# HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed)

Source: https://welltoldgrants.com/grants/rfa-ns-23-006-heal-initiative-development-of-therapies-and-technologies/  
Official notice: https://www.grants.gov/search-results-detail/343550

> National Institutes of Health offered grants to small businesses. Applications closed on April 4, 2025.

| Field | Value |
|---|---|
| Opportunity number | RFA-NS-23-006 |
| Agency | National Institutes of Health |
| Status | Forecast |
| Deadline | April 4, 2025 |
| Award ceiling | not stated |
| Award floor | not stated |
| Expected awards | not stated |
| Total funding | not stated |
| Cost sharing | not required |
| Assistance Listings | 93.213, 93.233, 93.242, 93.273, 93.350, 93.351, 93.837, 93.838, 93.839, 93.840, 93.846, 93.853, 93.859, 93.865, 93.866 |

## Who can apply

- Small businesses

Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

## What the grant funds

The purpose of this Funding Opportunity Announcement (FOA) aims to speed scientific solutions to stem the national opioid public health crisis by supporting the development of therapies and technologies directed at enhanced pain management through the Small Business Innovation Research (SBIR) program. This FOA is focused on applications directed at improving pain treatment, including the development of new non-addictive medications and devices and objective pain measurement. In addition, NIH is interested in new screening tools and models focused specifically on pain and development of pain therapies.

## Questions people ask

### Is RFA-NS-23-006 still open?

No. It closed on April 4, 2025.

### Who can apply for HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from small businesses. The notice adds further conditions, so read its eligibility section.

### What is the deadline for HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed)?

Closed April 4, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

### Who has been funded under RFA-NS-23-006?

NIH RePORTER lists 15 projects funded under RFA-NS-23-006 in fiscal 2023 to 2026, at 15 institutions. The most were at Function Therapeutics, Inc., Plumeria Therapeutics, Inc., Cryo Ergonomics Inc.

### Who has won Research and Training in Complementary and Integrative Health grants before?

The largest recipients over five fiscal years were Yale Univ, The General Hospital Corporation, Duke University. The program made 653 awards worth $575 million in that time.