# Cancer Treatment Research (93.395)

Source: https://welltoldgrants.com/programs/93-395-cancer-treatment-research/  
Publisher: Well Told Grants. Data: USAspending.gov and Grants.gov, updated November 7, 2026.

Cancer Treatment Research is run by Department of Health and Human Services. From fiscal 2021 to 2025 it awarded $5.6 billion in 3,622 grants, about $1.5 million per award.

## Objectives

To develop the means to cure as many cancer patients as possible and to control the disease in those patients who are not cured. Cancer Treatment Research includes the development and evaluation of improved methods of cancer treatment through the support and performance of both fundamental and applied laboratory and clinical research. Research is supported in the discovery, development, and clinical testing of all modes of therapy including: surgery, radiotherapy, chemotherapy, and biological therapy including molecularly targeted therapies, both individually and in combination. In addition, research is carried out in areas of nutritional support, stem cell and bone marrow transplantation, image guided therapies and studies to reduce toxicity of cytotoxic therapies, and other methods of supportive care that may supplement and enhance primary treatment. Small Business Innovation Research (SBIR) program: To expand and improve the SBIR program; to increase private sector commercialization of innovations derived from Federal research and development; to increase small business participation in Federal research and development; and to foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in technological innovation. Small Business Technology Transfer (STTR) program: To stimulate and foster scientific and technological innovation through cooperative research and development carried out between small business concerns and research institutions; to foster technology transfer between small business concerns and research institutions; to increase private sector commercialization of innovations derived from Federal research and development; and to foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in technological innovation.

## Funding by fiscal year

| Year | Amount | Awards |
|---|---|---|
| 2021 | $984 million | 1,608 |
| 2022 | $1.1 billion | 1,815 |
| 2023 | $1.1 billion | 1,900 |
| 2024 | $1.1 billion | 1,931 |
| 2025 | $1.3 billion | 1,879 |

## Largest recipients

| Recipient | State | Amount |
|---|---|---|
| The Univeristy of Texas M.D. Anderson Cancer Center | Texas | $188 million |
| Dana-Farber Cancer Institute, Inc. | Massachusetts | $185 million |
| Icahn School of Medicine at Mount Sinai | New York | $179 million |
| Public Health Institute | California | $168 million |
| Fred Hutchinson Cancer Center | Washington | $156 million |
| Sloan-Kettering Institute for Cancer Research | New York | $133 million |
| Brigham & Womens Hospital Inc | Massachusetts | $118 million |
| The Johns Hopkins University | Maryland | $110 million |
| The General Hospital Corporation | Massachusetts | $107 million |
| The Regents of the University of California, San Francisco | California | $105 million |
| Mayo Clinic Jacksonville (a Nonprofit Corporation) | Minnesota | $103 million |
| The Trustees of the University of Pennsylvania | Pennsylvania | $97.9 million |
| The Ohio State University | Ohio | $95.9 million |
| The University of Chicago | Illinois | $88.8 million |
| Beckman Research Institute of the City of Hope | California | $79.7 million |
| Regents of the University of Michigan | Michigan | $78.0 million |
| Oregon Health & Science University | Oregon | $76.6 million |
| The Leland Stanford Junior University | California | $75.6 million |
| University of Southern California | California | $75.5 million |
| NRG Oncology Foundation Inc | Pennsylvania | $73.3 million |

