# Single Source: Cardiothoracic Surgical Trials Network (CTSN) Data Coordinating Center (U01 Clinical Trial Required)

Source: https://welltoldgrants.com/grants/rfa-hl-27-002-single-source-cardiothoracic-surgical-trials-network-ctsn/  
Official notice: https://www.grants.gov/search-results-detail/359182

> National Institutes of Health offered grants of up to $8.0 million to the applicants described in the notice. It expected to make one award worth $8.0 million in total. Applications closed on July 7, 2026.

| Field | Value |
|---|---|
| Opportunity number | RFA-HL-27-002 |
| Agency | National Institutes of Health |
| Status | Forecast |
| Deadline | July 7, 2026 |
| Award ceiling | $8.0 million |
| Award floor | not stated |
| Expected awards | 1 |
| Total funding | $8.0 million |
| Cost sharing | not required |
| Assistance Listings | 93.233, 93.837, 93.838, 93.839, 93.840 |

## Who can apply

- Others (see text field entitled "Additional Information on Eligibility" for clarification)

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Only the following applicant is eligible to apply for this single source funding: Icahn School of Medicine at Mount Sinai. Please refer to Section I. Notice of Funding Opportunity Information for more details. Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

## What the grant funds

This is a Notice of Funding Opportunity (NOFO) for a Single Source that will invite an application from the eligible organization to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application will be peer-reviewed, and if it is not a meritorious application, it will not be funded. This single source NOFO is intended to support a Data Coordinating Center (DCC) to conduct the activities of the Cardiothoracic Surgical Trials Network (CTSN). The DCC will consist of two collaborating components including a Data Management and Analytics Center (DMAC) and a Clinical Coordination Center (CCC). NHLBI strongly encourages multi-PD/PI applications with two PDs/PIs; one PD/PI for the DMAC and one PD/PI for the CCC. The primary responsibility of the DCC is to oversee the conduct of multiple randomized clinical trials in the CTSN.The DCC will support regulatory and administrative activities, data collection and management, and statistical analysis and reporting of trial results in a timely manner. The DCC will promote collaboration and communication among CTSN investigators and the broader research community and will coordinate outreach activities including engaging foundations, research entities, and small businesses in trials of mutual interest and public health importance. The DCC is responsible for integrating the efforts of clinical sites, core laboratories, and other collaborators, and conducting long-term follow-up centrally via telephone follow-up at the DCC. The NHLBI anticipates that the DCC will manage a Clinical and Implementation Research Skills Program centrally. The clinical and implementation research scholars program will support the expanded integration of clinical skills with dissemination and implementation science scholarship to enhance implementation research capacity. The scholars program would be designed to foster additional research questions within CTSN as well as generate a cohort of researchers who would transport their scholarship as they transition to leadership positions in academic and clinical programs.

## Questions people ask

### Is RFA-HL-27-002 still open?

No. It closed on July 7, 2026.

### Who can apply for Single Source: Cardiothoracic Surgical Trials Network (CTSN) Data Coordinating Center (U01 Clinical Trial Required)?

National Institutes of Health accepted applications from the applicants described in the notice. The notice adds further conditions, so read its eligibility section.

### What is the deadline for Single Source: Cardiothoracic Surgical Trials Network (CTSN) Data Coordinating Center (U01 Clinical Trial Required)?

Closed July 7, 2026. Applications are no longer accepted; the program's newer notices are on this page when there are any.

### How much funding is available?

Awards of up to $8.0 million each. About $8.0 million in total for one award.

### Who has won Cardiovascular Diseases Research grants before?

The largest recipients over five fiscal years were The Trustees of the University of Pennsylvania, Brigham & Womens Hospital Inc, Regents of the University of Michigan. The program made 11,798 awards worth $15 billion in that time.