Well Told Grants

Grants / Department of Health and Human Services / National Institutes of Health

Limited Competition: John Lewis NIMHD Research Endowment Program (S21 Clinical Trial Not Allowed)

Forecast Expected deadline May 25, 2027 Opportunity RFA-MD-28-001

National Institutes of Health plans to offer grants of up to $2.0 million to colleges and universities. It expects to make about 6 awards worth $12.0 million in total. It is a forecast: the notice is expected around March 25, 2027, with applications due around May 25, 2027.

From the official notice on Grants.gov, last changed September 8, 2026. Checked October 31, 2026.

Key dates

Forecast postedSeptember 8, 2026
Expected postingMarch 25, 2027
Expected deadlineMay 25, 2027
Expected award dateJune 30, 2028

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Who can apply

This opportunity is open to colleges and universities.

Pursuant to Public Health Service Act section 464z-3(h), 42 USC 285t(h), as amended by Public Law 117-104, applicants for this program must include eligible public/private institutions of higher education that have current or former HRSA Centers of Excellence awards under Section 736 of the Public Health Service (PHS) Act and current or former NIMHD Centers of Excellence awards under Section 464z-4 of the PHS Act. Eligible institutions must have an endowment that is equal to or less than 50 percent of the national median of endowment funds at institutions that conduct similar biomedical research and training of health professionals.

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Is this a realistic fit?

What the grant funds

As authorized under section 464z-3(h) of the Public Health Service Act, the purpose of the John Lewis NIMHD Research Endowment Program is to strengthen the research infrastructure and training capacity at eligible institutions of higher education to facilitate health disparities research. Specific strategic objectives include: 1) improving the institutional physical infrastructure and acquisition of research equipment, 2) developing research-enabling technical expertise, 3) expansion of academic science programs relevant to scientific research, and 4) merit-based recruitment of highly accomplished researchers for open faculty positions. The John Lewis NIMHD Research Endowment Program does not directly support research projects. This is a Forecast for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

Category: Health.

How to apply

  1. Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
  2. Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
  3. Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.

Questions go to NIMHD DCHPS Scientific Team, NIMHDDCHPSSciTeam@mail.nih.gov, Please contact via e-mail..

Open the official notice

Questions people ask

Who can apply for Limited Competition: John Lewis NIMHD Research Endowment Program (S21 Clinical Trial Not Allowed)?

National Institutes of Health accepts applications from colleges and universities. The notice adds further conditions, so read its eligibility section.

What is the deadline for Limited Competition: John Lewis NIMHD Research Endowment Program (S21 Clinical Trial Not Allowed)?

Expected deadline May 25, 2027. Confirm the date and time in the official notice on Grants.gov.

How much funding is available?

Awards of up to $2.0 million each. About $12.0 million in total across about 6 awards.

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