## Open opportunities

- [Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)](https://welltoldgrants.com/grants/par-24-214-academic-research-enhancement-award-area-for-undergraduate/), closes January 7, 2027
- [Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Clinical Trial Optional)](https://welltoldgrants.com/grants/par-25-079-academic-industrial-partnerships-aip-to-translate-and/), closes January 7, 2027
- [National Cancer Institute's Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis (R01 Clinical Trial Required)](https://welltoldgrants.com/grants/par-25-081-national-cancer-institute-s-investigator-initiated-early/), closes January 7, 2027
- [Glioblastoma Therapeutics Network (GTN) (U19 Clinical Trial Required)](https://welltoldgrants.com/grants/rfa-ca-27-005-glioblastoma-therapeutics-network-gtn-u19-clinical-trial/), closes January 11, 2027
- [NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)](https://welltoldgrants.com/grants/pa-27-100-nih-cdc-and-fda-small-business-innovation-research/), closes April 5, 2027
- [NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)](https://welltoldgrants.com/grants/pa-27-102-nih-small-business-technology-transfer-grant-parent-sttr/), closes April 5, 2027
- [Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)](https://welltoldgrants.com/grants/pa-24-254-change-of-recipient-organization-type-7-parent-clinical/), closes July 12, 2027
- [Successor-in-Interest (Type 6 Parent Clinical Trial Optional)](https://welltoldgrants.com/grants/pa-24-253-successor-in-interest-type-6-parent-clinical-trial/), closes July 17, 2027
- [NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/pa-25-080-nih-support-for-conferences-and-scientific-meetings-parent/), closes September 7, 2027
- [Bioengineering Partnerships with Industry (U01 Clinical Trial Optional)](https://welltoldgrants.com/grants/par-24-325-bioengineering-partnerships-with-industry-u01-clinical/), closes September 7, 2027
- [Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)](https://welltoldgrants.com/grants/rfa-ca-27-019-early-stage-development-of-informatics-technologies-for/), closes October 19, 2027
- [Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required)](https://welltoldgrants.com/grants/par-27-078-research-enhancement-award-program-reap-for-health/), closes October 25, 2027
- [Toward Translation of Nanotechnology Cancer Interventions (TTNCI; R01 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-25-336-toward-translation-of-nanotechnology-cancer-interventions/), closes November 15, 2027
- [Molecular Imaging of Inflammation in Cancer (R01 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-24-311-molecular-imaging-of-inflammation-in-cancer-r01-clinical/), closes January 7, 2028
- [Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional)](https://welltoldgrants.com/grants/par-25-175-integration-of-imaging-and-fluid-based-tumor-monitoring/), closes January 7, 2028
- [Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)](https://welltoldgrants.com/grants/par-25-148-academic-research-enhancement-award-area-for-undergraduate/), closes January 7, 2028
- [Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-25-134-academic-research-enhancement-award-area-for-undergraduate/), closes January 7, 2028
- [Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-25-298-research-enhancement-award-program-reap-for-health/), closes January 7, 2028
- [Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Optional)](https://welltoldgrants.com/grants/par-25-321-exploratory-developmental-bioengineering-research-grants/), closes January 7, 2028
- [Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-25-346-exploratory-developmental-bioengineering-research-grants/), closes January 7, 2028
- [NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/pa-25-304-nih-exploratory-developmental-research-project-grant-parent/), closes January 7, 2028
- [NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)](https://welltoldgrants.com/grants/pa-25-306-nih-exploratory-developmental-research-project-grant-parent/), closes January 7, 2028
- [NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/pa-25-301-nih-research-project-grant-parent-r01-clinical-trial/), closes January 7, 2028
- [Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-25-338-academic-industrial-partnerships-for-translation-of/), closes January 7, 2028
- [Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Optional)](https://welltoldgrants.com/grants/par-25-337-academic-industrial-partnerships-for-translation-of/), closes January 7, 2028
- [INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/rfa-od-27-003-include-project-exploratory-developmental-research-awards/), closes June 15, 2028
- [INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/rfa-od-27-004-include-project-transformative-research-awards-for-down/), closes June 15, 2028
- [INCLUDE Project: Clinical Trials Phased Awards for Down syndrome Research (R61/R33 Clinical Trial Required)](https://welltoldgrants.com/grants/rfa-od-27-005-include-project-clinical-trials-phased-awards-for-down/), closes June 15, 2028
- [Method to Extend Research in Time (MERIT) Award Extension Request (Type 4 eSubmission Clinical Trial Optional)](https://welltoldgrants.com/grants/par-25-324-method-to-extend-research-in-time-merit-award/), closes September 7, 2028
- [Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)](https://welltoldgrants.com/grants/pa-26-001-administrative-supplements-to-existing-nih-grants-and/), closes November 30, 2028
- [HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)](https://welltoldgrants.com/grants/rfa-ns-27-007-heal-initiative-non-addictive-analgesic-therapeutics/), closes February 20, 2029
- [SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)](https://welltoldgrants.com/grants/par-27-098-sbir-sttr-commercialization-readiness-pilot-crp-program/), closes April 5, 2029
- [NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)](https://welltoldgrants.com/grants/pa-27-101-nih-small-business-innovation-research-sbir-phase-iib/), closes April 5, 2029
- [NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional)](https://welltoldgrants.com/grants/pa-26-002-nih-collaborative-international-research-project-parent-pf5/), closes May 7, 2029
- [Centers for AIDS Research (CFAR) and Developmental Centers for AIDS Research (D-CFAR) (P30 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-28-090-centers-for-aids-research-cfar-and-developmental-centers/), closes May 25, 2029
- [NIH Research Program Projects (Parent P01 Clinical Trial Optional)](https://welltoldgrants.com/grants/pa-27-061-nih-research-program-projects-parent-p01-clinical-trial/), closes May 25, 2029
- [Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional)](https://welltoldgrants.com/grants/par-27-072-bioengineering-research-grants-brg-r01-clinical-trial/), closes July 5, 2029
- [Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2027, 2028, and 2029 (P50 Clinical Trial Required)](https://welltoldgrants.com/grants/par-28-022-specialized-programs-of-research-excellence-spores-in-human/), closes September 25, 2029
- [Precision Approaches in Radiation Synthetic Combinations (PAIRS, RP1 Clinical Trial Optional)](https://welltoldgrants.com/grants/par-26-152-precision-approaches-in-radiation-synthetic-combinations/), closes not stated
- [NCI Research Specialist Award for Core and Laboratory-based Scientists (R50 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-27-088-nci-research-specialist-award-for-core-and-laboratory/), closes not stated
- [Canine Cancer Immunotherapy Network (K9CIN; U01 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/rfa-ca-26-010-canine-cancer-immunotherapy-network-k9cin-u01-clinical-trial/), closes not stated
- [Single Source: Coordinating Center (CC) for the Small Cell Lung Cancer (SCLC) Consortium (U24 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-27-009-single-source-coordinating-center-cc-for-the-small/), closes not stated
- [Radiation Oncology-Biology Integration Network (ROBIN) Centers (U54 Clinical Trial Required)](https://welltoldgrants.com/grants/rfa-ca-27-003-radiation-oncology-biology-integration-network-robin/), closes not stated
- [Advanced Development and Sustainment of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)](https://welltoldgrants.com/grants/rfa-ca-28-003-advanced-development-and-sustainment-of-informatics/), closes not stated
- [Investigator-Focused Award (Parent R35)](https://welltoldgrants.com/grants/par-28-037-investigator-focused-award-parent-r35/), closes not stated