Well Told Grants

Grants / Department of Health and Human Services / National Institutes of Health

NIDDK Multi-Purpose Resource-Related, Multi-Component Research Services Centers Cooperative Agreement (U2C - Clinical Trial Optional)

Forecast Expected deadline January 28, 2027 Opportunity RFA-DK-28-114

National Institutes of Health plans to offer grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It expects to make about 7 awards worth $9.0 million in total. It is a forecast: the notice is expected around November 28, 2026, with applications due around January 28, 2027.

From the official notice on Grants.gov, last changed July 1, 2026. Checked October 31, 2026.

Key dates

Forecast postedJuly 1, 2026
Expected postingNovember 28, 2026
Expected deadlineJanuary 28, 2027
Expected award dateNovember 1, 2027

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Who can apply

This opportunity is open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

This Notice of Funding Opportunity (NOFO) announcement invites applications for NIDDK Multi-Purpose Resource-Related Research, Multi-Component Centers Cooperative Agreement (U2C - Clinical Trial Not Allowed). To help increase rigor, reproducibility and cost efficiencies, U2C centers offer highly specialized cores that provide a range of topic focused services including but not limited to hands-on technical services, consulting, research/data coordination, or other research support services provided by nationally recognized experts. In contrast to other types of Core Centers, the U2C services should be largely provided to clients located at another institution where the needed service or expertise is not available. Provided services enable high impact research within NIDDK’s research mission including but not limited to integrative physiology, metabolic phenotyping, nutrition, community engagement, communications, and/or data and research coordination. The disease focus should similarly be within NIDDK’s mission, such as obesity and diabetes. The clients for these services can be a consortia, research partners or individual investigators and should offer experiential training in at least one of the provided services. Applications to this NOFO can propose optional opportunities and/or a pilot and feasibility grant program depending on the needs of the program.

Category: Health.

How to apply

  1. Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
  2. Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
  3. Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.

Questions go to Division of Diabetes, Endocrinology and Metabolic Diseases, NIDDK_DEM@nih.gov, NIDDK_DEM@nih.gov.

Open the official notice

Questions people ask

Who can apply for NIDDK Multi-Purpose Resource-Related, Multi-Component Research Services Centers Cooperative Agreement (U2C - Clinical Trial Optional)?

National Institutes of Health accepts applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for NIDDK Multi-Purpose Resource-Related, Multi-Component Research Services Centers Cooperative Agreement (U2C - Clinical Trial Optional)?

Expected deadline January 28, 2027. Confirm the date and time in the official notice on Grants.gov.

How much funding is available?

About $9.0 million in total across about 7 awards.

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