Well Told Grants

Federal grant recipients / California

Federal grants to Trethera Corp

Sherman Oaks, California · Small businesses · UEI QB66ZMAUF5P7

Trethera Corp in Sherman Oaks, California received $10.8 million in federal grants from fiscal 2021 to 2025, across 10 awards. Its largest program was Allergy and Infectious Diseases Research, with $4.3 million. In fiscal 2025 it was awarded $5.1 million.

From USAspending.gov award records, updated November 7, 2026.

By year

Federal grants to Trethera Corp by fiscal year
Fiscal yearAwardsAmount
FY 20210$0
FY 20221$368,195
FY 20234$2.4 million
FY 20245$3.0 million
FY 20256$5.1 million

An award funded in several years counts in each of them, so yearly awards add up to more than the five-year total.

Programs that fund Trethera Corp

Every program, fiscal 2021 to 2025
ProgramAwardsAmount
Allergy and Infectious Diseases Research 93.8554$4.3 million
Cancer Treatment Research 93.3953$3.6 million
Vision Research 93.8671$1.6 million
Diabetes, Digestive, and Kidney Diseases Extramural Research 93.8472$1.3 million

Awarding agencies

AgencyAwardsAmount
Department of Health and Human Services10$10.8 million

Largest awards

The 10 largest awards by money obligated in fiscal 2021 to 2025
AwardProgramFirst actionAmount
Development of a novel, targeted small molecule inhibitor of the nucleoside salvage pathway through ind enabling studies and translational mouse models for acute disseminated encephalomyelitis (ADEM) - project summary acute disseminated encephalomyelitis (ADEM) is an autoimmune disease that can pres
ASST_NON_R44AI186534_075 on USAspending
Allergy and Infectious Diseases ResearchJuly 2, 2024$2.0 million
Development of a novel, targeted small molecule inhibitor of the nucleotide salvage pathway to treat underserved tumor types - project summary trethera, a clinical stage biopharmaceutical company, has developed a small molecule drug, TRE-515, to target the nucleoside salvage pathway via a key rate-l
ASST_NON_R44CA281485_075 on USAspending
Cancer Treatment ResearchMay 30, 2023$2.0 million
Development of a novel, targeted small molecule inhibitor of the nucleoside salvage pathway to treat optic neuritis - project summary optic neuritis (ON) is an acute autoimmune disease caused by immune attack on the myelin that protects the optic nerve leading to vision loss. Steroid treatments acce
ASST_NON_R42EY034397_075 on USAspending
Vision ResearchSeptember 15, 2022$1.6 million
Development of a novel, targeted small molecule inhibitor of the nucleoside salvage pathway through combinatorial murine studies to enable further clinical advancement in prostate tumors - project summary trethera, a clinical stage biopharmaceutical company, has developed a first-in-class small mole
ASST_NON_R44CA302066_075 on USAspending
Cancer Treatment ResearchAugust 18, 2025$1.1 million
Development of a novel, targeted small molecule inhibitor of the nucleoside salvage pathway to treat systemic lupus erythematosus - project summary systemic lupus erythematosus (SLE) is a challenging disease in need of new treatment options. Sle is a chronic, debilitating, heterogenous autoimmune di
ASST_NON_R44AI188587_075 on USAspending
Allergy and Infectious Diseases ResearchAugust 7, 2025$994,978
Development of a novel, targeted small molecule inhibitor of the nucleoside salvage pathway to treat crohn's disease - project summary crohn’s disease (CD) is a chronic autoimmune disease in which cells of the immune system attack gut tissue leading to diarrhea, fatigue, weight loss, fistulas, and a
ASST_NON_R42DK138578_075 on USAspending
Diabetes, Digestive, and Kidney Diseases Extramural ResearchSeptember 2, 2025$905,290
Development of a novel, targeted small molecule inhibitor of the nucleoside salvage pathway to treat systemic lupus erythematosus - project summary lupus is a chronic, systemic autoimmune disease in which cells of the immune system attack organ systems throughout the body including the kidneys, brai
ASST_NON_R41AI179213_075 on USAspending
Allergy and Infectious Diseases ResearchJune 21, 2023$610,850
Development of a novel, targeted small molecule inhibitor of the nucleoside salvage pathway to treat acute disseminated encephalomyelitis (ADEM) - project summary acute disseminated encephalomyelitis (ADEM) is an acute autoimmune disease that can present with fever and ataxia as well as loss of cons
ASST_NON_R41AI179191_075 on USAspending
Allergy and Infectious Diseases ResearchJuly 31, 2023$601,603
Development of a novel, targeted small molecule inhibitor of the nucleoside salvage pathway through murine studies to enable further clinical advancement in non-small-cell lung cancer - project summary non-small cell lung cancer (NSCLC) is the most common type of lung cancer, the leading cause of ca
ASST_NON_R44CA306475_075 on USAspending
Cancer Treatment ResearchSeptember 5, 2025$406,500
Development of a novel, targeted small molecule inhibitor of the nucleoside salvage pathway to treat crohn's disease - project summary crohn’s disease (CD) is a chronic autoimmune disease in which cells of the immune system attack gut tissue leading to diarrhea, fatigue, pain, and weight loss. Cd af
ASST_NON_R41DK138578_075 on USAspending
Diabetes, Digestive, and Kidney Diseases Extramural ResearchSeptember 19, 2023$395,119

Amounts are net obligations: money committed, minus any amounts taken back. They are not payments. See how our data works.

Questions people ask

How much federal grant money does Trethera Corp get?

$10.8 million in 10 grant awards from fiscal 2021 to 2025, as obligations reported to USAspending.gov.

Which agency gives Trethera Corp the most?

The Department of Health and Human Services, with $10.8 million in 10 awards.

What is Trethera Corp's largest federal grant?

$2.0 million under Allergy and Infectious Diseases Research, with its first action in the period on July 2, 2024. That counts only the money obligated in fiscal 2021 to 2025.

Which federal programs fund Trethera Corp?

Its largest are Allergy and Infectious Diseases Research, Cancer Treatment Research and Vision Research.

Largest federal grant recipients in California · Federal grants in California