# DoD Amyotrophic Lateral Sclerosis, Clinical Development Award

Source: https://welltoldgrants.com/grants/w81xwh-21-alsrp-cda-dod-amyotrophic-lateral-sclerosis-clinical-development-award/  
Official notice: https://www.grants.gov/search-results-detail/331546

> Defense Health Agency Contracting Activity - DHACA offered grants to any type of organization. It expected to make about 9 awards worth $7.2 million in total. Applications closed on July 15, 2021.

| Field | Value |
|---|---|
| Opportunity number | W81XWH-21-ALSRP-CDA |
| Agency | Defense Health Agency Contracting Activity - DHACA |
| Status | Forecast |
| Deadline | July 15, 2021 |
| Award ceiling | not stated |
| Award floor | not stated |
| Expected awards | 9 |
| Total funding | $7.2 million |
| Cost sharing | not required |
| Assistance Listings | 12.420 |

## Who can apply

- Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"

## What the grant funds

The intent of the FY21 ALSRP Clinical Development Award is to support correlative studies leveraging human-based ALS resources to enrich clinical trials or to optimize components of current ALS clinical care. Leveraging can refer to the use of existing well-characterized and highly curated resources or collaboration with ongoing clinical research to amplify potential gains in knowledge. Analysis of results and/or biosamples collected under these projects should be made broadly available through deposition in existing publicly available curated repositories and data platforms. Clinical intervention studies do not meet the intent of this funding opportunity. Investigators interested in intervention clinical trials should consider applying under the FY21 ALSRP Therapeutic/Biomarker Trial Pilot Award (Funding Opportunity Number: W81XWH-21- ALSRP-TBPTA). For information about these award mechanisms, see https://cdmrp.army.mil/funding/alsrp. Use of existing well-characterized and highly curated clinical resources is encouraged. Examples of human-based ALS resources include ongoing or completed clinical trial datasets, biorepositories of clinical specimens, large transcriptome/proteome/metabolomic datasets, and databases of clinical data and/or metadata. The applicant must demonstrate availability of, and accessibility to, the necessary resources to accomplish the proposed aims. Resources should be available at the time of application submission, however, collection of new specimens and/or data from participants in an existing cohort is allowed. Applications are encouraged to include diversity in their sample populations. A list of suitable resources can be found on the ALSRP web page (https://cdmrp.army.mil/ alsrp/resources/ALSRPresources). Other resources may be used, provided they have an adequate description of repository parameters and mechanisms for broad access. Examples of studies appropriate for submission to the Clinical Development Award include, but are not limited to: • Using human subject-based resources to better define subtypes, predict therapeutic response, or assess prognosis. Biomarker development or data analysis may be relevant to a specific therapeutic or class of therapeutics, or to a specific type of ALS (such as a particular genetic mutation) and does not have to broadly apply to all patients. · Correlating clinical trial-related biosamples, imaging, or epidemiological data with clinical outcomes.

## Questions people ask

### Is W81XWH-21-ALSRP-CDA still open?

No. It closed on July 15, 2021. A newer notice is open: HT942526BCRPCREA2, closes November 18, 2026 (11 days left).

### Who can apply for DoD Amyotrophic Lateral Sclerosis, Clinical Development Award?

Defense Health Agency Contracting Activity - DHACA accepted applications from any type of organization.

### What is the deadline for DoD Amyotrophic Lateral Sclerosis, Clinical Development Award?

Closed July 15, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.

### How much funding is available?

About $7.2 million in total across about 9 awards.

### Who has won Military Medical Research and Development grants before?

The largest recipients over five fiscal years were The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., The Univeristy of Texas M.D. Anderson Cancer Center, The Johns Hopkins University. The program made 5,470 awards worth $6.9 billion in that time.