# Health and Extreme Weather Solutions-Focused Research Hubs (U54 - Clinical Trial Optional)

Source: https://welltoldgrants.com/grants/rfa-es-28-002-health-and-extreme-weather-solutions-focused-research-hubs/  
Official notice: https://www.grants.gov/search-results-detail/362978

> National Institutes of Health plans to offer grants of up to $2.0 million to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It expects to make about 6 awards worth $18.0 million in total. It is a forecast: the notice is expected around November 27, 2026, with applications due around January 29, 2027.

| Field | Value |
|---|---|
| Opportunity number | RFA-ES-28-002 |
| Agency | National Institutes of Health |
| Status | Forecast |
| Deadline | expected January 29, 2027 |
| Award ceiling | $2.0 million |
| Award floor | not stated |
| Expected awards | 6 |
| Total funding | $18.0 million |
| Cost sharing | not required |
| Assistance Listings | 93.113 |

## Who can apply

- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations

## What the grant funds

The National Institute of Environmental Health Sciences (NIEHS) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications that propose translational research hubs with multiple highly integrated components focused on research, capacity building, and community/public health translation for regionally relevant topics related to the health impacts of extreme weather and cumulative exposures, including but not limited to wildfire smoke, extreme heat, flooding, hurricanes, drought, and other climate-related hazards affecting populations at heightened risk across the lifespan. Responsive applications will be led by a multidisciplinary team of investigators with non-academic partners, such as state and local public health departments, community-based organizations, Tribal entities, health care systems, and emergency preparedness agencies. Consortia of multiple institutions are encouraged, particularly those that demonstrate meaningful community engagement and balanced, mutually beneficial partnership structures. Research can be situated at different nodes on the translational research continuum, spanning from fundamental to implementation research with a focus on being problem-based and solutions oriented, and should clearly inform pathways to support implementation, scalability, and measurable public health impact. Award recipients will be expected to collaborate with the HEW Research Coordination and Data Center(s) and other members of the HEW Community of Practice, including participation in data harmonization efforts, shared metrics development, and cross-site dissemination activities. This NOFO will utilize the U54 activity code, that supports specialized centers that function as regional resources for targeted research initiatives, including support for infrastructure development, pilot projects, and partnerships with affected communities throughout the research lifecycle. The U54 is a cooperative agreement that anticipates substantial federal programmatic staff involvement to assist investigators in the achievement of project objectives, including coordination across funded hubs, strategic alignment with NIH priorities, and facilitation of cross-institute collaboration. Grant authorities that allow NIEHS to forecast this opportunity are as follows: 42 USC 285l (NIEHS specific); 42 USC sections 241 (NIH grant authorities).

## Questions people ask

### Who can apply for Health and Extreme Weather Solutions-Focused Research Hubs (U54 - Clinical Trial Optional)?

National Institutes of Health accepts applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

### What is the deadline for Health and Extreme Weather Solutions-Focused Research Hubs (U54 - Clinical Trial Optional)?

Expected deadline January 29, 2027. Confirm the date and time in the official notice on Grants.gov.

### How much funding is available?

Awards of up to $2.0 million each. About $18.0 million in total across about 6 awards.