# Transformative Technologies for Experimental and Computational RNome Characterization and Functional Analysis

Source: https://welltoldgrants.com/grants/rfa-rm-28-006-transformative-technologies-for-experimental-and/  
Official notice: https://www.grants.gov/search-results-detail/363474

> National Institutes of Health plans to offer grants of up to $500,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It expects to make about 10 awards worth $8.0 million in total. It is a forecast: the notice is expected around October 1, 2026, with applications due around February 15, 2027.

| Field | Value |
|---|---|
| Opportunity number | RFA-RM-28-006 |
| Agency | National Institutes of Health |
| Status | Forecast |
| Deadline | expected February 15, 2027 |
| Award ceiling | $500,000 |
| Award floor | not stated |
| Expected awards | 10 |
| Total funding | $8.0 million |
| Cost sharing | not required |
| Assistance Listings | 93.310 |

## Who can apply

- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

## What the grant funds

The NIH Common Fund, in partnership with other NIH Institutes and Centers, plans to issue Notices of Funding Opportunity (NOFOs) for the RNomics program, which seeks to develop tools for studying the full set of RNA molecules (the RNome) in cells and tissues. The program will support technologies and resources that enable integrated analysis of RNA sequences, modifications, structures, locations, interactions, and functions to advance understanding of health and disease. RNomics includes four initiatives: technology enhancement centers, transformative technologies, molecular standards, and a coordinating center. Applications are not being solicited at this time. This notice is being provided to give potential applicants time to develop meaningful collaborations and strong projects. This NOFO will support the transformative technologies initiative. These phased projects will develop new experimental and computational RNA technologies that address major limitations of current methods. Projects will focus on early-stage, high-risk ideas not yet demonstrated at scale or in biologically relevant systems. Priority areas include tools to sequence RNA, detect modifications, study RNA function, and analyze RNA across molecules, cells, and tissues. Projects that successfully complete Phase 1 milestones will be evaluated for transition to Phase 2. Phase 2 projects are expected to deliver validated tools for community use.

## Questions people ask

### Who can apply for Transformative Technologies for Experimental and Computational RNome Characterization and Functional Analysis?

National Institutes of Health accepts applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

### What is the deadline for Transformative Technologies for Experimental and Computational RNome Characterization and Functional Analysis?

Expected deadline February 15, 2027. Confirm the date and time in the official notice on Grants.gov.

### How much funding is available?

Awards of up to $500,000 each. About $8.0 million in total across about 10 awards.