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Grants / Department of Health and Human Services / Centers for Disease Control and Prevention - ERA

World Trade Center Youth Research Coordinating Center (U54)

Forecast Expected deadline February 23, 2027 Opportunity RFA-OH-27-054

Centers for Disease Control and Prevention - ERA plans to offer grants of up to $10.0 million to any type of organization. It expects to make one award worth $50.0 million in total. It is a forecast: the notice is expected around November 24, 2026, with applications due around February 23, 2027.

From the official notice on Grants.gov, last changed July 31, 2026. Checked October 31, 2026.

Key dates

Forecast postedJuly 31, 2026
Expected postingNovember 24, 2026
Expected deadlineFebruary 23, 2027
Expected award dateJune 26, 2027

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Who can apply

This opportunity is open to any type of organization.

Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Applicants may not include foreign components, as defined in the HHS Grants Policy Statement. Applicants may include collaborators or consultants from foreign institutions.

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Is this a realistic fit?

What the grant funds

The National Institute for Occupational Safety and Health (NIOSH), World Trade Center (WTC) Health Program, plans to establish a WTC Youth Research Coordinating Center ("Center") through a U54 cooperative agreement. In December 2022, Congress amended the Public Health Service Act (42 U.S.C. § 300mm–51(c)) to direct the WTC Health Program Administrator to establish a research cohort for emerging health impacts on youth. The cohort must be of sufficient size to support future research studies on the health and educational impacts of exposures resulting from the September 11, 2001, terrorist attacks (9/11). The overall purpose of the Center is to: Establish and maintain a WTC Youth Research Cohort of individuals who were: 21 years of age or younger at the time of 9/11 exposure, including those exposed in utero. Within a certain distance of the WTC site on and after 9/11. Develop and implement research on the long-term health and educational (including developmental and cognitive) impacts of individuals exposed at a young age to 9/11. The Center will integrate multidisciplinary expertise in epidemiology, environmental and occupational health, information technology and data management, community-engaged recruitment and research, and related disciplines. Community engagement and effective stakeholder communication will be central to all Center activities. The Center will support four functional core activities: Planning, Administration, and Evaluation. Information Technology (IT) and Data Management. Communication, Outreach, and Community Engagement. Research and Related Activities. The expected public health impact includes addressing gaps in knowledge about the health and educational impacts associated with 9/11 among individuals exposed in utero or at a young age. It also includes improving understanding of the long-term effects of 9/11 exposures across the lifespan.

Category: Health.

How to apply

  1. Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
  2. Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
  3. Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.

Questions go to James Yiin, PhD, Scientific Program Official, jcy5@cdc.gov, 513-841-4271.

Open the official notice

Questions people ask

Who can apply for World Trade Center Youth Research Coordinating Center (U54)?

Centers for Disease Control and Prevention - ERA accepts applications from any type of organization. The notice adds further conditions, so read its eligibility section.

What is the deadline for World Trade Center Youth Research Coordinating Center (U54)?

Expected deadline February 23, 2027. Confirm the date and time in the official notice on Grants.gov.

How much funding is available?

Awards of up to $10.0 million each. About $50.0 million in total for one award.

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