# Cancer Detection and Diagnosis Research (93.394)

Source: https://welltoldgrants.com/programs/93-394-cancer-detection-and-diagnosis-research/  
Publisher: Well Told Grants. Data: USAspending.gov and Grants.gov, updated October 31, 2026.

Cancer Detection and Diagnosis Research is run by Department of Health and Human Services. From fiscal 2021 to 2025 it awarded $2.7 billion in 1,943 grants, about $1.4 million per award.

## Objectives

To improve screening and early detection strategies and to develop accurate diagnostic techniques and methods for predicting the course of disease in cancer patients. Screening and Early Detection research includes development of strategies to decrease cancer mortality by finding tumors early when they are more amenable to treatment. Diagnosis research focuses on methods to determine the presence of a specific type of cancer; to predict its course and response to therapy, both a particular therapy or a class of agents; and to monitor the effect of the therapy and the appearance of disease recurrence. These methods include diagnostic imaging and direct analyses of specimens from tumor or other tissues. Support is also provided for establishing and maintaining resources of human tissue to facilitate research. Small Business Innovation Research (SBIR) program: To expand and improve the SBIR program; to increase private sector commercialization of innovations derived from Federal research and development; to increase small business participation in Federal research and development; and to foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in technological innovation. Small Business Technology Transfer (STTR) program: To stimulate and foster scientific and technological innovation through cooperative research and development carried out between small business concerns and research institutions; to foster technology transfer between small business concerns and research institutions; to increase private sector commercialization of innovations derived from Federal research and development; and to foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in technological innovation.

## Funding by fiscal year

| Year | Amount | Awards |
|---|---|---|
| 2021 | $487 million | 962 |
| 2022 | $509 million | 980 |
| 2023 | $572 million | 1,047 |
| 2024 | $533 million | 1,000 |
| 2025 | $596 million | 914 |

## Largest recipients

| Recipient | State | Amount |
|---|---|---|
| The Regents of the University of California, San Francisco | California | $114 million |
| Fred Hutchinson Cancer Center | Washington | $96.7 million |
| The Leland Stanford Junior University | California | $89.1 million |
| Sloan-Kettering Institute for Cancer Research | New York | $88.7 million |
| The Johns Hopkins University | Maryland | $86.5 million |
| The Univeristy of Texas M.D. Anderson Cancer Center | Texas | $81.6 million |
| The General Hospital Corporation | Massachusetts | $80.0 million |
| The Washington University | Missouri | $73.7 million |
| The Trustees of the University of Pennsylvania | Pennsylvania | $63.6 million |
| Regents of the University of Michigan | Michigan | $57.5 million |
| University of California, Los Angeles | California | $56.5 million |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Pennsylvania | $48.7 million |
| Research Institute at Nationwide Children's Hospital | Ohio | $42.2 million |
| The University of Texas Southwestern Medical Center | Texas | $38.5 million |
| Mayo Clinic | Minnesota | $36.7 million |
| University of Washington | Washington | $34.2 million |
| Dana-Farber Cancer Institute, Inc. | Massachusetts | $33.4 million |
| Vanderbilt University Medical Center | Tennessee | $33.2 million |
| University of California, San Diego | California | $32.2 million |
| Duke University | North Carolina | $31.6 million |

