# Pilot Projects to Enhance the Human Virome Program (R03, Clinical Trials Not Allowed)

Source: https://welltoldgrants.com/grants/rfa-rm-25-006-pilot-projects-to-enhance-the-human-virome-program/  
Official notice: https://www.grants.gov/search-results-detail/359131

> National Institutes of Health offered grants of up to $100,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on November 24, 2025.

| Field | Value |
|---|---|
| Opportunity number | RFA-RM-25-006 |
| Agency | National Institutes of Health |
| Status | Forecast |
| Deadline | November 24, 2025 |
| Award ceiling | $100,000 |
| Award floor | not stated |
| Expected awards | not stated |
| Total funding | not stated |
| Cost sharing | not required |
| Assistance Listings | 93.310 |

## Who can apply

- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)

Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; U.S. Territory or Possession.

## What the grant funds

The Common FundHuman Virome Program(HVP) aims to extensively and comprehensively characterize the human virome and create tools, models, and methods that will enable an in-depth study of its variation and composition in relation to host factors and its influence on health and disease. The purpose of this NOFO is to support small pilot projects that extend the goals of the HVP, including further validating, improving, and complementing existing and newly developed tools from the HVP program by leveraging human specimens collected from the cohorts under the program; samples from animals to promote the refinement, utilization, and translation of these tools to better serve the goals of the HVP program; expanding existing cohorts and/or biospecimen sampling sites for virome characterization; developing tools and methods to study the human virome; and defining interactions between the human virome and host. These pilot projects will encourage collaboration across the HVP and expand the consortium. Pilot projects should not overlap with existing HVP efforts. The R03 is intended to support small research projects that can be carried out in a short period of time with limited resources.

## Questions people ask

### Is RFA-RM-25-006 still open?

No. It closed on November 24, 2025. A newer notice is open: RFA-RM-27-024, closes October 22, 2027 (349 days left).

### Who can apply for Pilot Projects to Enhance the Human Virome Program (R03, Clinical Trials Not Allowed)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

### What is the deadline for Pilot Projects to Enhance the Human Virome Program (R03, Clinical Trials Not Allowed)?

Closed November 24, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

### How much funding is available?

Awards of up to $100,000 each.

### Who has been funded under RFA-RM-25-006?

NIH RePORTER lists 6 projects funded under RFA-RM-25-006 in fiscal 2026, at 6 institutions. The most were at UT Southwestern Medical Center, University of Rochester, University of California, San Diego.

### Who has won Trans-NIH Research Support grants before?

The largest recipients over five fiscal years were Duke University, The Leland Stanford Junior University, University of Pittsburgh - of the Commonwealth System of Higher Education. The program made 4,433 awards worth $5.9 billion in that time.