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Grants / Department of Health and Human Services / National Institutes of Health

Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)

Open Closes September 26, 2028 (696 days left) Opportunity RFA-OD-25-011

National Institutes of Health is offering grants to nonprofits, colleges and universities, state and local governments, small businesses and businesses. It expects to make about 2 awards worth $1.3 million in total. Applications close on September 26, 2028.

From the official notice on Grants.gov, last changed April 16, 2026. Checked October 31, 2026.

Key dates

PostedDecember 5, 2025
DeadlineSeptember 26, 2028
Archived by Grants.govDecember 19, 2028

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Who can apply

This opportunity is open to nonprofits, colleges and universities, state and local governments, small businesses and businesses.

Refer to Section III. Eligibility Information for additional information on eligibility. Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

More grants for nonprofits, colleges and universities, state and local governments, small businesses, businesses.

Is this a realistic fit?

What the grant funds

This Notice of Funding Opportunity (NOFO) encourages grant applications for Animal and Biological Material Resource Centers. These Centers provide support for special colonies of laboratory animals and associated services, as well as other resources such as informatics tools, reagents, cultures (cells, tissues, and organs) and genetic stocks that serve the biomedical research community in a variety of research areas on a local, regional, and national basis. The goal of projects supported by this NOFO is to provide research resources that facilitate optimization and enhancement of scientific rigor, transparency, and experimental reproducibility of biomedical research. Proposed Animal and Biological Material Resource Centers must have broad application to multiple NIH Institutes or Centers (ICs) to align with the ORIP"s NIH-wide mission (https://orip.nih.gov/about-orip). This funding opportunity is designed to support both continuation of existing resources and to develop new ones when appropriate. Of special interest of the announcement is a requirement of the Center"s close coordination with efforts to develop new approach methodologies (NAMs) that complement traditional animal-based research. These include cell culture, organoids, computational models, and microphysiological systems. Applied Research Component should include studies to generate comparative data to increase applicability of NAMs and promote integration of the most predictive human disease models. Prior to preparing an application, all applicants are strongly encouraged to consult with Scientific/Research staff to be advised on appropriateness of the intended resource plans for this program, competitiveness of a potential application, and ORIP's program priorities.

Category: Health.

How to apply

  1. Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
  2. Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
  3. Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.

Questions go to National Institutes of Health, ORIPDCM@mail.nih.gov, 301-402-2541.

Open the official notice

Questions people ask

Who can apply for Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)?

National Institutes of Health accepts applications from nonprofits, colleges and universities, state and local governments, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)?

Closes September 26, 2028 (696 days left). Confirm the date and time in the official notice on Grants.gov.

How much funding is available?

About $1.3 million in total across about 2 awards.

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