# NIOSH Centers of Excellence for Total Worker Health® (U19)

Source: https://welltoldgrants.com/grants/rfa-oh-27-049-niosh-centers-of-excellence-for-total-worker-health/  
Official notice: https://www.grants.gov/search-results-detail/363369

> Centers for Disease Control and Prevention - ERA plans to offer grants of up to $1.4 million (at least $500,000) to any type of organization. It expects to make about 10 awards worth $58.5 million in total. It is a forecast: the notice is expected around November 16, 2026, with applications due around February 26, 2027.

| Field | Value |
|---|---|
| Opportunity number | RFA-OH-27-049 |
| Agency | Centers for Disease Control and Prevention - ERA |
| Status | Forecast |
| Deadline | expected February 26, 2027 |
| Award ceiling | $1.4 million |
| Award floor | $500,000 |
| Expected awards | 10 |
| Total funding | $58.5 million |
| Cost sharing | not required |
| Assistance Listings | 93.262 |

## Who can apply

- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"

Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the HHS Grants Policy Statement, are not allowed.

## What the grant funds

PURPOSE NIOSH intends to support the Centers of Excellence in Total Worker Health® (TWH). These Centers will conduct rigorous research and translation activities to prevent harmful exposures, improve working conditions, and advance worker well-being. The Centers will develop practical, scalable solutions for employers and workers. All projects must use the NIOSH Worker Well-Being Questionnaire (WellBQ) and share data with the HERO Worker Well-Being Clearinghouse. Large Research Projects require economic evaluation. PRIORITY AREAS • High-risk occupations: First responders, vehicle mechanics, and technicians, with emphasis on occupational exposures, related health risks, and prevention strategies • Young workers, SMEs • Chronic disease • Mental health, stress • Substance use disorder • Artificial intelligence (AI), digital technologies This is a multi-component NOFO. COMPONENT STRUCTURE Percentages indicate maximum share of total budget. Overall Component (Required) Provides Center leadership and integration. Applicants should show strong coordination, scientific direction, and alignment across projects. Administration, Evaluation, and Emerging Issues Core (Required; up to 15%) Supports management and Center-wide evaluation. Applicants should describe oversight, data governance, and quality assurance. Optional activities include emerging issues and shared research resources. Outreach, Dissemination, and Impact Core (Required; up to 15%) Supports communication, worker/employer engagement, training, translation, implementation, and dissemination strategies. Research Projects (Required; about 60 to 70%) Includes all research activities. Applicants may propose a mix of projects. Research project distinctions are based on scope and complexity rather than cost. Projects should demonstrate scientific rigor and potential for sustained impact. Small Research Projects (Required; at least one project; up to 3 years) Exploratory, feasibility, early-stage intervention, surveillance, or measurement studies. Priority areas: high-risk occupations, young workers, SMEs. Should show innovation and potential to expand. Large Research Projects (Required; at least one project; up to 5 years) Multiyear etiologic, mechanistic, intervention, or translational studies. Priority areas: chronic disease, mental health, substance use disorder. Economic evaluation is required. Projects should include strong design and analytic plans.

## Questions people ask

### Who can apply for NIOSH Centers of Excellence for Total Worker Health® (U19)?

Centers for Disease Control and Prevention - ERA accepts applications from any type of organization. The notice adds further conditions, so read its eligibility section.

### What is the deadline for NIOSH Centers of Excellence for Total Worker Health® (U19)?

Expected deadline February 26, 2027. Confirm the date and time in the official notice on Grants.gov.

### How much funding is available?

Awards of up to $1.4 million each. About $58.5 million in total across about 10 awards.