# Miniaturization and Automation of Tissue Chip Systems (MATChS) (U43/U44 Clinical Trial Not Allowed)

Source: https://welltoldgrants.com/grants/rfa-tr-23-017-miniaturization-and-automation-of-tissue-chip-systems-matchs/  
Official notice: https://www.grants.gov/search-results-detail/351096

> National Institutes of Health offered grants to small businesses. Applications closed on November 17, 2025.

| Field | Value |
|---|---|
| Opportunity number | RFA-TR-23-017 |
| Agency | National Institutes of Health |
| Status | Forecast |
| Deadline | November 17, 2025 |
| Award ceiling | not stated |
| Award floor | not stated |
| Expected awards | not stated |
| Total funding | not stated |
| Cost sharing | not required |
| Assistance Listings | 93.350 |

## Who can apply

- Small businesses

Other Eligible Applicants include the following:Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

## What the grant funds

This NOFO provides support using the SBIR cooperative agreement mechanisms for the development of MATChS. Applications considered responsive to this would include those proposing research and development of tools and turnkey technologies for higher throughput automated measures with on-line sensing, rapid acquisition and analysis of data to reduce manual handling. Funded projects will result in an increased availability of miniaturized automated tissue chip platforms for use in drug development and across multiple applications as a major research tool in biomedical research laboratories. As a cooperative agreement, small business concerns (SBCs) will be expected to develop milestones and benchmarks, and work with NIH staff towards progress in the aims of the project to develop an automated system and demonstrable pathways to commercialization.

## Questions people ask

### Is RFA-TR-23-017 still open?

No. It closed on November 17, 2025.

### Who can apply for Miniaturization and Automation of Tissue Chip Systems (MATChS) (U43/U44 Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from small businesses. The notice adds further conditions, so read its eligibility section.

### What is the deadline for Miniaturization and Automation of Tissue Chip Systems (MATChS) (U43/U44 Clinical Trial Not Allowed)?

Closed November 17, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

### Who has won National Center for Advancing Translational Sciences grants before?

The largest recipients over five fiscal years were University of Pittsburgh - of the Commonwealth System of Higher Education, Vanderbilt University Medical Center, Duke University. The program made 867 awards worth $3.1 billion in that time.