# Viral INfections in the Young Lung- The VINYL Clinical Consortium (UG3/UH3 Clinical Trial Optional)

Source: https://welltoldgrants.com/grants/rfa-hl-26-006-viral-infections-in-the-young-lung-the-vinyl/  
Official notice: https://www.grants.gov/search-results-detail/359951

> National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on November 10, 2025.

| Field | Value |
|---|---|
| Opportunity number | RFA-HL-26-006 |
| Agency | National Institutes of Health |
| Status | Forecast |
| Deadline | November 10, 2025 |
| Award ceiling | not stated |
| Award floor | not stated |
| Expected awards | not stated |
| Total funding | not stated |
| Cost sharing | not required |
| Assistance Listings | 93.838 |

## Who can apply

- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)

Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

## What the grant funds

The objective of this program is to create a consortium of clinical sites that will perform deep phenotyping in 1500 babies, infants, and toddlers (0-2 years of age) with viral lower respiratory tract infections (LRTI) and hospitalized with acute bronchiolitis, pneumonia and/or pediatric acute respiratory distress syndrome (PARDS), and longitudinal follow up of participants for evidence of lung disease including asthma at age 4-5 years. Bronchiolitis, a condition unique to the young lung, is the leading cause of hospitalization for viral LRTI in 02-year-old children, including those born preterm. There are critical knowledge gaps in defining the condition, predicting its severity, and understanding the reasons for hospitalization, including the immature host respiratory immune response to viral infection, heterogeneity in response to different viruses, current interventions, significant practice variation in diagnosis and management and subsequent impact on lung health. To meet the need for deep phenotyping, identify appropriate subgroups, refine the diagnosis and management of these vulnerable patients during their hospitalization, and identify prognostic biomarkers for future airway and parenchymal disease, we propose the VINYL (Viral INfections in the Young Lung) clinical consortium, a pragmatic observational study, to perform deep phenotypic characterization of 1500 babies, infants and toddlers admitted to the pediatric floor and pediatric intensive care unit with viral LRTI. A longitudinal follow-up of participants after discharge using electronic health records and questionnaires and assessment of respiratory status at age 4-5 years will elucidate pulmonary outcomes from early viral LRTI, specifically asthma. Neurocognitive and general development, and sleep will also be assessed during follow up.

## Questions people ask

### Is RFA-HL-26-006 still open?

No. It closed on November 10, 2025.

### Who can apply for Viral INfections in the Young Lung- The VINYL Clinical Consortium (UG3/UH3 Clinical Trial Optional)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

### What is the deadline for Viral INfections in the Young Lung- The VINYL Clinical Consortium (UG3/UH3 Clinical Trial Optional)?

Closed November 10, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

### Who has been funded under RFA-HL-26-006?

NIH RePORTER lists 1 project funded under RFA-HL-26-006 in fiscal 2026, at 1 institution.

### Who has won Lung Diseases Research grants before?

The largest recipients over five fiscal years were The General Hospital Corporation, New England Research Institutes Inc, The Trustees of the University of Pennsylvania. The program made 5 awards worth $8.7 million in that time.