProgramFirst actionAmount
Polymer epithelial lining for the oral delivery of macromolecules - project summary macromolecule drugs, specifically peptides, are an attractive therapeutic class given they are more potent and target specific than small molecules yet demonstrate superior tissue permeation and manufacturability com
ASST_NON_R44DK138869_075 on USAspending
Diabetes, Digestive, and Kidney Diseases Extramural ResearchApril 24, 2024$1.6 million
Development of an oral pill to mimic the effects of gastric bypass surgery - project summary obesity is a complex disease that disrupts hormonal and metabolic pathways, increasing the risk of chronic co- morbidities like diabetes, cardiovascular disease, and cancer. Obesity itself afflicts more than
ASST_NON_R44DK141341_075 on USAspending
Diabetes, Digestive, and Kidney Diseases Extramural ResearchSeptember 12, 2024$1.2 million
Development of an oral methionine-gamma-lyase enzyme for the treatment of homocystinuria - abstract - development of an oral methionine-gamma-lyase enzyme for the treatment of homocystinuria syntis bio is developing SYN-202, a novel methionine gamma-lyase (MGL) enzyme therapy aimed at correcting the
ASST_NON_R44HD118842_075 on USAspending
Child Health and Human Development Extramural ResearchSeptember 16, 2025$347,016
Development of once-daily oral treatment for maple syrup urine disease - project abstract syntis bio is advancing SYNT-213, a potentially transformative therapeutic approach for maple syrup urine disease (MSUD). This once-daily oral therapy combines the innovative gastrointestinal synthetic epitheli
ASST_NON_R44DK143766_075 on USAspending
Diabetes, Digestive, and Kidney Diseases Extramural ResearchSeptember 8, 2025$343,635
Oral therapeutics platform for treating inborn errors of amino acid metabolism - project abstract syntis bio is pioneering a groundbreaking approach to treat homocystinuria (HCU), a metabolic disorder caused by a defect in the cystathionine-Β-synthase enzyme, by developing a once-daily oral therapy
ASST_NON_R44DK142244_075 on USAspending
Diabetes, Digestive, and Kidney Diseases Extramural ResearchJuly 23, 2025$324,984

Amounts are net obligations: money committed, minus any amounts taken back. They are not payments. See how our data works.

Questions people ask

How much federal grant money does Syntis Bio Inc get?

$3.8 million in 5 grant awards from fiscal 2021 to 2025, as obligations reported to USAspending.gov.

Which agency gives Syntis Bio Inc the most?

The Department of Health and Human Services, with $3.8 million in 5 awards.

What is Syntis Bio Inc's largest federal grant?

$1.6 million under Diabetes, Digestive, and Kidney Diseases Extramural Research, with its first action in the period on April 24, 2024. That counts only the money obligated in fiscal 2021 to 2025.

Which federal programs fund Syntis Bio Inc?

Its largest are Diabetes, Digestive, and Kidney Diseases Extramural Research and Child Health and Human Development Extramural Research.

Other grant recipients in Dorchester

Largest federal grant recipients in Massachusetts · Federal grants in Massachusetts