# Tools for decentralized clinical trials for substance use disorder (R43/R44 Clinical Trials Optional)

Source: https://welltoldgrants.com/grants/rfa-da-25-052-tools-for-decentralized-clinical-trials-for-substance-use/  
Official notice: https://www.grants.gov/search-results-detail/350721

> National Institutes of Health offered grants of up to $295,924 to small businesses. Applications closed on March 14, 2024.

| Field | Value |
|---|---|
| Opportunity number | RFA-DA-25-052 |
| Agency | National Institutes of Health |
| Status | Forecast |
| Deadline | March 14, 2024 |
| Award ceiling | $295,924 |
| Award floor | not stated |
| Expected awards | not stated |
| Total funding | not stated |
| Cost sharing | not required |
| Assistance Listings | 93.279 |

## Who can apply

- Small businesses

Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

## What the grant funds

There are gaps that prevent the utilization of decentralized clinical trials (DCT) in substance use area. The existing sensors for physiological measurement are rarely used and may need further validation. There are no wearable or home-use detection devices on the market capable to measure substances of interest (e.g., methadone, buprenorphine, their metabolites, as well as the spectrum of illicit drugs). The devices in development are not intended for diagnostics or treatment. Most of the devices are intended for laboratory use. Most of the devices do not have standard software interface through which the devices can transmit the data to the study center.

## Questions people ask

### Is RFA-DA-25-052 still open?

No. It closed on March 14, 2024.

### Who can apply for Tools for decentralized clinical trials for substance use disorder (R43/R44 Clinical Trials Optional)?

National Institutes of Health accepted applications from small businesses. The notice adds further conditions, so read its eligibility section.

### What is the deadline for Tools for decentralized clinical trials for substance use disorder (R43/R44 Clinical Trials Optional)?

Closed March 14, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.

### How much funding is available?

Awards of up to $295,924 each.

### Who has been funded under RFA-DA-25-052?

NIH RePORTER lists 2 projects funded under RFA-DA-25-052 in fiscal 2025, at 2 institutions. The most were at Carina Medical, LLC, Addinex Technologies, Inc.

### Who has won Drug Use and Addiction Research Programs grants before?

The largest recipients over five fiscal years were Yale Univ, The Johns Hopkins University, University of California, San Diego. The program made 5,071 awards worth $7.3 billion in that time.