## Open opportunities

- [Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/rfa-ca-27-002-advanced-development-and-validation-of-emerging/), closes November 10, 2026
- [Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/rfa-ca-27-001-early-stage-innovative-technology-development-for-basic-and/), closes November 10, 2026
- [Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)](https://welltoldgrants.com/grants/pa-23-317-competing-revisions-to-existing-nih-single-project-research/), closes November 24, 2026
- [Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)](https://welltoldgrants.com/grants/par-24-214-academic-research-enhancement-award-area-for-undergraduate/), closes January 7, 2027
- [Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Clinical Trial Optional)](https://welltoldgrants.com/grants/par-25-079-academic-industrial-partnerships-aip-to-translate-and/), closes January 7, 2027
- [National Cancer Institute's Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis (R01 Clinical Trial Required)](https://welltoldgrants.com/grants/par-25-081-national-cancer-institute-s-investigator-initiated-early/), closes January 7, 2027
- [Glioblastoma Therapeutics Network (GTN) (U19 Clinical Trial Required)](https://welltoldgrants.com/grants/rfa-ca-27-005-glioblastoma-therapeutics-network-gtn-u19-clinical-trial/), closes January 11, 2027
- [Limited Competition: Biospecimen Banks to support NCI National Clinical Trials Network Biospecimen Banks (NCTN Biobanks) and the NCI Early-Phase and Experimental Clinical Trials Biospecimen Bank (EET Biobank) (U24 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/rfa-ca-28-004-limited-competition-biospecimen-banks-to-support-nci/), closes February 11, 2027
- [NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)](https://welltoldgrants.com/grants/pa-27-100-nih-cdc-and-fda-small-business-innovation-research/), closes April 5, 2027
- [NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)](https://welltoldgrants.com/grants/pa-27-102-nih-small-business-technology-transfer-grant-parent-sttr/), closes April 5, 2027
- [Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)](https://welltoldgrants.com/grants/pa-24-254-change-of-recipient-organization-type-7-parent-clinical/), closes July 12, 2027
- [Successor-in-Interest (Type 6 Parent Clinical Trial Optional)](https://welltoldgrants.com/grants/pa-24-253-successor-in-interest-type-6-parent-clinical-trial/), closes July 17, 2027
- [NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/pa-25-080-nih-support-for-conferences-and-scientific-meetings-parent/), closes September 7, 2027
- [Bioengineering Partnerships with Industry (U01 Clinical Trial Optional)](https://welltoldgrants.com/grants/par-24-325-bioengineering-partnerships-with-industry-u01-clinical/), closes September 7, 2027
- [Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)](https://welltoldgrants.com/grants/rfa-ca-27-019-early-stage-development-of-informatics-technologies-for/), closes October 19, 2027
- [Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required)](https://welltoldgrants.com/grants/par-27-078-research-enhancement-award-program-reap-for-health/), closes October 25, 2027
- [Molecular Imaging of Inflammation in Cancer (R01 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-24-311-molecular-imaging-of-inflammation-in-cancer-r01-clinical/), closes January 7, 2028
- [Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional)](https://welltoldgrants.com/grants/par-25-175-integration-of-imaging-and-fluid-based-tumor-monitoring/), closes January 7, 2028
- [Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)](https://welltoldgrants.com/grants/par-25-148-academic-research-enhancement-award-area-for-undergraduate/), closes January 7, 2028
- [Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-25-134-academic-research-enhancement-award-area-for-undergraduate/), closes January 7, 2028
- [Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-25-298-research-enhancement-award-program-reap-for-health/), closes January 7, 2028
- [Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Optional)](https://welltoldgrants.com/grants/par-25-321-exploratory-developmental-bioengineering-research-grants/), closes January 7, 2028
- [Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-25-346-exploratory-developmental-bioengineering-research-grants/), closes January 7, 2028
- [NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/pa-25-304-nih-exploratory-developmental-research-project-grant-parent/), closes January 7, 2028
- [NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)](https://welltoldgrants.com/grants/pa-25-306-nih-exploratory-developmental-research-project-grant-parent/), closes January 7, 2028
