# DoD Tick-Borne Disease, Therapeutic/Diagnostic Research Award

Source: https://welltoldgrants.com/grants/w81xwh-22-tbdrp-tdra-dod-tick-borne-disease-therapeutic-diagnostic-research-award/  
Official notice: https://www.grants.gov/search-results-detail/339371

> Defense Health Agency Contracting Activity - DHACA offered grants to any type of organization. It expected to make about 4 awards worth $4.2 million in total. Applications closed on August 25, 2022.

| Field | Value |
|---|---|
| Opportunity number | W81XWH-22-TBDRP-TDRA |
| Agency | Defense Health Agency Contracting Activity - DHACA |
| Status | Forecast |
| Deadline | August 25, 2022 |
| Award ceiling | not stated |
| Award floor | not stated |
| Expected awards | 4 |
| Total funding | $4.2 million |
| Cost sharing | not required |
| Assistance Listings | 12.420 |

## Who can apply

- Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"

## What the grant funds

The FY22 TBDRP Therapeutic/Diagnostic Research Award is intended to support hypothesis-driven therapeutic and diagnostic development research. Projects submitted under a Treatment Focus Area should be therapeutic evaluation studies designed to promote new ideas aimed at drug or treatment discovery that are still in the early/preclinical stages of development. Projects submitted under a Diagnosis Focus Area should propose diagnostic approaches that will be readily integrated into clinical settings. All research projects should have a translational potential and aim to improve patient care and/or the quality of life for military Service Members, Veterans, and their beneficiaries, as well as the American public living with Lyme disease and/or other tick-borne diseases. The proposed studies are expected to be empirical in nature and product-driven. Applicants with limited tick-borne disease experience are strongly encouraged to collaborate with experienced tick-borne disease investigators. Applicants with substantial tick-borne disease experience are strongly encouraged to partner with experts in therapeutic and diagnostic assay development and transition, particularly those from the commercial sector. Examples of the types of research that may be supported by this award include, but are not limited to: • Evaluation, maturation, and/or down-selection of potential therapeutic candidates in vitro and/or in vivo • Design, development, and evaluation of proof-of-concept diagnostic assays or devices using in vitro or ex vivo samples • High throughput screening and confirmation of candidate therapeutics obtained from screening or by other means• Testing new therapeutic modalities (agents, delivery mechanisms) using established and accepted preclinical models • Preliminary studies on formulation, stability and safety prior to Good Manufacturing Practice production methods and evaluation in advanced preclinical studies • Investigational New Drug application-enabling studies leading to the development of pharmacologic agents, including compound characterization, absorption, distribution, metabolism, and excretion (ADME) studies, and dose/response and toxicology studies to demonstrate safety and efficacy in relevant model systems • Investigational Device Exemption application-enabling studies leading to the development of devices, including prototype development and device characterization, to demonstrate safety and efficacy using relevant model systems or samples •…

## Questions people ask

### Is W81XWH-22-TBDRP-TDRA still open?

No. It closed on August 25, 2022. A newer notice is open: HT942526BCRPCREA2, closes November 18, 2026 (11 days left).

### Who can apply for DoD Tick-Borne Disease, Therapeutic/Diagnostic Research Award?

Defense Health Agency Contracting Activity - DHACA accepted applications from any type of organization.

### What is the deadline for DoD Tick-Borne Disease, Therapeutic/Diagnostic Research Award?

Closed August 25, 2022. Applications are no longer accepted; the program's newer notices are on this page when there are any.

### How much funding is available?

About $4.2 million in total across about 4 awards.

### Who has won Military Medical Research and Development grants before?

The largest recipients over five fiscal years were The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., The Univeristy of Texas M.D. Anderson Cancer Center, The Johns Hopkins University. The program made 5,470 awards worth $6.9 billion in that time.