- [NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/pa-25-301-nih-research-project-grant-parent-r01-clinical-trial/), closes January 7, 2028
- [Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-25-338-academic-industrial-partnerships-for-translation-of/), closes January 7, 2028
- [Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Optional)](https://welltoldgrants.com/grants/par-25-337-academic-industrial-partnerships-for-translation-of/), closes January 7, 2028
- [Method to Extend Research in Time (MERIT) Award Extension Request (Type 4 eSubmission Clinical Trial Optional)](https://welltoldgrants.com/grants/par-25-324-method-to-extend-research-in-time-merit-award/), closes September 7, 2028
- [Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)](https://welltoldgrants.com/grants/pa-26-001-administrative-supplements-to-existing-nih-grants-and/), closes November 30, 2028
- [SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)](https://welltoldgrants.com/grants/par-27-098-sbir-sttr-commercialization-readiness-pilot-crp-program/), closes April 5, 2029
- [NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)](https://welltoldgrants.com/grants/pa-27-101-nih-small-business-innovation-research-sbir-phase-iib/), closes April 5, 2029
- [NIH Research Educational Program - Mentoring Activities & Networks (Parent R25/UE5 - Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/pa-27-035-nih-research-educational-program-mentoring-activities/), closes May 5, 2029
- [NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional)](https://welltoldgrants.com/grants/pa-26-002-nih-collaborative-international-research-project-parent-pf5/), closes May 7, 2029
- [Centers for AIDS Research (CFAR) and Developmental Centers for AIDS Research (D-CFAR) (P30 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-28-090-centers-for-aids-research-cfar-and-developmental-centers/), closes May 25, 2029
- [NIH Research Program Projects (Parent P01 Clinical Trial Optional)](https://welltoldgrants.com/grants/pa-27-061-nih-research-program-projects-parent-p01-clinical-trial/), closes May 25, 2029
- [Implementation Science to Advance HIV Prevention, Treatment, and Care (R61/R33 Clinical Trial Optional)](https://welltoldgrants.com/grants/rfa-ai-27-018-implementation-science-to-advance-hiv-prevention-treatment/), closes June 20, 2029
- [Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional)](https://welltoldgrants.com/grants/par-27-072-bioengineering-research-grants-brg-r01-clinical-trial/), closes July 5, 2029
- [Systematic Testing of Radionuclides in Preclinical Experiments (STRIPE, RP1 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-26-129-systematic-testing-of-radionuclides-in-preclinical/), closes not stated
- [NCI Research Specialist (Clinician Scientist) Award (R50 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-27-089-nci-research-specialist-clinician-scientist-award-r50/), closes not stated
- [NCI Research Specialist Award for Core and Laboratory-based Scientists (R50 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-27-088-nci-research-specialist-award-for-core-and-laboratory/), closes not stated
- [Canine Cancer Immunotherapy Network (K9CIN; U01 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/rfa-ca-26-010-canine-cancer-immunotherapy-network-k9cin-u01-clinical-trial/), closes not stated
- [Single Source: Coordinating Center (CC) for the Small Cell Lung Cancer (SCLC) Consortium (U24 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-27-009-single-source-coordinating-center-cc-for-the-small/), closes not stated
- [Radiation Oncology-Biology Integration Network (ROBIN) Centers (U54 Clinical Trial Required)](https://welltoldgrants.com/grants/rfa-ca-27-003-radiation-oncology-biology-integration-network-robin/), closes not stated
- [Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH2/UH3 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/par-26-091-assay-validation-of-high-quality-markers-for-clinical/), closes not stated
- [Implementation and Evaluation of Databases to Examine AIDS](https://welltoldgrants.com/grants/rfa-ai-28-025-implementation-and-evaluation-of-databases-to-examine-aids/), closes not stated
- [Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/rfa-ca-28-002-advanced-development-and-validation-of-emerging/), closes not stated
- [Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)](https://welltoldgrants.com/grants/rfa-ca-28-001-early-stage-innovative-technology-development-for-basic-and/), closes not stated
- [Advanced Development and Sustainment of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)](https://welltoldgrants.com/grants/rfa-ca-28-003-advanced-development-and-sustainment-of-informatics/), closes not stated
- [Investigator-Focused Award (Parent R35)](https://welltoldgrants.com/grants/par-28-037-investigator-focused-award-parent-r35/), closes not stated